SavedAdd your journal

Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 3

The effect of transcatheter aortic valve implantation on ventricular repolarization indices and neutrophil-to-lymphocyte ratio

Hakan KAYA
Pages
874–878
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was a statisticallysignificant decrease in QTd (26.0±9.1 vs. 21.3±7.2 ms; p=0.008), Tpe interval (88.43±12.6vs. 78.8±10.1 ms; p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The electrocardiographic QT dispersion (QTd), Tpe/QT ratio and Tpeak-Tend (Tpe) interval have been known as ventricularrepolarization indices.
📊
Key Findings & Data:Increased QTd,Tpe/QT ratio, inflammation and Tpe interval are associated with ventricular arrhythmia (VA).
💡
Conclusion & Impact:There was a statisticallysignificant decrease in QTd (26.0±9.1 vs. 21.3±7.2 ms; p=0.008), Tpe interval (88.43±12.6vs. 78.8±10.1 ms; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The electrocardiographic QT dispersion (QTd), Tpe/QT ratio and Tpeak-Tend (Tpe) interval have been known as ventricularrepolarization indices. Neutrophil–to- lymphocyte ratio (NLR) is an inflammatory marker that is newly described. Increased QTd,Tpe/QT ratio, inflammation and Tpe interval are associated with ventricular arrhythmia (VA). In patients with severe aortic stenosis(AS), VA has a key role in terms of morbidity and mortality. The present study aimed at examining whether transcatheter aortic valveimplantation (TAVI) affects ventricular repolarization indices and NLR.Material and Methods: Study population consisted of a total of 44 patients undergoing TAVI. Echocardiographic and laboratoryparameters of patients were evaluated before TAVI and sixth month after TAVI. Comparioson of electrocardiographic QTd, Tpe/QTratio, Tpe interval and NLR of the same petients were made before TAVI and sixth month after TAVI.Results: QT interval, corrected QT interval and heart rate were similar before and after TAVI (p>0.05 for all). There was a statisticallysignificant decrease in QTd (26.0±9.1 vs. 21.3±7.2 ms; p=0.008), Tpe interval (88.43±12.6vs. 78.8±10.1 ms; p

🔖

Cite This Article

KAYA, H. (2022). The effect of transcatheter aortic valve implantation on ventricular repolarization indices and neutrophil-to-lymphocyte ratio. Annals of Medical Research, Cilt: 27 - Sayı: 3, 874–878. https://ajindex.com/articles/446416

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Carabello BA, Paulus WJ. Aortic stenosis. Lancet 2009; 373:956-66
  2. Kvidal P, Bergström R, Malm T. Long-term follow-up of morbidity and mortality after aortic valve replacement with a mechanical valve prosthesis. Eur Heart J 2000; 21:1099-111
  3. Levy D, Anderson KM, Plehn J, et al. Echocardiographicallydetermined left ventricular structural and functional correlatesof complex or frequent ventricular arrhythmias on onehourambulatory electrocardiographic monitoring. Am J Cardiol 1987;59:836-40
  4. Castro Hevia J, Antzelevitch C, Tornés Bárzaga F,et al. Tpeak-Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricularfibrillation in patients with the Brugada syndrome. J Am Coll Cardiol 2006;47:1828-34
  5. Antzelevitch C, Sicouri S, Di Diego JM, et al. Does Tpeak-Tend provide an index of transmural dispersion of repolarization? Heart Rhythm 2007;4:1114-6
  6. Pereira IA, Borba EF. The role of inflammation, humoral and cell mediated autoimmunity in thepathogenesis of atherosclerosis. Swiss Med Wkly 2008;138:534-39
  7. L agrand WK, Visser CA, Hermens WT, et al. C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon? Circulation 1999;100:96-102
  8. Mountantonakis S, Deo R. Biomarkers in atrial fibrillation, ventricular arrhythmias and sudden cardiac death. Cardiovasc Ther 2012;30:74-80
  9. Avci A, Elnur A, Göksel A,et al. The relationship between neutrophil/lymphocyte ratio andcalcific aortic stenosis. Echocardiography 2014;31:1031-5
  10. Kucukseymen S, Cagirci G, Guven, R, et al. Is neutrophyl to lymphocyte ratio really auseful marker for all grades of degenerative aortic stenosis? Turk Kardiyol Dern Ars 2017;45:506-13
  11. Makkar RR, Fontane GP, Jilaihawi H,et al. Transcatheter aortic-valve replacement for inoperable severe aortic stenonsis. N engl J Med 2012; 366:1696-704
  12. Goldenberg I, Moss AJ, Zareba W. QT interval: how to measure it and what is “normal.” J Cardiovasc Electrophysiol 2006;17:333-6
  13. Vahanian A, Alfieri O, Andreotti F,et al. Guidelines on themanagement of valvular heart disease: The Task Force on theManagement of Valvular Heart Disease of the European Societyof Cardiology. Eur Heart J 2012; 33:2451-96
  14. Turina J, Hess O, Sepulcri F,et al. Spontaneous course ofaortic valve disease. Eur Heart J 1987;8:471-83
  15. Leon MB, Smith CR, Mack M,et al. PARTNER Trial Investigators.Transcatheter aortic-valve implantation for aorticstenosis in patients who cannot undergo surgery. N Engl J M