Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 6

High fructose consumption may have part in the pathophysiology of coronary artery ectasia

Pages
1536–1541
Publication Date
2022-10-12
DOI
—
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A comparativeanalysis was performed using the exact data of both groups including nutrient consumption.Results: The patient group with higher high-sensitivity C-reactive protein levels (p = 0.029), greater platelet count (p = 0.015), andincreased hypertension rate (p = 0.012) were observed to have higher energy in total (p = 0.008), carbohydrate (p = 0.003), andfructose intake (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: A coronary artery may partly become a half or one diameter larger than an adjoining normal one as observed on angiograms,which is called coronary artery ectasia (CAE).
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Key Findings & Data:Our study aims to determine the effects of the amount of fructoseconsumed on isolated CAE.Material and Methods: The study group consists of the patients with stable angina pectoris who had coronary angiography (CAG)reports dated from December 2018 to April 2019.
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Conclusion & Impact:A comparativeanalysis was performed using the exact data of both groups including nutrient consumption.Results: The patient group with higher high-sensitivity C-reactive protein levels (p = 0.029), greater platelet count (p = 0.015), andincreased hypertension rate (p = 0.012) were observed to have higher energy in total (p = 0.008), carbohydrate (p = 0.003), andfructose intake (p
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: A coronary artery may partly become a half or one diameter larger than an adjoining normal one as observed on angiograms,which is called coronary artery ectasia (CAE). There is strong evidence that oxidative stress and inflammation may contribute to theCAE pathophysiology, potentially due to higher fructose intake. Our study aims to determine the effects of the amount of fructoseconsumed on isolated CAE.Material and Methods: The study group consists of the patients with stable angina pectoris who had coronary angiography (CAG)reports dated from December 2018 to April 2019. Based on these reports, sampling was made as follow: the patient or CAE groupof 50 patients also with isolated CAE and the control group of 50 patients with normal coronary flow pattern (NCF). A comparativeanalysis was performed using the exact data of both groups including nutrient consumption.Results: The patient group with higher high-sensitivity C-reactive protein levels (p = 0.029), greater platelet count (p = 0.015), andincreased hypertension rate (p = 0.012) were observed to have higher energy in total (p = 0.008), carbohydrate (p = 0.003), andfructose intake (p

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Cite This Article

KUYUMCU, M. S., KUYUMCU, A. (2022). High fructose consumption may have part in the pathophysiology of coronary artery ectasia. Annals of Medical Research, Cilt: 27 - Sayı: 6, 1536–1541. https://ajindex.com/articles/446486

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References (14)

  1. Yilmaz H, Sayar N, Yilmaz M, et al. [Coronary artery ectasia: clinical and angiographical evaluation]. Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 2008;36:530-5
  2. Markis JE, Joffe CD, Cohn PF, et al. Clinical significance of coronary arterial ectasia. Am J Cardiol 1976;37: 217-22
  3. Kurum T, Dogutan H. [Nonatherosclerotic causes of coronary artery disease]. Anadolu kardiyoloji dergisi: AKD = Anatol J Cardiol 2003;3:348-52
  4. Sen N, Ozcan F, Uygur B, et al. [Elevated serum uric acid levels in patients with isolated coronary artery ectasia]. Turk Kardiyoloji Dernegi arsivi: Turk Kardiyoloji Derneginin yayin organidir 2009;37:467- 72
  5. Akturk E, Askin L, Nacar H, et al. Association of serum prolidase activity in patients with isolated coronary artery ectasia. Anatol J Cardiol 2018;19:110-6
  6. Gurlek A, Esenboga K, Ozcan OU, et al. Serum nitric oxide levels in patients with coronary artery ectasia. Anatol J Cardiol 2016;16:947-52
  7. Kundi H, Gok M, Cetin M, et al. Relationship between platelet-to-lymphocyte ratio and the presence and severity of coronary artery ectasia. Anatol J Cardiol 2016;16:857-62
  8. Erdogan T, Kocaman SA, Cetin M, et al. Increased YKL40 levels in patients with isolated coronary artery ectasia: an observational study. Anadolu kardiyoloji dergisi: AKD = Anatol J Cardiol 2013;13:465-70
  9. Tappy L, Le KA, Tran C, et al. Fructose and metabolic diseases: new findings, new questions. Nutrition (Burbank, Los Angeles County, Calif) 2010;26:1044-9
  10. Cirillo P, Pellegrino G, Conte S, et al. Fructose induces prothrombotic phenotype in human endothelial cells: A new role for "added sugar" in cardio-metabolic risk. J Thromb Thrombolysis 2015;40:444-51
  11. Conti FF, Brito Jde O, Bernardes N, et al. Cardiovascular autonomic dysfunction and oxidative stress induced by fructose overload in an experimental model of hypertension and menopause. BMC Cardiovasc Disord 2014;14:185
  12. Jaiswal N, Maurya CK, Arha D, et al. Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress. Apoptosis: An International J on Programmed Cell Death 2015;20:930-47
  13. Aksu T, Uygur B, Durukan Kosar M, et al. [Coronary artery ectasia: its frequency and relationship with atherosclerotic risk factors in patients undergoing cardiac catheterization]. Anadolu kardiyoloji dergisi: AKD = Anatol J Cardiol 2011;11:280-4
  14. Ozturk S, Yetkin E, Waltenberger J. Molecula