SavedAdd your journal

Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2013 / Cilt: 21 - Sayı: 4

Akut lenfoblastik lösemili bir hastada aspergillus endokarditi

Aspergillus endocarditis in a patient with acute lymphoblastic leukemia

Buğra HARMANDAR
Serap ŞİMŞEK
Ahmet ŞAŞMAZEL
İlker Kemal YÜCEL
Numan Ali AYDEMİR
Ali Rıza KARACI
Pages
1067–1070
Publication Date
2022-09-02
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, he died due to possible intracerebralabscesses during follow-up.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aspergillus endocarditis is a life-threatening condition.Establishment of the diagnosis and treatment remainhighly challenging.
📊
Key Findings & Data:In this article, we report a 5.5-year-old boy with acute lymphoblastic leukemia in whomimmunosuppression-related Aspergillus endocarditisdeveloped.
💡
Conclusion & Impact:However, he died due to possible intracerebralabscesses during follow-up.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aspergillus endocarditis is a life-threatening condition.Establishment of the diagnosis and treatment remainhighly challenging. Aspergillus endocarditis should besuspected in immunocompromised patients with negativeblood cultures and vegetation on echocardiography.Definitive diagnosis is based on tissue histology andculture. The best treatment approach requires aggressivesurgical debridement in combination with prolongedantifungal therapy. In this article, we report a 5.5-year-old boy with acute lymphoblastic leukemia in whomimmunosuppression-related Aspergillus endocarditisdeveloped. The patient underwent a Ross operation andexcision of a large vegetation in the left ventricular outflowtract. However, he died due to possible intracerebralabscesses during follow-up.

Özet

Aspergillus endokarditi hayati tehlike oluşturan bir durumdur. Tanı ve tedavisi oldukça zordur. İmmün sistemi baskılanmış hastalarda alınan kan kültürlerinin negatif olması ve ekokardiyografide vejetasyon görülmesi durumunda Aspergillus endokarditinden şüphelenilmelidir. Bu hastalarda kesin tanı, doku histolojisi ve kültürü ile yapılır. Tedavide en iyi yaklaşım agresifcerrahi debridmanı ile birlikte uzun süreli antifungaltedavi uygulanmasıdır. Bu makalede immün yetersizlik nedeniyle Aspergillus endokarditi gelişen akut lenfoblastik lösemili 5.5 yaşında bir erkek olgu sunuldu. HastayaRoss ameliyatı ile birlikte sol ventrikül çıkım yolundakigeniş vejetasyonun ekzisyonu uygulandı. Ancak, takip süresinde gelişen muhtemel intraserebral apselere bağlıolarak hasta kaybedildi.

🔖

Cite This Article

HARMANDAR, B., ŞİMŞEK, S., ŞAŞMAZEL, A., YÜCEL, İ. K., AYDEMİR, N. A., KARACI, A. R. (2022). Akut lenfoblastik lösemili bir hastada aspergillus endokarditi. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 21 - Sayı: 4, 1067–1070. https://ajindex.com/articles/424619

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. El-Hamamsy I, Dürrleman N, Stevens LM, Cartier R, Pellerin M, Perrault LP, et al. A cluster of cases of Aspergillus endocarditis after cardiac surgery. Ann Thorac Surg 2004;77:2184-6
  2. Hoen B, Alla F, Selton-Suty C, Béguinot I, Bouvet A, Briançon S, et al. Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA 2002;288:75-81
  3. Pierrotti LC, Baddour LM. Fungal endocarditis, 1995-2000. Chest 2002;122:302-10
  4. McCormack J, Pollard J. Aspergillus endocarditis 2003- 2009. Med Mycol 2011;49 Suppl 1:S30-4
  5. Ellis ME, Al-Abdely H, Sandridge A, Greer W, Ventura W. Fungal endocarditis: evidence in the world literature, 1965- 1995. Clin Infect Dis 2001;32:50-62
  6. Escande W, Fayad G, Modine T, Verbrugge E, Koussa M, Senneville E, et al. Culture of a prosthetic valve excised for streptococcal endocarditis positive for Aspergillus fumigatus 20 years after previous A fumigatus endocarditis. Ann Thorac Surg 2011;91:e92-3
  7. Woods GL, Wood RP, Shaw BW Jr. Aspergillus endocarditis in patients without prior cardiovascular surgery: report of a case in a liver transplant recipient and review. Rev Infect Dis 1989;11:263-72
  8. Barst RJ, Prince AS, Neu HC. Aspergillus endocarditis in children: case report and review of the literature. Pediatrics 1981;68:73-8
  9. Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis 2008;46:327-60
  10. Nikolousis E, Velangi M. Two cases of aspergillus endocarditis in non neutropenic children on chemotherapy for acute lymphoblastic leukaemia. Hematol Rep 2011;3:e7.