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Journals / Acta Veterinaria Eurasia / 2018 / Cilt: 44 - Sayı: 2

SOD, CAT, TBARS, and TNF-α Concentrations in Uterine Tissues of Bitches with Pyometra and Dioestrus Bitches

Pyometralı ve Sağlıklı Diöstrustaki Köpeklerde uterus SOD, CAT, TBARS ve TNF-α Konsantrasyonları

Tuğba Seval Fatma TOYDEMİR KARABULUT
Pages
59–62
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

SOD and CAT enzymes were found significantly higherin uterine tissues of dioestrus group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Decreased antioxidant levels may be a cause of many diseases.Pus accumulation in the uterus literally called pyometra andgenerally occurs in median or late life span of bitches.
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Key Findings & Data:For this purpose, bitches with pyometra (n=27),and healthy bitches in dioestrus (n=8) included in the studyand both of the groups went under ovariohysterectomy operation.
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Conclusion & Impact:SOD and CAT enzymes were found significantly higherin uterine tissues of dioestrus group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Decreased antioxidant levels may be a cause of many diseases.Pus accumulation in the uterus literally called pyometra andgenerally occurs in median or late life span of bitches. The objective of the study was to evaluate the concentrations of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT),oxidative stress parameter-thiobarbituric acid-reactive substances (TBARS) and inflammatory mediator, tumour necrosisfactor alpha (TNF-α) in uterine tissues of bitches with and without pyometra. For this purpose, bitches with pyometra (n=27),and healthy bitches in dioestrus (n=8) included in the studyand both of the groups went under ovariohysterectomy operation. SOD and CAT enzymes were found significantly higherin uterine tissues of dioestrus group (p

Özet

Azalmış antioksidan seviyeleri pek çok hastalığın sebebi olabilmektedir. Pyometra orta yaşlı ve yaşlı kısırlaştırılmamış dişi köpeklerde görülen uterusun irinle dolmasıyla karakterize bir hastalıktır. Çalışmamızın amacı oksidatif stres parametrelerinden süperoksit dizmutaz (SOD), katalaz (CAT), tiyobarbitürik asid maddeleri (TBARS) ve enflamatorik mediyatörlerden tümör nekroz faktörünün (TNF-alpha) pyometralı köpek uterusunda ve sağlıklı köpek uterusunda bakıp karşılaştırarak gruplar arasındaki olabilecek variyasyonu tespit etmekti. Bu amaçla, pyometralı köpekler (n=27) ve diöstrustaki sağlıklı köpekler (n=8) çalışmaya dahil edildi ve her iki gruptaki köpeklere de ovariyohisterektomi operasyonu uygulandı. Uterusta SOD ve CAT seviyeleri kontrol grubunda önemli oranda yüksek bulundu (sırasıyla, p

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Cite This Article

KARABULUT, T. S. F. T. (2022). SOD, CAT, TBARS, and TNF-α Concentrations in Uterine Tissues of Bitches with Pyometra and Dioestrus Bitches. Acta Veterinaria Eurasia, Cilt: 44 - Sayı: 2, 59–62. https://ajindex.com/articles/428052

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References (12)

  1. Agarwal, A., Gupta, S., Sharma, R.K., 2005. Role of oxidative stress in female reproduction. Reproductive Biology and Endocrinology 3, 28. Al-Gubory, K.H., Fowler, P.A., Garrel, C., 2010. The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes. The International Journal of Biochemistry & Cell Biology 42, 1634–1650.
  2. Bedaiwy, M.A., Falcone, T., 2003. Peritoneal fluid environment in endometriosis. Clinicopathological implications. Minerva Ginecologica 55, 333-345.
  3. Burton, G.J., Jauniaux E., 2011. Oxidative stress. Best Practice & Research Clinical Obstetrics and Gynaecology 25, 287–299.
  4. Ercan, N., Fidancı, U.R., 2012. Piyodermalı köpeklerde idrarda 8-hidroksi-2’-deoksiguanozin (8-OHdG) düzeyleri. Ankara Üniversitesi Veteriner Fakültesi Dergisi 59, 163-168.
  5. Gupta, S., Agarwal, A., Banerjee, J., Alvarez, J., 2007. The role of oxidative stress in spontaneous abortion and recurrent pregnancy loss: a systematic review. Obstetrical and Gynecological Survey 62, 335–347.
  6. Jain, S., Saxena, D., Kumar, P.G., Koide, S.S., Laloraya, M., 1999. Effect of estradiol and selected antiestrogens on Pro- and Antioxidant pathways in mammalian uterus. Contraception 60, 111–118.
  7. Jozwik, M., Wolczynski, S., Szamatowicz, M., 1999. Oxidative stress markers in preovulatory follicular fluid in humans. Molecular Human Reproduction 5, 409-413.
  8. Karlsson, I., Hagman, R., Johannisson, A., Wang, L., Karlstam, E., Wernersson, S., 2012. Cytokines as immunological markers for systemic inflammation in dogs with pyometra. Reproduction In Domestic Animals 47, 337–341.
  9. Laloraya, M., Kumar, G.P., Laloraya, M.M., 1990. Changes in the superoxide radical and superoxide dismutase levels in the uterus of Rattus norvegicus during the estrous cycle and a possible role for superoxide radical in uterine oedema and cell proliferation at proestrus. Biochemistry and Cell Biology 69, 313-316.
  10. Mir, F., Fontaine, E., Albaric, O., Greer, M., Vannier, F., Schlafer, D.H., Fontbonne, A., 2013. Findings in uterine biopsies obtained by laparotomy from bitches with unexplained infertility or pregnancy loss: An observational study. Theriogenology 79, 312–322.
  11. Mohebbi-Fani, M., Ansari-Lar, M., Nazifi, S., Abbasi, F., Shabbooe, Z., 2016. Oxidative status and acute phase response in post-transition early- and mid-lactation Holstein cows and their correlations with some performance records. İstanbul Üniversitesi Veteriner Fakültesi Dergisi 42, 65-73.
  12. Nakano, T., Oka, K., Taniguchi