Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 10

A comparison of neutrophil-lymphocyte ratio and body fat percentage in hashimoto’s disease induced hypothyroid patients

Pages
2625–2630
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

NLR was identified statistically significantly low in the patient group when compared to the control group (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Inflammatory mechanisms are activated when the body mass index is increased and in cases of Hashimoto’s Thyroiditis (HT).
📊
Key Findings & Data:The objective of this study is to compare the NLR and body fat percentage in patients with Hashimoto’s disease induced hypothyroidism.Material and Methods: The study consisted of 29 patients diagnosed with HT induced hypothyroidism based on the clinical and laboratory findings.
💡
Conclusion & Impact:NLR was identified statistically significantly low in the patient group when compared to the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Inflammatory mechanisms are activated when the body mass index is increased and in cases of Hashimoto’s Thyroiditis (HT). The neutrophil-lymphocyte ratio (NLR), which is used as a new and easily accessible inflammatory marker, may be related to the body mass index. The objective of this study is to compare the NLR and body fat percentage in patients with Hashimoto’s disease induced hypothyroidism.Material and Methods: The study consisted of 29 patients diagnosed with HT induced hypothyroidism based on the clinical and laboratory findings. The control group consists of 29 healthy individuals who do not suffer from any disease known to increase TSH level. Body analysis is performed for all cases that are included in the study, and the height, weight, body fat percentage, lean body mass, visceral adiposity, basal metabolic rate, and body fluid percentages are calculated, and complete blood count, TSH, FT3, FT4, Anti-TPO tests were performed following 3-4 cc venous blood sample collection from all cases.Results: There were not any significant difference between the patient and control group in terms of gender, BMI, body fat percentage, lead body mass, visceral adiposity, fluid percentage, and basal metabolic rate data (p>0.05). NLR rate was 1.95±1.37 in patient group and 2.52±1.40 in control group. Significant difference was identified in NLR (p=0.025), fat percentage (p=0.002), lean mass (p=0.002) and visceral adiposity data (p=0.006) between the HT patients and control group when the male patients were removed from the groups. NLR was identified statistically significantly low in the patient group when compared to the control group (p

🔖

Cite This Article

EREN, M. A., KORKMAZ, E., ÇADIRCI, D., GÖNEL, A. (2022). A comparison of neutrophil-lymphocyte ratio and body fat percentage in hashimoto’s disease induced hypothyroid patients. Annals of Medical Research, Cilt: 27 - Sayı: 10, 2625–2630. https://ajindex.com/articles/446500

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Mazokopakis EE, Tzortzinis AA, Dalieraki-Ott EI, et al. Coexistence of Hashimoto’s thyroiditis with papillary thyroid carcinoma. A retrospective study. Hormones 2010;9:312-7
  2. Ahn D, Heo SJ, Park JH, et al. Clinical relationship between Hashimoto's thyroiditis and papillary thyroid cancer. Acta Oncologica 2011;50:1228-34
  3. Kyle L, Ball M, Doolan P. Effect of thyroid hormone on body composition in myxedema and obesity. New England J Med 1966;275:12-7
  4. Caturegli P, De Remigis A, Rose N. Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmunity Reviews 2014;13:391-7
  5. Arpaci D, Gurol G, Ergenc H, et al. A controversial new approach to address hematological parameters in Hashimoto’s thyroiditis. Clin Lab 2016;62:1225-31
  6. Feghali CA, Wright TM. Cytokines in acute and chronic inflammation. Front Biosci 1997;2:12-26 7. Van Snick J. Interleukin-6: an overview. Annual Rev Immunol 1990;8:253-78
  7. Hirano T. Interleukin-6 and its relation to inflammation and disease. Clin Immunol Immunopathol 1992;62:60- 5
  8. Furuncuoğlu Y, Tulgar S, Dogan A, et al. How obesity affects the neutrophil/ lymphocyte and platelet/ lymphocyte ratio, systemic immune-inflammatory index and platelet indices: a retrospective study. Eur Review Med Pharmacological Sci 2016;20:1300-6
  9. Templeton AJ, McNamara MG, Šeruga B, et al. Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. JNCI: J National Cancer Institute 2014;106:1-11
  10. Xue J, Huang W, Chen X, et al. Neutrophil-tolymphocyte ratio is a prognostic marker in acute ischemic stroke. J Stroke Cerebrovascular Diseases 2017;26:650-7
  11. Tamhane UU, Aneja S, Montgomery D, et al. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome. Am J Cardiol 2008;102:653-7
  12. Bhat T, Teli S, Rijal J, et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: a review. Expert Review Cardiovascular Therapy 2013;11:55-9
  13. Han C, Zeng J, Lin R, et al. The utility of neutrophil to lymphocyte ratio and fluid sequestration as an early predictor of severe acute pancreatitis. Scientific Reports 2017;7:1-8
  14. Friedman GD, Tekawa I, Grimm RH, et al. The leucocyte count: correlates and relationship to coronary risk factors: the CARDIA study. Int J Epidemiol 1990;19:889-93
  15. Barbesino G, Chiovato L. The genetics of Hashimoto's disease. Endocrinol Metabolism Clin North Am 2000;29:357-74
  16. Erdoğan G. Kolo