Journals / Annals of Medical Research / 2022 / Cilt: 29 - Sayı: 4

Etiological findings in cases with incidental liver metastasis and factors affecting survival

Pages
369–377
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

No significant correlation was found in the concordance analysis between CT and USG in detecting metastases In the survival analysis, higher alanine aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), gamma-glutamyl transpeptidase (GGT), cancer antigen 19- 9 (CA 19-9), total bilirubin (TBIL), direct bilirubin (DBIL) levels and lower albumin levels were found to be statistically significant in patients who died compared to aliving patients (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: In this study, the general characteristics of incidental liver metastasis and the factors affecting survival were investigated.
📊
Key Findings & Data:Materials and Methods: In our study, we retrospectively analyzed 216 patients with metastases in the liver at diagnosis.
💡
Conclusion & Impact:No significant correlation was found in the concordance analysis between CT and USG in detecting metastases In the survival analysis, higher alanine aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), gamma-glutamyl transpeptidase (GGT), cancer antigen 19- 9 (CA 19-9), total bilirubin (TBIL), direct bilirubin (DBIL) levels and lower albumin levels were found to be statistically significant in patients who died compared to aliving patients (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, the general characteristics of incidental liver metastasis and the factors affecting survival were investigated. Materials and Methods: In our study, we retrospectively analyzed 216 patients with metastases in the liver at diagnosis. Patients with previously known primary malignancy and liver failure due to chronic viral hepatitis were excluded from the study. Results: The etiological causes of metastatic liver lesions were cancer of unknown primary (CUP) 27.78%, pancreato biliary region tumors ( PBRT) 19.44%, colorectal cancer (CRC) 18.98% and 12.96% gastric cancer, in order of frequency. No significant correlation was found in the concordance analysis between CT and USG in detecting metastases In the survival analysis, higher alanine aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), gamma-glutamyl transpeptidase (GGT), cancer antigen 19- 9 (CA 19-9), total bilirubin (TBIL), direct bilirubin (DBIL) levels and lower albumin levels were found to be statistically significant in patients who died compared to aliving patients (p

🔖

Cite This Article

ŞAHİN, F. T., ÇAĞIN, Y. F. (2022). Etiological findings in cases with incidental liver metastasis and factors affecting survival. Annals of Medical Research, Cilt: 29 - Sayı: 4, 369–377. https://ajindex.com/articles/446131

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. References 1. Abbruzzese JL, Abbruzzese MC, Lenzi R, et al. Analysis of a diagnostic strategy for patients with suspected tumors of unknown origin. J Clin Oncol 1995, 13: 2094–2103. 2. Risio D, Percario R, Legnini M, et al. Diffuse large B-cell lymphoma of the colon with synchronous liver metastasis[202F?]: a rare case report mimicking metastatic colorectal adenocarcinoma. 2014, 14: 1–5. 3. Swaid F, Downs D, Rosemurgy AS. A practical approach to liver metastasis from unknown primary cancer[202F?]: What surgeons need to know. Cancer Genet 2016, 209: 559–566. 4. Parkin DM, Bray F, Ferlay J, et al. Global Cancer Statistics, 2002. CA Cancer J Clin 2005, 55: 74–108. 5. Adam R, Chiche L, Aloia T, et al. Hepatic Resection for Noncolorectal Nonendocrine Liver Metastases Analysis of 1452 Patients and Development of a Prognostic Model. Ann Surg.,244. Epub ahead of print 2006. 6. Petrakis D, Pentheroudakis G, Voulgaris E, et al. Prognostication in cancer of unknown primary (CUP): Development of a prognostic algorithm in 311 cases and review of the literature. Cancer Treatment Reviews 2013, 39: 701–708. 7. Hogan BA, Thornton FJ, Brannigan M, et al. Hepatic metastases from an unknown primary neoplasm (UPN): survival, prognostic indicators and value of extensive investigations. Clin Radiol 2002, 57: 1073–7. 8. Pavlidis N, Khaled H, Gaafar R. A mini review on cancer of unknown primary site: A clinical puzzle for the oncologists. Journal of Advanced Research. Epub ahead of print 2015. 9. Funaki B, Guest Editors MD, Ray CE, et al. Epidemiology of Primary and Secondar yLiver Cancers. 2006. 10. Conner JR, Hornick JL. Metastatic carcinoma of unknown primary: Diagnostic approach using immunohistochemistry. Advances in Anatomic Pathology, 22. Epub ahead of print 2015. 11. Dietrich CF, Kratzer W, Strobel D, et al. Assessment of metastatic liver disease in patients with primary extrahepatic tumors by contrast-enhanced sonography versus CT and MRI. World J Gastroenterol 2006, 12: 1699–1706. 12. Robinson PJ. The early detection of liver metastases. Cancer Imaging 2002, 2: 1–3. 13. Kadiyoran C, Cizmecioglu HA, Cure E, et al. Liver metastasis in colorectal cancer:Evaluation of segmental distribution. Prz Gastroenterol 2019, 14: 188–192. 14. Mazzaferro V, Pulvirenti A, Coppa J. Neuroendocrine tumors metastatic to the liver: How to select patients for liver transplantation? Journal of Hepatology 2007, 47: 460–466. 15. Stephens MR, Hopper AN, White SR, et al. Colonoscopy fi