AI Summary & Key Takeaways
AI InsightThere were significant association between neutrophil tolym-phocyte ratio > 3.17 and macrovascular invasion, the tumor number> 3, thetumor size> 5 cm, Child-Turcot-Pugh score, Model for End-stage Liver DiseaseSodium score, C-reactive protein and blood sodium level (p: 0.005, p: 0.009, p 3.17 was an independent predictor oftumor size> 5 cm and hyponatremia in patients with hepatocellular carcinoma (p:0.010, p: 0.012, respectively).Conclusions: The value of blood neutrophil to lymphocyte ratio at the time of diagnosis in patients with hepatocellular carcinoma was a good predictor of tumor sizeand grade of disease.
📌 3 Key Takeaways
Abstract
Aim: We aimed to show the relationship between blood neutrophil to lymphocyteratio that is systemic inflammatory marker and tumor s ize, tumor number, macrovascular invasion at the time of diagnosis in patients with hepatocellular carcinoma.Methods: A total 48 patients diagnosed with hepatocellular carcinoma were includedin our study. The patients were divided into two groups according to themedian neutrophil to lymphocyte ratio.Results: A total of 48 patients (11 female, 37 male) were included in our study.The mean age of the patients were 67.18±9.51 years-old. The median neutrophil tolym-phocyte ratio was 3.17. There were significant association between neutrophil tolym-phocyte ratio > 3.17 and macrovascular invasion, the tumor number> 3, thetumor size> 5 cm, Child-Turcot-Pugh score, Model for End-stage Liver DiseaseSodium score, C-reactive protein and blood sodium level (p: 0.005, p: 0.009, p 3.17 was an independent predictor oftumor size> 5 cm and hyponatremia in patients with hepatocellular carcinoma (p:0.010, p: 0.012, respectively).Conclusions: The value of blood neutrophil to lymphocyte ratio at the time of diagnosis in patients with hepatocellular carcinoma was a good predictor of tumor sizeand grade of disease.
Özet
Amaç: Hepatosellüler Karsinomu olan hastalarda tanı anındaki tümör boyutu, tümör sayısı ve makrovasküler invazyon ile kan nötrofil lenfosit oranı arasındaki ilişkiyi göstermeyi amaçladık. Hastalar ve Method: Çalışmaya toplam 48 hepatosellüler karsinomalı hasta dahil edildi. Hastalar ortalama nötrofil lenfosit oranına göre ikiye bölündü. Bulgular: Toplam 48 hastanın 11’i kadın, 37’si erkek idi. Hastaların ortalama yaşı 67,18±9,51 idi. Ortalama nötrofil lenfosit oranı 3,17 idi. Nötrofil lenfosit oranı (NLR)>3,17 olan hastalarda makrovasküler invazyon, tümör sayısının>3, tümör boyutu>5 cm, Child-Turcot-Pugh skor, Model for End-stage Liver Disease- Sodyum skor, C-reaktif protein and kan sodyum seviyesi ile arasında istatistiksel olarak anlamlı birliktelik izlendi (p: 0.005, p: 0.009, p 3.17 olması tumor boyutu> 5 cm and hiponatreminin bağımsız bir belirteci olduğunu gösterdi (p: 0.010, p: 0.012, sırasıyla). Sonuç: Hepatosellüler karsinomalı hastalarda tanı anındaki kan nötrofil lenfosit oranının değeri, tümör boyutunun ve hastalık evresinin iyi bir belirtecidir.