Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 3

Neutrophil-lymphocyte ratio and severity ofatherosclerotic disease in stable coronary artery patientswith chronic total occlusion

Pages
506–510
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

When the syntax S is divided into 3 groups (Syntax score 1-22, 23-32,> 32) according to their score values, or 2 groups (Syntax score 1-21 and> 22 or 1-31 and> 31) according to their Syntax score values, NLR was higher in high Syntax score groups than in low groups (p 32) or 2 groups according to Syntax score values (Syntax score 1-21 and >22 or 1-31 and >31) as pointed in ESC revascularization guideline, high Syntax score group having a higher NLR than low group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with coronary artery disease.
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Key Findings & Data:The aim of this study is that NLR is associated with a greater CAD complexity in patients with stable angina pectoris with chronic total occlusion.Materials and Methods: A total of 495 patients who underwent coronary angiography and who had stable angina pectoris with chronic total occlusion in at least 1 vessel were included in the study.
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Conclusion & Impact:When the syntax S is divided into 3 groups (Syntax score 1-22, 23-32,> 32) according to their score values, or 2 groups (Syntax score 1-21 and> 22 or 1-31 and> 31) according to their Syntax score values, NLR was higher in high Syntax score groups than in low groups (p 32) or 2 groups according to Syntax score values (Syntax score 1-21 and >22 or 1-31 and >31) as pointed in ESC revascularization guideline, high Syntax score group having a higher NLR than low group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with coronary artery disease. The Syntax score is an angiographic tool used in grading the complexity of coronary artery disease (CAD). The aim of this study is that NLR is associated with a greater CAD complexity in patients with stable angina pectoris with chronic total occlusion.Materials and Methods: A total of 495 patients who underwent coronary angiography and who had stable angina pectoris with chronic total occlusion in at least 1 vessel were included in the study. The syntax score was used to determine coronary complexity.Results: Patients with CAD were evaluated by grouping according to 2 different criteria as pointed in the European Society of Cardiology (ESC) revascularization guide. When the syntax S is divided into 3 groups (Syntax score 1-22, 23-32,> 32) according to their score values, or 2 groups (Syntax score 1-21 and> 22 or 1-31 and> 31) according to their Syntax score values, NLR was higher in high Syntax score groups than in low groups (p 32) or 2 groups according to Syntax score values (Syntax score 1-21 and >22 or 1-31 and >31) as pointed in ESC revascularization guideline, high Syntax score group having a higher NLR than low group (p

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Cite This Article

Yılmaz, Y. (2022). Neutrophil-lymphocyte ratio and severity ofatherosclerotic disease in stable coronary artery patientswith chronic total occlusion. Annals of Medical Research, Cilt: 28 - Sayı: 3, 506–510. https://ajindex.com/articles/445995

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References (12)

  1. Ross R. Atherosclerosis-an inflammatory disease, N Engl J Med 1999;340:115-26
  2. Libby P. Vascular biology of atherosclerosis: overview and state of the art. Am J Cardiol 2003;91:3-6
  3. Soehnlein O. Multiple roles for neutrophils in atherosclerosis. Circ Res 2012:110:875-88
  4. Gibson PH, Cuthbertson BH, Croal BL, et al. Usefulness of neutrophil/lymphocyte ratio as predictor of newonset atrial fibrillation after coronary artery bypass grafting. Am J Cardiol 2010;105:186-91
  5. Fowler AJ, Agha RA. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiographyThe growing versatility of NLR. Atherosclerosis. 2013;228:44-5
  6. Poludasu S, Cavusoglu E, Khan W, et al. Neutrophil to lymphocyte ratio as a predictor of long term mortality in African Americans undergoing percutaneous coronary intervention. Clin Cardiol 2009;32:6-10
  7. Vatankulu MA, Sonmez O, Ertas G. A new parameter predicting chronic total occlusion of coronary arteries: platelet distribution width. Angiology 2014;65:60-4
  8. Yamane M. Current percutaneous recanalization of coronary chronic total occlusion. Rev Esp Cardiol 2012;65:265-77
  9. Christofferson RD, Lehmann KG, Martin GV, et al. Effect of chronic total coronary occlusion on treatment strategy. Am J Cardiol 2005;95:1088-91
  10. Srinivas VS, Brooks MM, Detre KM, et al. Contemporary percutaneous coronary intervention versus balloon angioplasty for multivessel coronary artery disease: a comparison of the National Heart, Lung and Blood Institute Dynamic Registry and the Bypass Angioplasty Revascularization Investigation (BARI) study. Circulation 2002;106:1627-33
  11. Sianos G, Morel MA, Kappetein AP, et al. SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. Euro Intervention. 2005;1:219-27
  12. Girasis C, Garg S, Räber L, et al. SYNTAX score and Clinical SYNTAX score as predictors of very longterm clinical outcomes in patients undergoing percutaneous coronary interventions: a substudy of SIRolimus-eluting stent compared with pacliTAXeleluting stent for coronary revascularization (SIRTAX) trial. Eur Heart J 2011;32:3115-27 13. Wijns W, Kolh P, Danchin N, et al. Guidelines on myocardial revascularization. Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS); European Association for Percutaneous Cardiovascular Interventions (EAPCI).