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Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 3

Effectiveness of ursodeoxycholic acid for the treatment ofgall bladder stones and sludge in pregnant women

Yusuf Tanrıkulu
Hüsnü Alptekin
Kazım Gemici
Ahmet Okus
Barış Sevinç
Pages
593–596
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It both relieves symptoms anddecreases the need for hospitalization.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The objective of this study is to evaluate the effectiveness of ursodeoxycholic acid (UDCA) for the treatment of symptomaticpregnant women with gall bladder stones and/or sludge.Materials and Methods: Gynecology and obstetrics clinic patients who were symptomatic with gallbladder stones and/ormicrolithiasis were included in the study.
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Key Findings & Data:Group 1 consisted of cases with conservative treatment and group 2 consisted of caseswith UDCA treatment.
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Conclusion & Impact:It both relieves symptoms anddecreases the need for hospitalization.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The objective of this study is to evaluate the effectiveness of ursodeoxycholic acid (UDCA) for the treatment of symptomaticpregnant women with gall bladder stones and/or sludge.Materials and Methods: Gynecology and obstetrics clinic patients who were symptomatic with gallbladder stones and/ormicrolithiasis were included in the study. Group 1 consisted of cases with conservative treatment and group 2 consisted of caseswith UDCA treatment. After treatment, the groups were compared for symptomatic and radiological relief and hospitalization.Results: For group 2, the mean treatment time with UDCA was 7.6 weeks. After treatment, a full cure was achieved in 28% of casesand symptomatic relief was achieved in 36% of cases. In group one; there was response to treatment in only 12% of cases. Inthe UDCA group, none of the patients needed hospitalization; however, in the conservative treatment group, five cases neededhospitalization.Conclusion: UDCA is effective for the treatment of symptomatic gall bladder disease in pregnancy. It both relieves symptoms anddecreases the need for hospitalization.

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Cite This Article

Tanrıkulu, Y., Alptekin, H., Gemici, K., Okus, A., Sevinç, B. (2022). Effectiveness of ursodeoxycholic acid for the treatment ofgall bladder stones and sludge in pregnant women. Annals of Medical Research, Cilt: 28 - Sayı: 3, 593–596. https://ajindex.com/articles/445930

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