Some antioxidant parameters (superoxide dismutase, catalase, and reduced glutathione) and levels of malondialdehyde, which is a marker of oxidative stress, were measured in the blood samples of all participants.Results: There was a significant increase in oxidative stress marker MDA levels and a significant decrease in antioxidant enzyme (superoxide dismutase, catalase and reduced glutathione) levels in all individuals of the study group compared to the control group (p
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Aim: In this study, we wanted to investigate the oxidative stress level and some antioxidant parameters in angiography workers exposed to high dose x-ray.Material and Methods: The study included 47 angiography workers and 50 healthy control group.
📊
Key Findings & Data:Aim: In this study, we wanted to investigate the oxidative stress level and some antioxidant parameters in angiography workers exposed to high dose x-ray.Material and Methods: The study included 47 angiography workers and 50 healthy control group.
💡
Conclusion & Impact:Some antioxidant parameters (superoxide dismutase, catalase, and reduced glutathione) and levels of malondialdehyde, which is a marker of oxidative stress, were measured in the blood samples of all participants.Results: There was a significant increase in oxidative stress marker MDA levels and a significant decrease in antioxidant enzyme (superoxide dismutase, catalase and reduced glutathione) levels in all individuals of the study group compared to the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Aim: In this study, we wanted to investigate the oxidative stress level and some antioxidant parameters in angiography workers exposed to high dose x-ray.Material and Methods: The study included 47 angiography workers and 50 healthy control group. Some antioxidant parameters (superoxide dismutase, catalase, and reduced glutathione) and levels of malondialdehyde, which is a marker of oxidative stress, were measured in the blood samples of all participants.Results: There was a significant increase in oxidative stress marker MDA levels and a significant decrease in antioxidant enzyme (superoxide dismutase, catalase and reduced glutathione) levels in all individuals of the study group compared to the control group (p
🔖
Cite This Article
GUNDUZ, A. M., DEMİR, C. (2022). Evaluation of oxidative stress in angiography workers. Annals of Medical Research, Cilt: 27 - Sayı: 9, 2382–2385. https://ajindex.com/articles/446183
Dağdaş S. İyonlaştırıcı radyasyonlar ve kanser. Dicle Tıp Dergisi 2010;37:177-85
Neal R, Matthews RH, Lutz P, et al. Antioxidant role of N-acetyl cysteine isomers following high dose irradiation. Free Radic Biol Med 2003;34:689-95
Yan LJ. Positive oxidative stress in aging and agingrelated disease tolerance. Redox Biol 2014;2:165-9
Popov B, Gadjeva V, Valkanov P, et al. Lipid peroxidation, superoxide dismutase and catalase activities in brain tumor tissues. Arch Physiol Biochem 2003;111:455-9
Packer L. Methods in enzymology. Orlando: Academic Press; 1984
Beutler E, Kuhl W. Subunit structure of human hexosaminidase verified: interconvertibility of hexosaminidase isozymes. Nature 1975;258:262-4
Gutteridge JM. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995;41:1819-28
Freitinger Skalicka Z, Zolzer F, Beranek L, et al. Indicators of oxidative stress after ionizing and/ or non-ionizing radiation: superoxid dismutase and malondialdehyde. J Photochem Photobiol B 2012;117:111-4
Cooke MS, Evans MD, Dizdaroglu M, et al. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 2003;17:1195-214
Kovacic P, Somanathan R. Electromagnetic fields: mechanism, cell signaling, other bioprocesses, toxicity, radicals, antioxidants and beneficial effects. J Recept Signal Transduct Res 2010;30:214-26
Ceyhan AM, Akkaya VB, Gulecol SC, et al. Protective effects of β-glucan against oxidative injury induced by 2.45-GHz electromagnetic radiation in the skin tissue of rats. Arch Dermatol Res 2012;1-7
Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128
Akbari M, Ostadmohammadi V, Lankarani KB, et al. The Effects of Vitamin D Supplementation on Biomarkers of Inflammation and Oxidative Stress Among Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Horm Metab Res 2018;50:271-9
Al-Helaly LA, Ahmad TY. Oxidative Stress for X-Ray Diagnosis Workers in Mosul City. The Second Scientific Conference in Chemistry 2011;232-40
Celik H, Koyuncu I, Karakicik AZ, et al. Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments 2016;3:106-9