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Journals / Ağrı / 2021 / Cilt: 33 - Sayı: 1

What is the optimal dose of intrathecal meperidine in open prostate surgery? A prospective double-blind randomized study

Açık prostat cerrahisinde intratekal meperidinin optimal dozu nedir? Bir prospektif çift-kör randomize çalışma

Fikret BAYAR
Özgür ÖZMEN
İlker İNCE
Mehmet AKSOY
Ayşenur DOSTBIL
Ömer DOYMUŞ
Mehmet CESUR
Journal
Ağrı
Pages
28–35
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The mean motor block scores at 20 minutes after the spinal injection were lower in Group I compared withthe other groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: This study was an analysis of the effect of different dosages of intrathecal meperidine (40 mg, 50 mg, 60 mg, and70 mg) on hemodynamic parameters, the duration of neural blockade, and the incidence of meperidine-related side effects inpatients who underwent an open prostatectomy.Methods: Sixty patients who underwent an open prostatectomy with combined spinal-epidural anesthesia were included.The patients were allocated to receive 1 of 4 different dosages of intrathecal meperidine (n=15 for each group): Group I: 40 mg,Group II: 50 mg, Group III: 60 mg, and Group IV: 70 mg.
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Key Findings & Data:The duration of the block procedure, surgery duration, highest sensoryblock level, and anesthetic complications were recorded and analyzed.Results: At 20 minutes after the spinal injection, the maximum sensory block level was T6 in Group I and II, and it was T5 inGroup III and IV.
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Conclusion & Impact:The mean motor block scores at 20 minutes after the spinal injection were lower in Group I compared withthe other groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study was an analysis of the effect of different dosages of intrathecal meperidine (40 mg, 50 mg, 60 mg, and70 mg) on hemodynamic parameters, the duration of neural blockade, and the incidence of meperidine-related side effects inpatients who underwent an open prostatectomy.Methods: Sixty patients who underwent an open prostatectomy with combined spinal-epidural anesthesia were included.The patients were allocated to receive 1 of 4 different dosages of intrathecal meperidine (n=15 for each group): Group I: 40 mg,Group II: 50 mg, Group III: 60 mg, and Group IV: 70 mg. The duration of the block procedure, surgery duration, highest sensoryblock level, and anesthetic complications were recorded and analyzed.Results: At 20 minutes after the spinal injection, the maximum sensory block level was T6 in Group I and II, and it was T5 inGroup III and IV. The mean motor block scores at 20 minutes after the spinal injection were lower in Group I compared withthe other groups (p

Özet

Amaç: Bu çalışmada; açık prostatektomi uygulanan hastalarda, farklı dozlarda intratekal meperidinin (40 mg, 50 mg, 60 mg ve 70 mg) hemodinamik parametreler, nöral blokaj süresi ve meperidine bağlı yan etki görülme sıklığı üzerindeki etkisini araştırdık. Gereç ve Yöntem: Kombine spinal epidural anestezi ile açık prostatektomi uygulanan 60 hasta çalışmaya alındı. Hastalar dört doz intratekal meperidinden birini almak üzere (her grup için n=15) sahip olmak üzere ayrıldı: Grup I: 40 mg, Grup II: 50 mg, Grup III: 60 mg, Grup IV: 70 mg. Blok işleminin süresi, ameliyat süresi, en yüksek duyusal blok düzeyi ve anestezik komplikasyonlar kaydedildi. Bulgular: Spinal enjeksiyondan 20 dakika sonra, grup I ve II’de maksimum duyusal blok seviyesi T6 idi ve grup III ve IV’de T5 idi. Spinal enjeksiyondan 20 dakika sonra ortalama motor blok skorları grup I’de diğer gruplara göre daha düşük olarak bulundu (hepsi için p

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Cite This Article

BAYAR, F., ÖZMEN, Ö., İNCE, İ., AKSOY, M., DOSTBIL, A., DOYMUŞ, Ö., CESUR, M. (2022). What is the optimal dose of intrathecal meperidine in open prostate surgery? A prospective double-blind randomized study. Ağrı, Cilt: 33 - Sayı: 1, 28–35. https://ajindex.com/articles/430555

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