Journals / Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2003 / Cilt: 30 - Sayı: 1

Antifungal effects of different irrigating solutions and calcium hydroxide containing disinfectants on C. albicans: An in vitro study

Farklı irigasyon solüsyonları ve kalsiyum hidroksitli dezenfektanların C. albicans üzerindeki antifungal etkilerinin in vitro olarak değerlendirilmesi

Pages
13–18
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The results of this study revealed that there were statistically significant differences between all tested irrigating solutions and calcium hydroxide containing disinfectants (p

📌 3 Key Takeaways

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Objective & Hypothesis:The purpose of this study was to evaluate the antifungal effects of different irrigating solutions and calcium hydroxide mixtures on C. albicans by agar diffusion test.
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Key Findings & Data:The irrigating solutions used were; 5% NaOCl, 2,5% NaOCl, 02% chlorhexidine gluconate and 5% NaOCl with KOH.
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Conclusion & Impact:The results of this study revealed that there were statistically significant differences between all tested irrigating solutions and calcium hydroxide containing disinfectants (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of this study was to evaluate the antifungal effects of different irrigating solutions and calcium hydroxide mixtures on C. albicans by agar diffusion test. The irrigating solutions used were; 5% NaOCl, 2,5% NaOCl, 02% chlorhexidine gluconate and 5% NaOCl with KOH. The sterile discs were soaked with irrigating solutions and placed onto previously seeded agar petri plates. Plates were incubated at 37°C for 48 h and the zones of inhibition were recorded and compared. In the second part of the study, calcium hydroxide powder was mixed with either distilled water, glycerine. 03% chlorhexidine gluconate or camphorated parachlorphenol. The mixtures were placed into the previously punched and seeded agar petri plates. The zones of inhibition were recorded after 72 h of incubation. Seven tests were performed for each material and t lie obtained data were analyzed statistically by using Kruskal-Wallis and multiple comparison tests. The results of this study revealed that there were statistically significant differences between all tested irrigating solutions and calcium hydroxide containing disinfectants (p

Özet

Bu çalışmada farklı irigasyon solüsyonları ve kalsiyum hidroksitti dezenfektanların C. albicans üzerindeki antifungal etkilerini agar diffüzyon yöntemi ile değerlendirmeyi amaçladık. Çalışmada irigasyon solüsyonu olarak; %5 NaOCl, %2,5 NaOCl, %0,2 klorheksidin glukonat ve KOH ilave edilmiş, %5 NaOCl kullanıldı. Steril disklere irigasyon solüsyonları emdirildikten sonra önceden ekim yapılmış plaklar üzerine yerleştirildi. Plaklar 37°C de 48 saat süre ile enkübe edildi. Meydana gelen inhibisyon zonları kaydedilerek karşılaştırıldı. Çalışmamızın ikinci bölümünde ise kalsiyum hidroksit tozu distile su, gliserin, %0,2 klorheksidin glukonat ve kafinin paraklorfenol ile karıştırıldı. Hazırlanan karışımlar önceden delikler açılmış ve ekimi yapılmış bulunan plaklara yerleştirildi. 72 saatlik enkübasyondan sonra meydana gelen inhibisyon zonları Ölçülüp kaydedildi. Testler her materyal için 7 kez tekrarlanarak, elde edilen veriler istatistiksel olarak Kruskal-Wallis ve çoklu karşılaştırma testleri ile değerlendirildi. Çalışmamızın sonuçlarına göre test edilen irigasyon solüsyonları ve kalsiyum hidroksitli dezenfektanlar arasındaki farklılıklar istatistiksel yönden anlamlı bulundu (p

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Cite This Article

SEVİMAY, S., MISIRLIGİL, A., ÖZTAN, D. M. (2022). Antifungal effects of different irrigating solutions and calcium hydroxide containing disinfectants on C. albicans: An in vitro study. Ankara Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 30 - Sayı: 1, 13–18. https://ajindex.com/articles/442264

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