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Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 11

Salivary cortisol and total antioxidant capacity levels of children with untreated dental caries

Hasan ULUSAL
Gül KESKİN
Hasan GÜNDOĞAR
Zübeyde UÇAR GÜNDOĞAR
Hakan ÖZDOĞRU
Pages
3008–3011
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are needed tobetter understand the background of the pathophysiological changes in these biochemical parameters and their relationship withcaries.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The study aimed to evaluate the relationship between the caries frequency, which was determined using different caries indexesand biological parameters such as salivary cortisol and total antioxidant capacity (TAC).Materials and Methods: 140 patients between the ages of 5-13 without systemic disease were included in the study.
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Key Findings & Data:Saliva sampleswere collected from patients whose DMFT (dmft) and PUFA (pufa) indexes were recorded, and these samples were centrifuged at5,000 rpm for 10 minutes.
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Conclusion & Impact:Further studies are needed tobetter understand the background of the pathophysiological changes in these biochemical parameters and their relationship withcaries.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The study aimed to evaluate the relationship between the caries frequency, which was determined using different caries indexesand biological parameters such as salivary cortisol and total antioxidant capacity (TAC).Materials and Methods: 140 patients between the ages of 5-13 without systemic disease were included in the study. Saliva sampleswere collected from patients whose DMFT (dmft) and PUFA (pufa) indexes were recorded, and these samples were centrifuged at5,000 rpm for 10 minutes. All samples were stored at -20 °C until measurement. Saliva cortisol and TAC levels were measured usingthe ELISA kit. All data were analyzed with SPSS v.22.Results: The mean DMFT/dmft and PUFA/pufa values were estimated as 6.72±4.37, 1.39±2.08, respectively. There was no significantcorrelation between caries indexes and biochemical parameters.However, there was a correlation between TAC and cortisol levelsin saliva.Conclusion: Within the limitations of this study, it was determined that high risk of caries in patients could not affect salivary cortisoland TAC levels; however, there was a positive correlation between salivary cortisol and TAC levels. Further studies are needed tobetter understand the background of the pathophysiological changes in these biochemical parameters and their relationship withcaries.

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Cite This Article

ULUSAL, H., KESKİN, G., GÜNDOĞAR, H., GÜNDOĞAR, Z. U., ÖZDOĞRU, H. (2022). Salivary cortisol and total antioxidant capacity levels of children with untreated dental caries. Annals of Medical Research, Cilt: 27 - Sayı: 11, 3008–3011. https://ajindex.com/articles/446100

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