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Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 9

Short stature and insulin-like growth Factor-I in neurofibromatosis Type I

Bilgin Yuksel
Faruk Incecik
Ozlem Herguner
Sakir Altunbasak
Habibe Koc Ucar
Refik Burgut
Pages
1763–1766
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Short stature, defined as height

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Certain NF1 patients have short stature due to unclear pathogenesis mechanisms.
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Key Findings & Data:The aim of this study is to investigate endocrinology parameters which could affect height in NF1.
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Conclusion & Impact:Short stature, defined as height
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Certain NF1 patients have short stature due to unclear pathogenesis mechanisms. The aim of this study is to investigate endocrinology parameters which could affect height in NF1. Materials and Methods: Clinical data of 48 NF1 patients aged 19 months to 18 years were collected by reviewing medical records. Current physical examination findings including height, weight, and pubertal status were recorded. Serum samples were obtained from all subjects for follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), free T4 (FT4), free T3 insulin-like growth factor (IGF1), and insulin-like growth binding protein3 (IGFBP3) levels. Results: Of the 48 patients, 34 (70%) had height below 50 percentiles. Short stature, defined as height

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Cite This Article

Yuksel, B., Incecik, F., Herguner, O., Altunbasak, S., Ucar, H. K., Burgut, R. (2022). Short stature and insulin-like growth Factor-I in neurofibromatosis Type I. Annals of Medical Research, Cilt: 28 - Sayı: 9, 1763–1766. https://ajindex.com/articles/445913

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