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Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 9

Serum TWEAK levels in patients with obstructive sleep apnea syndrome

Suleyman Emre KARAKURT
Haci Huseyin DERE
Nurcan KUM
Mehmet Ali ÇETİN
Turan TURHAN
Canan TOPCUOĞLU
Pages
2484–2488
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

When the correlation between TWEAK levels and sleep-related variables are examined, inversely correlation between TWEAK levels and apnea-hypopnea index, the percentage of total sleep time spent with oxygen saturation below 90% and oxygen desaturation index was found.Conclusion: Serum TWEAK levels in OSAS patients and its relation with sleep variables showed for the first time that TWEAK may be a new inflammatory biomarker for OSAS.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The purpose of the study is to research the serum TWEAK levels in obstructive sleep apnea syndrome (OSAS) patients.Material and Methods: Eighty-six subjects were admitted in the study, 59 being in the patient group and 27 in the control group.
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Key Findings & Data:The patient group was further divided into subgroups of severe OSAS and mild-moderate OSAS.
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Conclusion & Impact:When the correlation between TWEAK levels and sleep-related variables are examined, inversely correlation between TWEAK levels and apnea-hypopnea index, the percentage of total sleep time spent with oxygen saturation below 90% and oxygen desaturation index was found.Conclusion: Serum TWEAK levels in OSAS patients and its relation with sleep variables showed for the first time that TWEAK may be a new inflammatory biomarker for OSAS.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The purpose of the study is to research the serum TWEAK levels in obstructive sleep apnea syndrome (OSAS) patients.Material and Methods: Eighty-six subjects were admitted in the study, 59 being in the patient group and 27 in the control group. The patient group was further divided into subgroups of severe OSAS and mild-moderate OSAS. TWEAK levels between the groups were statistically compared. In addition, the correlation of sleep-related variables with TWEAK levels was investigated in the patientgroup.Results: TWEAK levels were lower in the patient group than in the control group. When the correlation between TWEAK levels and sleep-related variables are examined, inversely correlation between TWEAK levels and apnea-hypopnea index, the percentage of total sleep time spent with oxygen saturation below 90% and oxygen desaturation index was found.Conclusion: Serum TWEAK levels in OSAS patients and its relation with sleep variables showed for the first time that TWEAK may be a new inflammatory biomarker for OSAS.

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Cite This Article

KARAKURT, S. E., DERE, H. H., KUM, N., ÇETİN, M. A., TURHAN, T., TOPCUOĞLU, C. (2022). Serum TWEAK levels in patients with obstructive sleep apnea syndrome. Annals of Medical Research, Cilt: 27 - Sayı: 9, 2484–2488. https://ajindex.com/articles/446272

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