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Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 3

Association of adenovirus 36 and gynecomastiadevelopment: A case-control study

Serhat Sirekbasan
Harika Öykü Dinç
Bekir Kocazeybek
Oğuz Çörtük
Suat Sarıbaş
Özgür Pilancı
Melike Keskin
Eda Altan
Nuri Turan
Selçuk Köksal
Sevgi Ergin
Hüseyin Yılmaz
Mehmet Velidedeoğlu
Pages
537–541
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Serum leptin and adiponectin levels were detected to besignificantly different from each other (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The interaction of various adipokines secreted from adipose tissue during Adenovirus 36 (Ad-36) infection may causegynecomastia.
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Key Findings & Data:In this study, we aimed to evaluate the association between Ad-36 and gynecomastia development by determiningDNAs and antibodies of Ad-36, adiponectin, leptin, and IL-6 levels.
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Conclusion & Impact:Serum leptin and adiponectin levels were detected to besignificantly different from each other (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The interaction of various adipokines secreted from adipose tissue during Adenovirus 36 (Ad-36) infection may causegynecomastia. In this study, we aimed to evaluate the association between Ad-36 and gynecomastia development by determiningDNAs and antibodies of Ad-36, adiponectin, leptin, and IL-6 levels. Materials and Methods: Patient and control groups were composed of from 33 male adults with gynecomastia and 15 male adultswith anatomic disorders without gynecomastia, respectively. Serum neutralization assay (SNA) was used for the determination ofAd-36 antibodies and PCR method was used for the determination of Ad-36 DNA. Results: No Ad-36 DNA was found in the breast tissue samples. Ad-36 antibody levels were detected in the patient group withgynecomastia higher than the control group (p0.05). Serum leptin and adiponectin levels were detected to besignificantly different from each other (p

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Cite This Article

Sirekbasan, S., Dinç, H. Ö., Kocazeybek, B., Çörtük, O., Sarıbaş, S., Pilancı, Ö., Keskin, M., Altan, E., Turan, N., Köksal, S., Ergin, S., Yılmaz, H., Velidedeoğlu, M. (2022). Association of adenovirus 36 and gynecomastiadevelopment: A case-control study. Annals of Medical Research, Cilt: 28 - Sayı: 3, 537–541. https://ajindex.com/articles/445993

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