Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2013 / Cilt: 21 - Sayı: 4

Majör vasküler cerrahi yapılan hastalarda ameliyat öncesi nötrofil-lenfosit oranı ve trombosit-lenfosit oranının değerlendirilmesi

Evaluation of preoperative neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in patients undergoing major vascular surgery

Pages
930–935
Publication Date
2022-09-02
DOI
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The proportion ofdiabetic patients was significantly higher for patients withNLR ≥5 (63.7%; p= 0.000) and PLR ≥200 (%53.8; p=0.003).Conclusion: Our study results showed that increased levelsof NLR and PLR were directly correlated with mortalityand inversely correlated with survival in the postoperativeperiod and that diabetic patients were under a higher risk.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: This study aims to examine whetherpreoperative neutrophil-lymphocyte ratio (NLR) andplatelet-lymphocyte ratio (PLR) had a preoperativeprognostic role and its association with survival in patientsundergoing major vascular surgery.Methods: Between June 2005 and December 2012, 838consecutive patients (593 males, 245 females; mean age 63years; range, 10 to 99 years) who underwent major vascularsurgery in our clinic were included.
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Key Findings & Data:The NLR and PLRwere determined by dividing the absolute neutrophil andplatelet count by the absolute lymphocyte count.Results: The mean mortality risk was 2.85 (range 1.67-4.87) in patients with a NLR of ≥5 and 3.76 (range 2.31- 6.12) in patients with a PLR of ≥200.
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Conclusion & Impact:The proportion ofdiabetic patients was significantly higher for patients withNLR ≥5 (63.7%; p= 0.000) and PLR ≥200 (%53.8; p=0.003).Conclusion: Our study results showed that increased levelsof NLR and PLR were directly correlated with mortalityand inversely correlated with survival in the postoperativeperiod and that diabetic patients were under a higher risk.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: This study aims to examine whetherpreoperative neutrophil-lymphocyte ratio (NLR) andplatelet-lymphocyte ratio (PLR) had a preoperativeprognostic role and its association with survival in patientsundergoing major vascular surgery.Methods: Between June 2005 and December 2012, 838consecutive patients (593 males, 245 females; mean age 63years; range, 10 to 99 years) who underwent major vascularsurgery in our clinic were included. The NLR and PLRwere determined by dividing the absolute neutrophil andplatelet count by the absolute lymphocyte count.Results: The mean mortality risk was 2.85 (range 1.67-4.87) in patients with a NLR of ≥5 and 3.76 (range 2.31- 6.12) in patients with a PLR of ≥200. The proportion ofdiabetic patients was significantly higher for patients withNLR ≥5 (63.7%; p= 0.000) and PLR ≥200 (%53.8; p=0.003).Conclusion: Our study results showed that increased levelsof NLR and PLR were directly correlated with mortalityand inversely correlated with survival in the postoperativeperiod and that diabetic patients were under a higher risk.

Özet

Amaç: Bu çalışmada majör vasküler cerrahi yapılanhastalarda ameliyat öncesi nötrofil-lenfosit oranının(NLR) ve trombosit-lenfosit oranının (PLR) prognostik bir rolü olup olmadığı ve sağkalım ile olan ilişkisi araştırıldı. Ça­lış­ma pla­nı: Haziran 2005 ve Aralık 2012 tarihleri arasında majör vasküler cerrahi yapılan 838 ardışık hasta(593 erkek, 245 kadın; ort. yaş 63 yıl; dağılım 10-99 yıl) çalışmaya alındı. Mutlak nötrofil ve trombosit sayısının mutlak lenfosit sayısına bölünmesi ile NLR ve PLR hesaplandı. Bul­g u­l ar: Ortalama mortalite riski NLR ≥5 olan has-talarda 2.85 (dağılım 1.67-4.87), PLR ≥200 olan hasta-larda 3.76 (dağılım 2.31-6.12) idi. Diyabet hastalarınınoranı, NLR ≥5 (%63.7; p= 0.000) ve PLR ≥200 olanhastalarda (%53.8; p= 0.003) anlamlı düzeyde daha yüksekti. So­nuç: Çalışma bulgularımız artmış NLR ve PLR’ninameliyat sonrası mortalite ile doğrudan, sağkalım ile ters ilişkili olduğunu ve diyabetli hastaların daha yüksek riskaltında olduğunu gösterdi.

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Cite This Article

DEMİRAĞ, M. K., BEDİR, A. (2022). Majör vasküler cerrahi yapılan hastalarda ameliyat öncesi nötrofil-lenfosit oranı ve trombosit-lenfosit oranının değerlendirilmesi. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 21 - Sayı: 4, 930–935. https://ajindex.com/articles/424532

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