Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 8

Relationship between platelet-to-lymphocyte ratio and fractional flow reserve in left anterior descending artery with intermediate stenosis

Pages
2145–2150
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The two groups were evaluated for differencesusing a Student's unpaired t-test.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Platelet-to-lymphocyte ratio has been used as a determinant factor for coronary artery disease.
📊
Key Findings & Data:Since platelet activationis central to the initiation of atherosclerosis, our goal was to evaluate the relationship between platelet-to-lymphocyte ratio andfractional flow reserve (FFR) values in the left anterior descending artery (LAD) with intermediate coronary stenosis.Material and Methods: The present report encompassed 173 subjects having stable angina pectoris.
💡
Conclusion & Impact:The two groups were evaluated for differencesusing a Student's unpaired t-test.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Platelet-to-lymphocyte ratio has been used as a determinant factor for coronary artery disease. Since platelet activationis central to the initiation of atherosclerosis, our goal was to evaluate the relationship between platelet-to-lymphocyte ratio andfractional flow reserve (FFR) values in the left anterior descending artery (LAD) with intermediate coronary stenosis.Material and Methods: The present report encompassed 173 subjects having stable angina pectoris. These subjects were categorizedinto 2 groups: 91 subjects with a FFR less than or equal to 0.80 and 82 patients with a FFR greater than 0.80. The platelet-tolymphocyte ratio of each subject was determined from the complete blood count. The two groups were evaluated for differencesusing a Student's unpaired t-test. A p-value of

🔖

Cite This Article

ASOĞLU, R., AFŞİN, A., ATICI, A., ASOĞLU, E. (2022). Relationship between platelet-to-lymphocyte ratio and fractional flow reserve in left anterior descending artery with intermediate stenosis. Annals of Medical Research, Cilt: 27 - Sayı: 8, 2145–2150. https://ajindex.com/articles/446463

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Montalescot G, Sechtem U, Achenbach S, et al. 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 2013;34:2949–3003
  2. Hachamovitch R, Berman DS, Shaw LJ, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. Circulation 1998;97:535–43
  3. Tonino PA, De Bruyne B, Pijls NH, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 2009;360:213– 24
  4. Pijls NH, de Bruyne B, Peels K, et al. Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses. N Engl J Med 1996;334:1703–8
  5. Balta S, Celik T, Mikhailidis DP, et al. The relation between atherosclerosis and the neutrophil– lymphocyte ratio. Clin Appl Thromb 2016;22:405–11
  6. Snoep J, Roest M, Barendrecht A, et al. High platelet reactivity is associated with myocardial infarction in premenopausal women: a population- based case– control study. J Thromb Haemost 2010;8:906–13
  7. Ommen OSR, Gibbons GRJ, Hodge HDO, et al. Usefulness of the lymphocyte concentration as a prognostic marker in coronary artery disease. Am J Cardiol 1997;79:812
  8. Azab B, Shah N, Akerman M, et al. Value of platelet/ lymphocyte ratio as a predictor of all-cause mortality after non-ST-elevation myocardial infarction. J Thromb Thrombolysis 2012;34:326–34
  9. Smith RA, Ghaneh P, Sutton R, et al. Prognosis of resected ampullary adenocarcinoma by preoperative serum CA19-9 levels and platelet-lymphocyte ratio. J Gastrointest Surg 2008;12:1422–8
  10. Tobis J, Azarbal B, Slavin L. Assessment of intermediate severity coronary lesions in the catheterization laboratory. J Am Coll Cardiol 2007;49:839–48
  11. Pijls NH, Van Gelder B, Van der Voort P, et al. Fractional flow reserve: a useful index to evaluate the influence of an epicardial coronary stenosis on myocardial blood flow. Circulation 1995;92:3183–93
  12. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002;105:1135–43
  13. Celik T, Balta S, Mikhailidis DP, et al. The relation between no-reflow phenomenon and complete blood count parameters. Angiology 2017;68:381–8
  14. Falk E. Pathogenesis of atherosclerosis. J Am Coll Cardiol 2006;47:C7–12
  15. Balta S, Oz