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Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 1

The comparison of effects of thiopental and ketofol on emergence agitation in patients with nasal surgery: A prospective, single-blind, randomized clinical trial

Emek GÜLDOĞAN
Erol KARAASLAN
Pages
52–57
Publication Date
2022-10-12
DOI
—
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The duration of stay in PACU was significantly lower in Group P (P:

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Objective & Hypothesis:Aim: Emergence agitation (EA) is a postanesthetic phenomenon that is common in patients who undergo nasal surgery with generalanesthesia, which manifests itself with confusion and violent behaviors and may cause serious problems such as bleeding in thesurgical site, unplanned removal of catheter or endotracheal tube.
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Key Findings & Data:In this study, we aimed to compare the effect of thiopental andketofol on EA formation after nasal surgery.Material and Methods: This study was performed as a prospective, randomized, single-blind, clinical trial in 80 patients undergoingnasal surgery.
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Conclusion & Impact:The duration of stay in PACU was significantly lower in Group P (P:
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Emergence agitation (EA) is a postanesthetic phenomenon that is common in patients who undergo nasal surgery with generalanesthesia, which manifests itself with confusion and violent behaviors and may cause serious problems such as bleeding in thesurgical site, unplanned removal of catheter or endotracheal tube. In this study, we aimed to compare the effect of thiopental andketofol on EA formation after nasal surgery.Material and Methods: This study was performed as a prospective, randomized, single-blind, clinical trial in 80 patients undergoingnasal surgery. The patients were randomly divided into two groups as thiopental (group P:40) and ketofol (group K:40). As theprimary outcome; Riker Sedation Agitation Scale (RSAS) was used in order to evaluate EA at the 5th minute after extubation. As thesecondary outcome; we aimed to evaluate predisposing factors causing EA.Results: The mean age of the patients was 38.55±13.12 in Group P, while it was 40.68±11.88 in Group K. The incidence of emergenceagitation (EA) was significantly higher in Group P than in Group K. There was a statistically significant difference between the twogroups (Group P:12 cases (30%), Group K:1 case (2.5%), P:0.001). Residual sedation values in PACU were similar in both groups(P:0.248). The duration of stay in PACU was significantly lower in Group P (P:

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Cite This Article

GÜLDOĞAN, E., KARAASLAN, E. (2022). The comparison of effects of thiopental and ketofol on emergence agitation in patients with nasal surgery: A prospective, single-blind, randomized clinical trial. Annals of Medical Research, Cilt: 27 - Sayı: 1, 52–57. https://ajindex.com/articles/446233

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