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Journals / Anadolu Kliniği Tıp Bilimleri Dergisi / 2020 / Cilt: 25 - Sayı: 2

Two Women, One Baby: Mitochondrial Replacement Therapy from Medical, Ethical, and Legal Perspectives

İki Kadın Bir Bebek: Tıbbi, Etik ve Hukuki Perspektiflerden Mitokondri Değiştirme Terapisi

Hakan Ertin
Sevtap Metin
Adem Az
Pages
138–151
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This study deals with mitochondrial replacement therapy from medical, ethical, and legal perspectives.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The mitochondrion, found in almost all human cells, is the only organelle that contains DNA, except for the nucleus.
📊
Key Findings & Data:Mitochondrial gene defects lead to different diseases and syndromes with varying symptoms and severity. “Mitochondrial replacement therapy,” introduced in 2008, has been a milestone in the treatment of mitochondrial diseases, for which there is still no cure.
💡
Conclusion & Impact:This study deals with mitochondrial replacement therapy from medical, ethical, and legal perspectives.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

The mitochondrion, found in almost all human cells, is the only organelle that contains DNA, except for the nucleus. Mitochondrial gene defects lead to different diseases and syndromes with varying symptoms and severity. “Mitochondrial replacement therapy,” introduced in 2008, has been a milestone in the treatment of mitochondrial diseases, for which there is still no cure. Babies resulting from this procedure, colloquially called “three-parent babies,” are conceived with the use of assisted reproductive technologies and genetic material from two women and one man. This study deals with mitochondrial replacement therapy from medical, ethical, and legal perspectives.

Özet

Neredeyse tüm insan hücrelerinde bulunan mitokondri, çekirdek haricinde DNA içeren tek organeldir. Mitokondriyal gen defektleri semptomları ve şiddeti değişen çeşitli hastalık ve sendromlara neden olur. Mitokondriyal hastalıklarda bugün için kesin, küratif bir tedavi yoktur. Bu hastalıklarda dönüm noktası, 2008 yılında gündeme gelen “mitokondri değiştirme terapisi” olmuştur.Bu yöntemle dünyaya gelen bebekler (daha yaygın tabirle “üç ebeveynli bebekler”) üremeyeyardımcı teknolojiler ve de iki kadının ve bir erkeğin genetik materyalleri kullanılarak elde edilen bebeklerdir. Bu çalışmada mitokondri değiştirme terapisi tıbbi, etik ve hukuki yönlerden elealınmıştır.

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Cite This Article

Ertin, H., Metin, S., Az, A. (2022). Two Women, One Baby: Mitochondrial Replacement Therapy from Medical, Ethical, and Legal Perspectives. Anadolu Kliniği Tıp Bilimleri Dergisi, Cilt: 25 - Sayı: 2, 138–151. https://ajindex.com/articles/437671

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