SavedAdd your journal

Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2010 / Cilt: 18 - Sayı: 3

Surgical treatment of supravalvular aortic stenosis and coronary artery disease in a young patient with familial hypercholesterolemia

Ailesel hiperkolesterolemili genç hastada supravalvüler aortik stenoz ve koroner arter hastalığının cerrahi tedavisi

Kaan KIRALİ
İlker MATARACI
Rahmi ZEYBEK
Cüneyt KELEŞ
Murat Bülent RABUŞ
Pages
217–219
Publication Date
2022-09-02
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, we present a familial hypercholesterolemia case characterized by xanthomas and a quite early onset diffuse atherosclerosis resulting in supravalvular stenosis and coronary artery disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hypercholesterolemia is a dyslipidemic syndrome which is characterized by an increase in total cholesterol and low density lipoprotein cholesterol levels.
📊
Key Findings & Data:Familial hypercholesterolemia appears during childhood resulting in coronary artery disease between 30 and 50 years of age.
💡
Conclusion & Impact:In this study, we present a familial hypercholesterolemia case characterized by xanthomas and a quite early onset diffuse atherosclerosis resulting in supravalvular stenosis and coronary artery disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hypercholesterolemia is a dyslipidemic syndrome which is characterized by an increase in total cholesterol and low density lipoprotein cholesterol levels. Familial hypercholesterolemia appears during childhood resulting in coronary artery disease between 30 and 50 years of age. In this study, we present a familial hypercholesterolemia case characterized by xanthomas and a quite early onset diffuse atherosclerosis resulting in supravalvular stenosis and coronary artery disease.

Özet

Hiperkolesterolemi total kolesterol ve düşük yoğunluklu lipoprotein kolesterol düzeylerinde artışla karakterize bir dislipidemik sendromdur. Ailesel hiperkolesterolemi çocuklukta başlar ve 30-50 yaş arasında koroner arter hastalığı ile sonuçlanır. Bu yazıda oldukça erken bir yaşta başlayan, supravalvüler darlığa ve koroner arter hastalığına neden olan yaygın ateroskleroz ve ksantomalarla seyreden bir ailesel hiperkolesterolemi olgusu sunuldu.

🔖

Cite This Article

KIRALİ, K., MATARACI, İ., ZEYBEK, R., KELEŞ, C., RABUŞ, M. B. (2022). Surgical treatment of supravalvular aortic stenosis and coronary artery disease in a young patient with familial hypercholesterolemia. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 18 - Sayı: 3, 217–219. https://ajindex.com/articles/424973

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Stone NH, Levy Rl, Fredrickson DS, Verier J. Coronary artery disease in 116 kindred with familial type II hyperlipoproteinemia. Circulation 1974;49:476-88
  2. Mitchell AG, Raphael MJ, Thompson GR, Oakley CM. Cardiovascular abnormality in homozygous familial hypercholesterolemia. Brit Heart J 1977;39:342
  3. Mabuchi H, Tatami R, Haba T, Ueda K, Ueda R, Kametani T, et al. Homozygous familial hypercholesterolemia in Japan. Am J Med 1978;65:290-7
  4. Allen JM, Thompson GR, Myant NB, Steiner R, Oakley CM. Cadiovascular complications of homozygous familial hypercholesterolaemia. Br Heart J 1980;44:361-8
  5. Forman MB, Kinsley RH, Du Plessis JP, Dansky R, Milner S, Levin SE. Surgical correction of combined supravalvular and valvular aortic stenosis in homozygous familial hypercholesterolaemia. S Afr Med J 1982;61:579-82
  6. Thompson GR, Miller JP, Breslow JL. Improved survival of patients with homozygous familial hypercholesterolaemia treated with plasma exchange. Br Med J (Clin Res Ed) 1985; 291:1671-3
  7. Illingworth DR. Management of hyperlipidemia: goals for the prevention of atherosclerosis. Clin Invest Med 1990; 13:211-8.