SavedAdd your journal

Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 5

Platelet to lymphocyte ratio is associated with contrast induced nephropathy after primary percutaneous coronary intervention for ST-elevation myocardial infarction section

Gökhan ÇİCEK
Eser AÇIKGÖZ
Sadık Kadri AÇIKGÖZ
Pages
913–917
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Independent predictors of contrast induced nephropathy were investigated withlogistic regression analysis.Results: Patients with contrast induced nephropathy had significantly higher platelet to lymphocyte ratio (150.0 vs 119.1, p=0.001).In multivariate logistic regression analysis platelet to lymphocyte ratio (OR 1.100, 95% CI 1.050-1.130, p=0.033) was found as anindependent predictor of contrast induced nephropathy.Conclusion: Platelet to lymphocyte ratio may have a role to predict contrast induced nephropathy in patients undergoing primarypercutaneous coronary intervention for ST-elevation myocardial infarction.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Platelet to lyphocyte ratio is a novel inflammatory marker which is correlated with markers such as C-reactive protein andassociated with cardiovascular outcomes in coronary artery disease.
📊
Key Findings & Data:Association between platelet to lymphocyte ratio and contrast induced nephropathy developmentafter primary percutaneous coronary intervention with a diagnosis of ST-elevation myocardial infarction was evaluated in this study.Material and Methods: Data of 3352 consecutive patients who underwent primary percutaneous coronary intervention for STelevationmyocardial infarction were analysed.
💡
Conclusion & Impact:Independent predictors of contrast induced nephropathy were investigated withlogistic regression analysis.Results: Patients with contrast induced nephropathy had significantly higher platelet to lymphocyte ratio (150.0 vs 119.1, p=0.001).In multivariate logistic regression analysis platelet to lymphocyte ratio (OR 1.100, 95% CI 1.050-1.130, p=0.033) was found as anindependent predictor of contrast induced nephropathy.Conclusion: Platelet to lymphocyte ratio may have a role to predict contrast induced nephropathy in patients undergoing primarypercutaneous coronary intervention for ST-elevation myocardial infarction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Platelet to lyphocyte ratio is a novel inflammatory marker which is correlated with markers such as C-reactive protein andassociated with cardiovascular outcomes in coronary artery disease. Contrast iduced nephropathy is an important complication ofpecutaneous coronary intervention. Association between platelet to lymphocyte ratio and contrast induced nephropathy developmentafter primary percutaneous coronary intervention with a diagnosis of ST-elevation myocardial infarction was evaluated in this study.Material and Methods: Data of 3352 consecutive patients who underwent primary percutaneous coronary intervention for STelevationmyocardial infarction were analysed. Independent predictors of contrast induced nephropathy were investigated withlogistic regression analysis.Results: Patients with contrast induced nephropathy had significantly higher platelet to lymphocyte ratio (150.0 vs 119.1, p=0.001).In multivariate logistic regression analysis platelet to lymphocyte ratio (OR 1.100, 95% CI 1.050-1.130, p=0.033) was found as anindependent predictor of contrast induced nephropathy.Conclusion: Platelet to lymphocyte ratio may have a role to predict contrast induced nephropathy in patients undergoing primarypercutaneous coronary intervention for ST-elevation myocardial infarction.

🔖

Cite This Article

ÇİCEK, G., AÇIKGÖZ, E., AÇIKGÖZ, S. K. (2022). Platelet to lymphocyte ratio is associated with contrast induced nephropathy after primary percutaneous coronary intervention for ST-elevation myocardial infarction section. Annals of Medical Research, Cilt: 26 - Sayı: 5, 913–917. https://ajindex.com/articles/444597

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Mehran R, Aymong ED, Nikolsky E, et al. A simple risk score form prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol 2004;44:1393-9
  2. Senoo T, Motohiro M, Kamihata H, et al. Contrastinduced nephropathy in patients undergoing emergency percutaneous coronary intervention for acute coronary syndrome. Am J Cardiol 2010;105:624-8
  3. Goldfarb S, McCullough PA, McDermott J, et al. Contrastinduced acute kidney injury: specialty-specific protocols for interventional radiology, diagnostic computed tomography radiology, and interventional cardiology. Mayo Clin Proc 2009;84:170-9
  4. Finn WF. The clinical and renal consequences of contrastinduced nephropathy. Nephrol Dial Transplant 2006;21:i2- 10
  5. Cuddy E, Robertson S, Cross S, et al. Risks of coronary angiography. Lancet 2005;366:1825
  6. Gary T, Pichler M, Belaj K, et al. Platelet-to-lymphocyte ratio: a novel marker for critical limb ischemia in peripheral arterial occlusive disease patients. PLoS One 2013;8:676-88
  7. Azab B, Shah N, Akerman M, et al. Value of platelet/ lymphocyte ratio as a predictor of all-cause mortality after non- ST elevation myocardial infarction. J Thromb Thrombolysis 2012;34:326-34
  8. Kurtul A, Yarlioglues M, Murat SN, et al. Usefulness of the platelet-to lymphocyte ratio in predicting angiographic reflow after primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction. Am J Cardiol 2014;114:342-7
  9. Demircelik MB, Kurtul A, Ocek H, et al. Association between platelet-to-lymphocyte ratio and contrast-induced nephropathy in patients undergoing percutaneous coronary intervention for acute coronary syndrome. Cardiorenal Med 2015;5:96-104
  10. Kocas C, Yildiz A, Abaci O, et al. Platelet-to-Lymphocyte Ratio Predicts Contrast-Induced Nephropathy in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome. Angiology 2015;66:964-8
  11. Lazaros G, Tsiachris D, Tousoulis D, et al. In-hospital worsening renal function is an independent predictor of oneyear mortality in patients with acute myocardial infarction. Int J Cardiol 2012;155:97-101
  12. McCullough PA. Contrast-induced acute kidney injury. J Am Coll Cardiol 2008;51:1419-28
  13. Recio-Mayoral A, Chaparro M, Prado B, et al. The renoprotective effect of hydration with sodium bicarbonate plus N-acetylcysteine in patients undergoing emergency percutaneous coronary intervention: the RENO study. J