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Journals / Ankara Medical Journal / 2019 / Cilt: 19 - Sayı: 4

The Use of Ketamine in Trauma Patients

Travma Hastalarında Ketamin Kullanımı

Çağdaş YLDIRIM
Abdullah ALGIN
Nihat Müjdat HÖKENEK
Pages
776–783
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We aimed to investigate the frequency of ketamine use in clinical practice in trauma patients and whether it is the preferred agent in traumatic brain injuries and injuries with increased intraocular pressure (IOB) by reviewing the literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Trauma is one of the leading causes of death worldwide.
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Key Findings & Data:Because of pain respiratory rate can increase at them.
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Conclusion & Impact:We aimed to investigate the frequency of ketamine use in clinical practice in trauma patients and whether it is the preferred agent in traumatic brain injuries and injuries with increased intraocular pressure (IOB) by reviewing the literature.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Trauma is one of the leading causes of death worldwide. Stress response secondary to injury occurs at these patients. Because of pain respiratory rate can increase at them. In this regards airway management and hemodynamic stability are important parameters in trauma patients. Ketamine has noncompetitive antagonistic properties on the receptor of N-methyl-D aspartate (NMDA) and it can stimulate brainstem by noradrenalin reuptake inhibition. For that it can be used on monitorization of hemodynamic unstable trauma patients which monitorization is not suitable. We aimed to investigate the frequency of ketamine use in clinical practice in trauma patients and whether it is the preferred agent in traumatic brain injuries and injuries with increased intraocular pressure (IOB) by reviewing the literature.

Özet

Travma, dünya çapında ölümlerin önde gelen nedenlerinden biridir. Travma hastalarında meydana gelenakut ağrıya sekonder solunum zorluğu, yaralanmaya sekonder stres cevabı oluşabilir. Bu bakımdan travmahastalarında hava yolu yönetimi ve hemodinamik stabilite önemlidir. Ketamin, N-metil-D aspartate(NMDA) reseptörleri üzerinde nonkompetatif antagonistik özelliği ve beyin sapı uyarısı ile nöradrenalinreuptake inhibisyonu sağlar. Bu özelliği ile sempatik etki oluşturarak hemodinamik unstabil travmahastalarında ve monitorizasyonu sağlamanın uygun olmadığı şartlarda (Hastane öncesi afet, savaşyaralanmaları vb.) kullanımı açısından öncelikli ajan olarak literatürde sıkça vurgulanmaktadır. Travmahastalarında klinik pratikte ketaminin yeri, kullanım sıklığı, mortaliteyle doğrudan ilişkili Travmatik BeyinYaralanmalarında (TBY) ve intraokuler basınç (IOB) artışı ile giden yaralanmalarda geçmişten günümüzetercih edilen ajan haline gelmesini literatür taraması ile aydınlatmayı amaçladık.

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Cite This Article

YLDIRIM, Ç., ALGIN, A., HÖKENEK, N. M. (2022). The Use of Ketamine in Trauma Patients. Ankara Medical Journal, Cilt: 19 - Sayı: 4, 776–783. https://ajindex.com/articles/441891

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