Journals / Anadolu Üniversitesi Bilim ve Teknoloji Dergisi :A-Uygulamalı Bilimler ve Mühendislik / 2017 / Cilt: 18 - Sayı: 2

IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)

Pages
439–455
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This active compound was isolated from aerial parts of T. abrotanifolium for the first time

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tanacetum L. (Asteraceae) species have been used by local people in folk medicine for centuries in Turkey to treat antipyretic, headache, tinnitus, dizziness and against difficulties in childbirth.
📊
Key Findings & Data:Successively fractionation and chromatographic process led to the isolation of luteolin-7-O-glucoside, an agent of anticancer, antimicrobial and antioxidant.
💡
Conclusion & Impact:This active compound was isolated from aerial parts of T. abrotanifolium for the first time
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Tanacetum L. (Asteraceae) species have been used by local people in folk medicine for centuries in Turkey to treat antipyretic, headache, tinnitus, dizziness and against difficulties in childbirth. We performed detailed biological activity screening tests of Tanacetum abrotanifolium, collected from its natural habitats in the eastern region of Turkey, for the first time. To obtain active compound from aerial parts of T. abrotanifolium by using chromatographic techniques, anticancer, antimicrobial and antioxidant assays were applied. Total phenol, flavonoid, β-carotene and lycopene contents were determined quantitatively. The isolation procedure was carried out successfully through thin layer and column chromatographies. Successively fractionation and chromatographic process led to the isolation of luteolin-7-O-glucoside, an agent of anticancer, antimicrobial and antioxidant. This active compound was isolated from aerial parts of T. abrotanifolium for the first time

🔖

Cite This Article

GEÇİBESLER, İ. H. (2022). IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE). Anadolu Üniversitesi Bilim ve Teknoloji Dergisi :A-Uygulamalı Bilimler ve Mühendislik, Cilt: 18 - Sayı: 2, 439–455. https://ajindex.com/articles/438282

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Rates SMK. Plants as source of drugs. Toxicon 2001; 39: 603-613
  2. Jassim SAA, & Naji MA. Novel antiviral agents: a medicinal plant perspective. J Applied Microbiol 2003; 95: 412-427
  3. Cos P, Vlietinck AJ, Vanden Berghe D, Maes L. Anti-infective potential of natural products: how to develop a stronger in vitro ‘proof-of concept’. J Ethnopharmacol 2006; 106: 290–302
  4. OBryan CA, Crandall PG, Ricke SC. Organic poultry pathogen control from farm to fork. Foodborne Pathog Dis 2008; 5: 709–720
  5. Janovska D, Kubikova K, Kokoska L. Screening for antimicrobial activity of some medicinal plant species of traditional Chinese medicine. Czech J Food Sci 2003; 21: 107-111
  6. Brown AM, Edwards CM, Davey MR, Power JB and Lowe KC. Effects of extracts of Tanacetum species on human polymorphonuclear leucocyte activity in vitro. Phytother Res 1997; 11: 479–484
  7. Jain NK, and Kulkarni SK. Antinociceptive and anti-inflammatory effects of Tanacetum parthenium L. extract in mice and rats. J Ethnopharmacol 1999; 68: 251– 259
  8. Williams C, Harborne JB, Geiger H, Robin J, and Hoult S. The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. Phytochemistry 1999; 51: 417–423
  9. Hwang DR, Wu YS, Chang CW, Lien TW, Chen WC, Tan UK, John TA, Hsua JTA, and Hsieh HP. Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system. Bioorg Med Chem 2006; 14: 83–91
  10. Jordan CT, The leukemic stem cell. Best Practice Res Clin Haematol 2007; 20: 13–18
  11. Gecibesler IH, Demirtas I, & Koçak A. Based on the quantity, temperature and time, the examination of variability in odorous components of Tanacetum abrotanifolium from Turkey: An exclusive gradient work. J Essent Oil Bear Pl 2015; 18: 840-843
  12. Polatoğlu K, Karakoç ÖC, Yücel YY, Demirci B, Gören, N, & Başer KHC. Composition, insecticidal activity and other biological activities of Tanacetum abrotanifolium Druce. essential oil. Ind Crop Prod 2015; 71: 7-14
  13. Gecibesler IH, Kocak A, & Demirtas I. Biological activities, phenolic profiles and essential oil components of Tanacetum cilicicum (Boiss.) Grierson. Nat Prod Res 2016; 30: 2850-2855
  14. Dewanto V, Wu X, Adom KK, and Liu RH. Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. J Agr Food Chem 2002; 50: 3010-3014
  15. Nagata M, and Yamashita I. Simple method for simultaneous determination of chlorophyll