AI Summary & Key Takeaways
AI InsightDiscussion and Conclusion: It was seen that less fluctuation was caused in the intraocular pressure by use of a 26-G compared to a 30-G needle during the injection of the same intravitreal drugs in demographically similar patients.
📌 3 Key Takeaways
Abstract
Aim: This study aimed to investigate the effects of injection needle diameter on the intraocular pressure in patients who underwent intravitreal injection. Materials and Methods: One hundred and seven eyes of 107 patients who underwent intravitreal aflibercept (IVA) injection for diabetic retinopathy or macular edema were included. Fifty-two eyes of the 52 patients for whom a 26-gauge (G) needle was used were designated as Group 1 and 55 eyes of the 55 patients for whom a 30-G needle was used as Group 2. Intraocular pressure (IOP) was measured before (BIOP) and after (AIOP) the blepharostat placement (AIOP) and 1 minute after the injection (EIOP). Results: There were 25 males and 27 females in Group 1 and 26 males and 29 females in Group 2 (p=0.93). The mean age was 56.40±7.62 years for Group 1 and 56.58±6.91 years for Group 2 (p=0.90). The mean BIOP and AIOP were respectively 18.56±3.91 mmHg and 21.94±4.27 mmHg for Group 1 while 18.10±3.80 mmHg and 20.63±4.91 mmHg for Group 2; and the differences were not statistically significant (p=0.63 and p=0.14, respectively). The mean EIOP was 34.84±16.46 mmHg for Group 1 and 47.05±10.02 mmHg for Group 2; and the difference was statistically significant (p=0.001). The mean EIOP–AIOP and EIOP–BIOP differences were respectively 12.86±17.63 mmHg and 15.80±16.65 mmHg for Group 1 (p=0.001) and 25.87±9.95 mmHg and 28.25±10.09 mmHg for Group 2 (p=0.001). Discussion and Conclusion: It was seen that less fluctuation was caused in the intraocular pressure by use of a 26-G compared to a 30-G needle during the injection of the same intravitreal drugs in demographically similar patients.
Özet
Amaç: İntravitreal enjeksiyon yapılan hastalarda enjeksiyon iğnesi çapının göz içi basıncına etkisiniincelemek amaçlanmıştır.Gereç ve Yöntemler: Diyabetik retinopati ve makula ödemi nedeniyle intravitreal aflibersept (IVA) enjeksiyonuuygulanan 107 hastanın 107 gözü çalışmaya dahil edildi. Yirmi altı gauge (G) iğne kullanılan52 hastanın 52 gözü Grup 1 olarak, 30 G iğne kullanılan 55 hastanın 55 gözü Grup 2 olarak değerlendirildi.Göz içi basıncı (GİB) blefarosta takılmadan önce (ÖGİB), blefarosta takıldıktan sonra (BGİB) veenjeksiyon sonrası 1. dakikada (EGİB) ölçüldü.Bulgular: Grup 1’de 25 erkek, 27 kadın, Grup 2’de 26 erkek, 29 kadın hasta mevcuttu (p=0,93). Yaş ortalamasıGrup 1’de 56,40±7,62 yıl, Grup 2’de 56,58±6,91 yıldı (p=0,90). Ortalama ÖGİB ve BGİB sırasıylaGrup 1’de 18,56±3,91 mmHg ve 21,94±4,27 mmHg, Grup 2’de 18,10±3,80 mmHg ve 20,63±4,91 mmHgidi; aradaki farklar istatistiksel olarak anlamlı değildi (sırasıyla, p=0,63 ve p=0,14). Ortalama EGİB değerleriise Grup 1’de 34,84±16,46 mmHg, Grup 2’de 47,05±10,02 mmHg olup aradaki fark istatistikselolarak anlamlıydı (p=0,001). EGİB–BGİB fark ortalaması Grup 1’de 12,86±17,63, Grup 2’de 25,87±9,95idi (p=0,001). EGİB–ÖGİB fark değerleri ortalaması ise Grup 1’de 15,80±16,65, Grup 2’de 28,25±10,09olarak tespit edildi (p=0,001) (Tablo 1).Tartışma ve Sonuç: Demografik benzerlikleri olan ve aynı intravitreal ilaçlar uygulanan hastalarda enjeksiyonun26 G iğne ile uygulanmasının 30 G iğne ile uygulanmasına göre daha az göz içi basıncıdeğişimi yaptığı görülmüştür.