Journals / Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2019 / Cilt: 52 - Sayı: 3

THE RELATIONSHIP BETWEEN VITAMIN D AND ULTRASONOGRAPHIC AND CYTOLOGICAL FINDINGS OF THYROID NODULES

TİROİD NODULLERİNDE ULTRASONOGRAFİK VE SİTOLOJİK BULGULAR İLE VİTAMİN D ARASINDAKİ İLİŞKİNİN DEĞERLENDİRİLMESİ

Pages
206–213
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this studywas to evaluate the relationship between vitamin D levels andultrasonographic, cytologic and postoperative pathologic data ofthe thyroid nodules.Methods: The study included 225 patients who underwentthyroidectomy after thyroid fine needle aspiration biopsy (FNAB) dueto the presence of thyroid nodules.The preoperative ultrasonographicfindings, the cytopathologic results obtained after FNAB andthyroidectomy operation and serum vitamin D levels were recorded.The relationship between vitamin D levels and ultrasonographic andcytologic findings of thyroid nodules was analyzed.Results: There was no statistically significant relationshipbetween vitamin D and ultrasonographic and histopathologicresults of thyroid nodules.ConclusIons: Our results showed that there was no relationshipbetween Vitamin D and ultrasonographic characteristics, biopsyand surgery results of thyroid nodules.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: There are reported associations between Vitamin Dand some cancers, but the relationship between vitamin D andthyroid cancers has not been fully evaluated.
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Key Findings & Data:The aim of this studywas to evaluate the relationship between vitamin D levels andultrasonographic, cytologic and postoperative pathologic data ofthe thyroid nodules.Methods: The study included 225 patients who underwentthyroidectomy after thyroid fine needle aspiration biopsy (FNAB) dueto the presence of thyroid nodules.The preoperative ultrasonographicfindings, the cytopathologic results obtained after FNAB andthyroidectomy operation and serum vitamin D levels were recorded.The relationship between vitamin D levels and ultrasonographic andcytologic findings of thyroid nodules was analyzed.Results: There was no statistically significant relationshipbetween vitamin D and ultrasonographic and histopathologicresults of thyroid nodules.ConclusIons: Our results showed that there was no relationshipbetween Vitamin D and ultrasonographic characteristics, biopsyand surgery results of thyroid nodules.
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Conclusion & Impact:We think that more extensivestudies are needed to assess the association between malignancyand large thyroid nodules associated with vitamin D deficiencies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: There are reported associations between Vitamin Dand some cancers, but the relationship between vitamin D andthyroid cancers has not been fully evaluated. The aim of this studywas to evaluate the relationship between vitamin D levels andultrasonographic, cytologic and postoperative pathologic data ofthe thyroid nodules.Methods: The study included 225 patients who underwentthyroidectomy after thyroid fine needle aspiration biopsy (FNAB) dueto the presence of thyroid nodules.The preoperative ultrasonographicfindings, the cytopathologic results obtained after FNAB andthyroidectomy operation and serum vitamin D levels were recorded.The relationship between vitamin D levels and ultrasonographic andcytologic findings of thyroid nodules was analyzed.Results: There was no statistically significant relationshipbetween vitamin D and ultrasonographic and histopathologicresults of thyroid nodules.ConclusIons: Our results showed that there was no relationshipbetween Vitamin D and ultrasonographic characteristics, biopsyand surgery results of thyroid nodules. However, when weretrospectively examined our results, we observed that very fewcases with malignancy were found to be benign in the preoperativeFNAB evaluation. These patients had low vitamin D levels and anodule size of more than 2.5 cm. We think that more extensivestudies are needed to assess the association between malignancyand large thyroid nodules associated with vitamin D deficiencies.

Özet

Amaç: Vitamin D ile bazı kanserler arasında bir ilişki olduğu bildirilmiş, ancak vitamin D ile tiroid kanserleri arasındaki ilişki tam olarak değerlendirilmemiştir. Bu çalışmanın amacı, D vitamini düzeyleri ile tiroid nodüllerinin ultrasonografik, sitolojik ve postoperative patolojik verileri arasındaki ilişkiyi değerlendirmektir. Yöntem: Çalışmamıza tiroid nodül varlığı nedeniyle tiroid ince iğne aspirasyon biyopsisi (TİİAB) sonrası tiroidektomi operasyonu uygulanan 225 hasta dahil edildi. Çalışmaya dahil edilen hastaların preoperatif ultrasonografik bulguları, TİİAB ve tiroidektomi operasyonu sonrası elde edilen sitopatolojik sonuçları ile serum vitamin D düzeyleri kaydedildi. Vitamin D düzeyleri ile tiroid nodüllerinin ultrasonografik ve sitolojik bulguları arasındaki ilişki analiz edildi. Sonuçlar: Vitamin D ile tiroid nodüllerinin ultrasonografik özellikleri, TİİAB ve cerrahi sonrası histopatolojik sonuçları arasında istatistiksel anlamlı ilişki saptanmadı. Tartışma: Sonuçlarımız D vitamini ile tiroid nodüllerinin ultrasonografik özellikleri, TİİAB ve cerrahi sonuçları arasında ilişki olmadığını göstermiştir. Bununla birlikte, sonuçlarımızı geriye dönük olarak incelediğimizde, operasyon sonrası malign saptanan çok az sayıda vakanın preoperatif TİİAB değerlendirmesinde benign saptandığını gözlemledik. Bu olgular vitamin D düzeyleri düşük ve nodül boyutu 2,5 cm'nin üzerinde olan olgulardı. Vitamin D eksikliğinin eşlik ettiği büyük tiroid nodülleri ile malignite arasındaki ilişkiyi değerlendirmek için daha kapsamlı çalışmalara ihtiyaç olduğunu düşünüyoruz.

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Cite This Article

Atalay, E., Tur, B. K., Kurt, G. K., Gürsoy, G. (2022). THE RELATIONSHIP BETWEEN VITAMIN D AND ULTRASONOGRAPHIC AND CYTOLOGICAL FINDINGS OF THYROID NODULES. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 52 - Sayı: 3, 206–213. https://ajindex.com/articles/441256

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