Journals / Acta Medica Alanya / 2019 / Cilt: 3 - Sayı: 1

Clinical presentation and metabolic features of urinary stones in children: Single center experience

Çocuklarda üriner sistem taşı klinik görünümü ve metabolik özellikleri: Tek merkez deneyimi

Pages
59–66
Publication Date
2022-09-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We believe that the detection and treatment of metabolic causes, reduce the stone recurrence, the requirement for surgical procedures, and ESRD in affected children.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: We aimed to evaluate the demographic characteristics, metabolic etiology, and response to treatment of children who admitted to our hospital with an urinary stone disease (USD) in our study.
📊
Key Findings & Data:Patients and Method: The medical records of 259 patients who had been diagnosed with USD, between 01/04/2017-31/03/2018 were reviewed retrospectively.
💡
Conclusion & Impact:We believe that the detection and treatment of metabolic causes, reduce the stone recurrence, the requirement for surgical procedures, and ESRD in affected children.
🔬Design:Review & Systematic Survey
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: We aimed to evaluate the demographic characteristics, metabolic etiology, and response to treatment of children who admitted to our hospital with an urinary stone disease (USD) in our study. Patients and Method: The medical records of 259 patients who had been diagnosed with USD, between 01/04/2017-31/03/2018 were reviewed retrospectively. Results: The most common presenting symptoms of the patients were USD detected by ultrasonography performed for other reasons (n: 100, 38.6%). 52 of the patients (20.1%) had pyuria and urine culture positivity. Hematuria was detected in 31 (11.2%) patients. Hypocitraturia (38/82) 46.3%, hypomagnesuria (22/116) 13.2%, hypercalciuria (28/225) 12.4%, hyperuricosuria (17/219) 7.7%, hyperoxaluria (4/76) 5.2% was found in cases. Serum vitamin D levels were high in 5.8% of cases (15/259). The most common localization of stone was lower kidney pole (38.2%). Medical treatment was given to 92 (35.5%) patients while extracorporeal shock wave lithotripsy (ESWL) was performed in 34 (13.12%) patients and other surgical procedures were performed in 9 (3.74%) cases. Concurrent medical and surgical treatment was performed in 17 patients. The median follow-up period of 199 cases under followed-up was 3 months (1-12 months). In the last follow-up, 142 (71.35%) of the patients showed improvement, while 36 (18.05%) had no change in stone size, and 21 (10.6%) had an increase in stone size. Conclusion: Currently, USD is not rare in children with increasing in diagnostic methods. We believe that the detection and treatment of metabolic causes, reduce the stone recurrence, the requirement for surgical procedures, and ESRD in affected children.

Özet

Amaç: Çalışmamızda hastanemize üriner sistem taş hastalığı (ÜSTH) saptanarakbaşvuran çocukların demografik özellikleri, metabolik etyolojileri ve tedaviye yanıtlarının değerlendirilmesi amaçlanmıştır.Hastalar ve Yöntem: 01/04/2017-31/03/2018 arası Çocuk Nefroloji-Üroloji kliniklerine başvuran ÜSTH tanısı konulmuş 259 hastanın kayıtları retrospektif olarak incelenmiştir.Bulgular: Olguların en fazla başvuru şikayeti, başka nedenlerle yapılan ultrasonografide saptanan ÜSTH (n:100, %38.6) idi. Olguların 52’sinde (%20.1) piyüri veidrar kültüründe üreme vardı. Hematüri 31 (%11.2) olguda saptandı. Hipositratüri(38/82) %46.3, hipomagnezüri (22/116) %13.2, hiperkalsiüri (28/225) %12.4, hiperürikozüri (17/219) %7.7, hiperokzalüri (4/76) %5.2 olguda tespit edildi. Serum vitamin D düzeyi olguların (15/259) %5.8’inde yüksekti. Taş yerleşimi en sık böbrekalt polünde (%38.2) saptandı. Medikal tedavi verilen olgu 92 (%35.5), vücut dışı şokdalga litotripsi (ESWL) yapılan 34 olgu (%13.12), diğer cerrahi girişimlerin yapıldığıolgular ise 9 (%3.74) idi. 17 olguya eş zamanlı medikal ve cerrahi tedavi uygulandı.Takibe devam eden 199 olgunun ortanca takip süresi 3 ay (en kısa 1 ay en uzun 12ay) idi. Son takiplerinde hastaların 142’sinde (%71.35) iyileşme görülürken, 36’sında(%18.05) taş boyutunda değişiklik saptanmadı, 21’inde (%10.6) ise taş boyutundaartış mevcuttu.Sonuç: Günümüzde tanısal yöntemlerin artması ile çocuklarda ÜSTH’nın nadir olmadığı görülmektedir. Metabolik nedenin saptanması ve tedavisi; taş tekrarını, cerrahi işlem gereksinimini ve etkilenmiş çocuklarda SDBY azalttığı kanaatindeyiz.

🔖

Cite This Article

ATMIŞ, B., GEMİCİ, A., ERGÜN, R. (2022). Clinical presentation and metabolic features of urinary stones in children: Single center experience. Acta Medica Alanya, Cilt: 3 - Sayı: 1, 59–66. https://ajindex.com/articles/425857

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Alpay H, Ozen A, Gokce I, Biyikli N. Clinical and metabolic features of urolithiasis and microlithiasis in children. Pediatr Nephrol. 2009
  2. 24(11):2203-9. PMID: 1960319 2. Milliner DS. Urolithiasis. In: Avner ED, Harman WE, Niavdet P. Pediatric Nephrology (5th ed). Philadelphia: Lippincott Williams &Wilkins, 2004. p1091-1112. 3. Rizvi SA, Naqvi SA, Hussain Z, Hashmi A, Hussain M, Zafar MN, et al. Pediatric urolithiasis: developing nation perspectives. J Urol. 2002
  3. PMID: 12352448 4. Elder JS. Urinary lithiasis. In: Behrman ER, Kliegman MR, Jenson BH (eds). Nelson Textbook of Pediatrics, 16th ed. Philadelphia: Saunders, 2000. p1655-8. 5. Spivacow FR, Negri AL, del Valle EE, Calviño I, Fradinger E, Zanchetta JR. Metabolic risk factors in children with kidney stone disease. Pediatr Nephrol. 2008
  4. PMID: 18324422 6. Sirin A, Emre S, Alpay H, Nayir A, Bilge I, Tanman F. Etiology of chronic renal failure in Turkish children. Pediatr Nephrol. 1995
  5. PMID: 8580006 7. Polito C, Cioce F, La Manna A, Maiello R, Di Toro R. Renal calyceal microlithiasis: clinical presentation may precede sonographic evidence. Clin Pediatr (Phila). 1999
  6. 38(9):521- 4. PMID: 10500884 8. Demir F, Yavuz S, Kıyak A, Aydoğan G, Korkmaz O, Sarı F.Infantil Urolithiasis: A Single Center Experience. İKSST Dergisi 2014
  7. 6(3):137-41. DOI: 10.5222/iksst.2014.137 9. Düşünsel R, Baştuğ F. Çocuk Nefroloji El Kitabı, Klinik Pratik Yaklaşımlar Editör: Düşünsel R. 2018. p.186 10. Hoppe B, Leumann E, Milliner DS. Urolithiasis and nephrocalcinosis in childhood. In: DF Geary, Schaefer F (eds). Comprehensive Pediatric Nephrology. 1st ed. Philadelphia: Elsevier, 2008. p499-525. 11. Sarica K. Pediatric urolithiasis: etiology, specific pathogenesis and medical treatment. Urol Res. 2006
  8. PMID: 16432692 12. Melek E, Gülleroğlu KŞ, Bayrakçı US. Clinical and Metabolic features of Kidney Stones in Children. Türkiye Çocuk HastDerg/Turkish J Pediatr Dis/ 2016
  9. DOI: 10.12956/tjpd.2015.168 13. Hoppe B, Kemper MJ. Diagnostic examination of the child with urolithiasis or nephrocalcinosis. Pediatr Nephrol 2010
  10. 403–13. PMID: 19104842 14. Bak M, Ural R, Agin H, Serdaroglu E, Calkavur S. The metabolic etiology of urolithiasis in Turkish children. Int Urol Nephrol 2009
  11. PMID: 19184515 15. Gürgöze MK, Sarı MY. Results of medical treatment and metabolic risk factors in children with urolithiasis. Pediatr Nephrol 2011
  12. PMID: 21340610 16. Kara A, Gurgoze MK, Gozut