Journals / Ankara Medical Journal / 2018 / Cilt: 18 - Sayı: 3

The Evaluation of Neutrophil/Lymphocyte Rates and Monocyte Counts in Patients with Acute Coronary Syndrome

Akut Koroner Sendromlu Hastalarda Nötrofil/Lenfosit Oranı ve Monosit Sayımının Değerlendirilmesi

Pages
345–354
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were significant differences between NLR’s (p = 0.009) and monocyte counts (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Acute coronary syndromes are at the top of all causes of death in the world and in our country.
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Key Findings & Data:Materials and Methods: The study was performed as a single center prospective study between 01.02.2017 and 31.07.2017 at the Emergency Medicine Clinic of a Training and Research Hospital in which the annual number of patients is 150,000.
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Conclusion & Impact:There were significant differences between NLR’s (p = 0.009) and monocyte counts (p
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Acute coronary syndromes are at the top of all causes of death in the world and in our country. In this study, we aimed to evaluate whether total blood count parameters have predictive value in clinical course of acute coronary syndromes. Materials and Methods: The study was performed as a single center prospective study between 01.02.2017 and 31.07.2017 at the Emergency Medicine Clinic of a Training and Research Hospital in which the annual number of patients is 150,000. Ethics approval was obtained from the Local Clinical Research Ethics Committee for the study. Demographic feature, total blood count parameter, neutrophil / lymphocyte ratio (NLR), GRACE risk score of the patients were recorded. Length of stay, in‐hospital mortality and 6‐month mortality of the patients were followed. Results: In this study, 77.27% of the patients were male and 22.73% were female. The mean age was 61 ± 12. There were significant differences between NLR’s (p = 0.009) and monocyte counts (p

Özet

Amaç: Akut koroner sendromlar, dünyada ve ülkemizde tüm ölüm sebepleri içerisinde en üst sırada yeralmaktadır. Bu çalışmada tam kan sayımı parametrelerinin akut koroner sendromların klinik seyrindeprediktif açıdan değerli olup olmadığını araştırmak amaçlanmıştır.Materyal ve Metot: Çalışma, yıllık hasta sayısı 150.000 olan bir Eğitim ve Araştırma Hastanesi Acil TıpKliniği’nde 01.02.2017‐31.07.2017 tarihleri arasında tek merkezli prospektif olarak gerçekleştirildi. Çalışmaiçin Lokal Klinik Araştırmalar Etik Kurulu’ndan etik onayı alındı. Hastaların demografik özellikleri, tamkan parametreleri, nötrofil / lenfosit oranı (NLR), GRACE risk skorları kayıt altına alındı. Hastalarınhastanede kalış süreleri, hastane içi mortaliteleri ve 6 aylık mortaliteleri takip edildi.Bulgular: Çalışmadaki hastaların %77,27’ ü erkek, %22,73’ si kadındı. Yaş ortalaması 61±12 idi. Tümgruplar içerisinde NLR değerleri (p=0,009), monosit sayıları (p

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Cite This Article

ŞENER, A., GÜNAYDIN, G. P., TANRIVERDİ, F., GÖKHAN, Ş., ÇELİK, G. K., AYDIN, İ. E. (2022). The Evaluation of Neutrophil/Lymphocyte Rates and Monocyte Counts in Patients with Acute Coronary Syndrome. Ankara Medical Journal, Cilt: 18 - Sayı: 3, 345–354. https://ajindex.com/articles/442181

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References (13)

  1. Wilkins E, Wilson L, Wickramasinghe K et al. European Cardiovascular Disease Statistics. 2017 edition. Brussels: Eur Heart Network; 2017:192
  2. Amsterdam EA, Wenger NK, Brindis RG, Casey DE, Ganiats TG, Holmes DR, et al. 2014 AHA/acc guideline for the management of patients with Non‐ST‐Elevation acute coronary syndromes: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014;64(24):e139–228
  3. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, et al. Third universal definition of myocardial infarction. Eur Heart J 2012;33(20):2551–67
  4. Janota T. Biochemical markers in the diagnosis of myocardial infarction. Cor Vasa 2014;56(4):1– 7
  5. Gillum RF, Mussolino ME, Madans JH. Counts of neutrophils, lymphocytes, and monocytes, cause‐specific mortality and coronary heart disease: The NHANES‐I epidemiologic follow‐up study. Ann Epidemiol 2005;15(4):266–71
  6. Horne BD, Anderson JL, John JM, Weaver A, Bair TL, Jensen KR, et al. Which white blood cell subtypes predict increased cardiovascular risk? J Am Coll Cardiol 2005;45(10):1638–43
  7. Gurm HS, Bhatt DL, Lincoff AM, Tcheng JE, Kereiakes DJ, Kleiman NS, et al. Impact of preprocedural white blood cell count on long term mortality after percutaneous coronary intervention: insights from the EPIC, EPILOG, and EPISTENT trials. Heart 2003;89(10):1200–4
  8. Kirtane AJ, Bui A, Murphy SA, Barron H V., Gibson CM. Association of peripheral neutrophilia with adverse angiographic outcomes in ST‐elevation myocardial infarction. Am J Cardiol 2004;93(5):532–6
  9. Dogan I, Karaman K, Sonmez B, Celik S, Turker O. Relationship between serum neutrophil count and infarct size in patients with acute myocardial infarction. Nucl Med Commun 2009;30(10):797–801
  10. Ommen SR, Gibbons RJ, Hodge DO, Thomson SP. Usefulness of the lymphocyte concentration as a prognostic marker in coronary artery disease. Am J Cardiol 1997;79(6):812–4
  11. Aghdaii N, Ferasatkish R, Mohammadzadeh Jouryabi A, Hamidi SH. Significance of preoperative total lymphocyte count as a prognostic criterion in adult cardiac surgery. Anesthesiol Pain Med 2014;4(3):e20331
  12. Núñez J, Sanchis J, Bodí V, et al. Therapeutic implications of low lymphocyte count in non‐ST segment elevation acute coronary syndromes. Eur J Intern Med 2009;20(8):768–74
  13. Muhmmed Suliman MAR, Bahnacy Juma AA, Ali Almadhani AA, Pathare AV, Alkindi SSA, Uwe Werner F. Predictive Value of Neutrophil