Journals / Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2001 / Cilt: 28 - Sayı: 3

Cytotoxicity of zinc oxide eugenol and paraformaldehyde containing sealers

Çinkooksit öjenol ve paraformaldehit içeren kanal patlarının sitotoksik etkilerinin değerlendirilmesi

Pages
265–269
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results revealed that both sealers had highly cytotoxic influence on the cells.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The purpose of this study was to determine the cytotoxicity of zinc oxide eugenol containing sealer Sultan and paraformaldehyde containing sealer Endomethasone.
📊
Key Findings & Data:Cytotoxic effects were assessed by viable cell counting under light microscope and with the MTT assay for mitochondrial enzyme activity after exposure on L929 cells at 24, 48 and 72 hours.
💡
Conclusion & Impact:Results revealed that both sealers had highly cytotoxic influence on the cells.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of this study was to determine the cytotoxicity of zinc oxide eugenol containing sealer Sultan and paraformaldehyde containing sealer Endomethasone. Cytotoxic effects were assessed by viable cell counting under light microscope and with the MTT assay for mitochondrial enzyme activity after exposure on L929 cells at 24, 48 and 72 hours. Approximately doubled amount of viable cells were determined in the control group after 72 h, whereas there were no viable cells for Sultan and Endomethasone groups at 72 h. Results revealed that both sealers had highly cytotoxic influence on the cells.

Özet

Bu çalışmada çinkooksit öjenol içerikli kanal patı Sultan ve paraformaldehit içerikli kanal patı Endomethasone'un sitotoksik etkilerinin incelenmesi amaçlanmıştır. Kanal patlarının sitotoksik etkileri L929 hücrelerinde 24, 48 ve 72. saatlerde ışık mikroskobunda canlı hücre sayımı yapılarak ve MTT testi ile mitokondrial enam aktivitesi değerlendirilerek incelenmiştir. Kontrol grubunda başlangıç hücre sayısı 72. saatte yaklaşık iki katına çıkarken, Sultan ve Endomethasone gruplarında ise 72. saatte canlı hücreye rastlanılmamıştır. Sonuçlar her iki kanal patının da hücreler üzerinde yüksek derecede toksik etkilerinin olduğunu ortaya koymuştur.

🔖

Cite This Article

ÖZTAN, D. M., ZAİMOĞLU, L., KALAYCI, A. (2022). Cytotoxicity of zinc oxide eugenol and paraformaldehyde containing sealers. Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 28 - Sayı: 3, 265–269. https://ajindex.com/articles/442329