Journals / Annals of Medical Research / 2021 / Cilt: 28 - Sayı: 11

Cardiovascular disease in type 2 diabetes mellitus: Relationship between microalbuminuria and cardiovascular risk factors

Pages
2092–2102
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Body mass index, blood pressure (BP), LDL, glycated hemoglobin (HbA1c) and lipoprotein (a) levels were detected to be higher in patients with MAU (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: In this study, the relationship between cardiovascular disease (CVD) risk factors and microalbuminuria (MAU) in patients with type 2 diabetes mellitus (DM) was investigated.
📊
Key Findings & Data:Materials and Methods: The data of type 2 DM patients without CVD were evaluated retrospectively.
💡
Conclusion & Impact:Body mass index, blood pressure (BP), LDL, glycated hemoglobin (HbA1c) and lipoprotein (a) levels were detected to be higher in patients with MAU (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, the relationship between cardiovascular disease (CVD) risk factors and microalbuminuria (MAU) in patients with type 2 diabetes mellitus (DM) was investigated. Materials and Methods: The data of type 2 DM patients without CVD were evaluated retrospectively. Anthropometric measurements were made using calibrated standard devices. Biochemical data of the patients were obtained from the hospital information processing system. Patients with type 1 DM, history of CVD and diseases that may affect the MAU level were excluded from the study. Statistical analysis was done using SPSS 22.0. Results: The study included 300 type 2 DM patients with the mean age of 58.9±10.1. 56.7% of the cases (n=170) were female, and 43.3% (n=130) were male. 12.7% of the cases were obese (BMI>30 kg/m2 ). Body mass index, blood pressure (BP), LDL, glycated hemoglobin (HbA1c) and lipoprotein (a) levels were detected to be higher in patients with MAU (p

🔖

Cite This Article

Sozen, M., Koksalan, D., Solmaz, K., Altunoglu, E. (2022). Cardiovascular disease in type 2 diabetes mellitus: Relationship between microalbuminuria and cardiovascular risk factors. Annals of Medical Research, Cilt: 28 - Sayı: 11, 2092–2102. https://ajindex.com/articles/445792

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. DeFronzo RA. Pathogenesis of type 2 diabetes mellitus. Med Clin North Am 2004; 88:787-835
  2. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2014;37:81-90
  3. Pinchevsky Y, Butkow N, Raal FJ, et al. Demographic and clinical factors associated with development of type 2 diabetes: A review of the literature. Int J Gen Med 2020;13:121-9
  4. Singh GM, Danaei G, Farzadfar F, et al. The AgeSpecific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis. Wang G, editor. PLoS One. 2013;8:e65174
  5. Fox CS, Pencina MJ, Wilson PWF, et al. Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the framingham heart study. Diabetes Care 2008;31:1582- 4
  6. Tobe SW, McFarlane PA, Naimark DM. Microalbuminuria in diabetes mellitus. CMAJ 2002;167:499-503
  7. Kundu D, Roy A, Mandal T, et al. Relation of microalbuminuria to glycosylated hemoglobin and duration of type 2 diabetes. Niger J Clin Pract 2013;16:216
  8. Malik AR, Sultan S, Turner ST, Kullo IJ. Urinary albumin excretion is associated with impaired flow- and nitroglycerin-mediated brachial artery dilatation in hypertensive adults. J Hum Hypertens 2007;21:231-8
  9. Gross JL, De Azevedo MJ, Silveiro SP, et al. Diabetic nephropathy: Diagnosis, prevention, and treatment. Diabetes Care 2005;28:164-76
  10. Imai E, Haneda M, Chan JCN, Y et al. Reduction and residual proteinuria are therapeutic targets in type 2 diabetes with overt nephropathy: A post hoc analysis (ORIENT-proteinuria). Nephrol Dial Transplant 2013;28:2526-34
  11. Turner RC. The U.K. Prospective Diabetes Study: A review. Diabetes Care 1998;C35-8
  12. Tapp RJ, Shaw JE, Zimmet PZ, B et al. Albuminuria is evident in the early stages of diabetes onset: Results from the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab). Am J Kidney Dis 2004;44:792-8
  13. Meisinger C, Heier M, Landgraf R, et al. Albuminuria, cardiovascular risk factors and disease management in subjects with type 2 diabetes: A cross sectional study. BMC Health Serv Res 2008;8:1-7
  14. Afkhami-Ardekani M, Modarresi M, Amirchaghmaghi E. Prevalence of microalbuminuria and its risk factors in type 2 diabetic patients. Indian J Nephrol 2008;18:112
  15. Minoo F, Mahdavi-Mazdeh M, Abbasi M-R, Sohrabi S. Impact of the severity of obesity on microalbuminuria in obese normotensive nondiabetic individuals. J Ren Inj Prev 2015;4:34-8. 16.