Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2016 / Cilt: 24 - Sayı: 2

Koroner arter baypas greft ameliyatı sonrasında atlanması kolay bir klinik olgu: Postoperatif deliryum

An easily overlooked clinical phenomenon after coronary artery bypass graft surgery: postoperative delirium

Pages
248–257
Publication Date
2022-09-02
DOI
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Mortality was observed in 10 patients (4.8%) in group 1 and three patients (0.4%) in group 2, suggesting that the difference was statistically significant (p=0.0001).Conclusion: Our study results show that complications can be minimized by analyzing the associated risk factors in the development of preoperative, perioperative, and postoperative delirium with a full collaboration with liaison psychiatry in the intensive care unit for the patients who are at risk for delirium.

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Objective & Hypothesis:Background: In this study, we aimed to investigate the prevalence of postoperative delirium in patients undergoing coronary artery bypass grafting and to identify possible risk factors associated with this complication.Methods: Between January 2009 and December 2013, data of a total of 935 patients (747 males, 188 females; mean age 64.3±8.4 years, range 32 to 86 years) who underwent coronary artery bypass grafting were retrospectively analyzed.
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Key Findings & Data:The patients were divided into two groups including group 1 patients (n=210) with early postoperative delirium and group 2 patients (n=725) attending to scheduled postoperative follow-up visits.Results: Delirium was significantly more common in the patients with demographic characteristics such as older age and male sex, history of alcohol intake, preoperative atrial fibrillation, increased creatinine levels, and chronic obstructive pulmonary disease (p<0.05).
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Conclusion & Impact:Mortality was observed in 10 patients (4.8%) in group 1 and three patients (0.4%) in group 2, suggesting that the difference was statistically significant (p=0.0001).Conclusion: Our study results show that complications can be minimized by analyzing the associated risk factors in the development of preoperative, perioperative, and postoperative delirium with a full collaboration with liaison psychiatry in the intensive care unit for the patients who are at risk for delirium.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: In this study, we aimed to investigate the prevalence of postoperative delirium in patients undergoing coronary artery bypass grafting and to identify possible risk factors associated with this complication.Methods: Between January 2009 and December 2013, data of a total of 935 patients (747 males, 188 females; mean age 64.3±8.4 years, range 32 to 86 years) who underwent coronary artery bypass grafting were retrospectively analyzed. The patients were divided into two groups including group 1 patients (n=210) with early postoperative delirium and group 2 patients (n=725) attending to scheduled postoperative follow-up visits.Results: Delirium was significantly more common in the patients with demographic characteristics such as older age and male sex, history of alcohol intake, preoperative atrial fibrillation, increased creatinine levels, and chronic obstructive pulmonary disease (p<0.05). The mean preoperative and postoperative platelet volume and C-reactive protein levels were higher in group 1 (p=0.0001). The mean aortic cross-clamp and cardiovascular bypass time, intubation time, Acute Physiology and Chronic Health Evaluation II score, and the length of stay in the intensive care unit and hospital were significantly higher in the patients with delirium (p<0.05). Sternum revision (p=0.0001) and new-onset atrial fibrillation (p=0.03) were significantly higher in group 1. Early neurological events were observed in 13 patients (6.2%) in group 1 and in 10 patients (1.4%) in group 2 (p=0.0001). Mortality was observed in 10 patients (4.8%) in group 1 and three patients (0.4%) in group 2, suggesting that the difference was statistically significant (p=0.0001).Conclusion: Our study results show that complications can be minimized by analyzing the associated risk factors in the development of preoperative, perioperative, and postoperative delirium with a full collaboration with liaison psychiatry in the intensive care unit for the patients who are at risk for delirium.

Özet

Amaç: Bu çalışmada koroner arter baypas greftleme yapılan hastalarda postoperatif deliryum prevalansı araştırıldı ve bu komplikasyon ile ilişkili muhtemel risk faktörleri belirlendi.Ça lış ma pla nı: Ocak 2009 - Aralık 2013 tarihleri arasında, koroner arter baypas greftleme yapılan toplam 935 hastanın (747 erkek, 188 kadın; ort. yaş 64.3±8.4 yıl; dağılım 32-86 yıl) verileri retrospektif olarak incelendi. Hastalar grup 1'de (n=201) erken evre postoperatif deliryumlu hastalar ve grup 2'de (n=725) ameliyat sonrası planlanan takip vizitlerine gelen hastalar olacak şekilde iki gruba ayrıldı.Bul gu lar: Deliryum, ileri yaş, erkek cinsiyeti, alkol kullanımı öyküsü, ameliyat öncesi atriyal fibrilasyon, kreatinin düzeylerinde artış ve kronik obstrüktif akciğer hastalığı gibi demografik özellikleri olan hastalarda anlamlı düzeyde daha sık görüldü (p<0.05). Ameliyat öncesi ve ameliyat sonrası ortalama trombosit hacmi ve C-reaktif protein düzeyleri, grup 1'de daha yüksekti (p=0.0001). Ortalama aortik kros klemp ve kardiyopulmoner baypas süresi, entübasyon süresi, Akut Fizyoloji ve Kronik Sağlık Değerlendirmesi II skoru, yoğun bakım ünitesi ve hastanede kalış süresi deliryumlu hastalarda anlamlı olarak daha yüksekti (p<0.05). Sternum revizyonu (p=0.0001) ve yeni başlangıçlı atriyal fibrilasyon (p=0.03) grup 1'de anlamlı düzeyde daha yüksekti. Erken dönem nörolojik olaylar grup 1'de 13 hastada (%6.2) ve grup 2'de 10 hastada (%1.4) görüldü (p=0.0001). Grup 1'de 10 hastada (%4.8) ve grup 2'de üç hastada (%0.4) mortalite gözlendi (p=0.0001); bu fark istatistiksel olarak anlamlı idi (p=0.0001).So nuç: Çalışma sonuçlarımız, deliryum riski taşıyan hastalar için yoğun bakım ünitesinde liyezon psikiyatrisi ile iş birliği içerisinde ameliyat öncesi, ameliyat sırası ve ameliyat sonrası deliryum gelişiminde ilişkili risk faktörleri analiz edilerek komplikasyonların en aza indirgenebileceğini göstermektedir.

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Cite This Article

ŞAŞKIN, H., DÜZYOL, Ç., AKSOY, R., İDİZ, M., MAÇİKA, H., ÖZCAN, K. S. (2022). Koroner arter baypas greft ameliyatı sonrasında atlanması kolay bir klinik olgu: Postoperatif deliryum. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 24 - Sayı: 2, 248–257. https://ajindex.com/articles/424099

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References (12)

  1. Wimmer-Greinecker G, Matheis G, Brieden M, Dietrich M, Oremek G, Westphal K, et al. Neuropsychological changes after cardiopulmonary bypass for coronary artery bypass grafting. Thorac Cardiovasc Surg 1998;46:207-12.
  2. McGuire BE, Basten CJ, Ryan CJ, Gallagher J. Intensive care unit syndrome: a dangerous misnomer. Arch Intern Med 2000;160:906-9.
  3. Yaşayacak A, Eker F. Determining delirium and risk factors of patients in cardiovascular surgery intensive care unit. Turk Gogus Kalp Dama 2012;20:265-74.
  4. Kazmierski J, Kowman M, Banach M, Fendler W, Okonski P, Banys A, et al. Incidence and predictors of delirium after cardiac surgery: Results from The IPDACS Study. J Psychosom Res 2010;69:179-85.
  5. Pandharipande P, Cotton BA, Shintani A, Thompson J, Pun BT, Morris JA Jr, et al. Prevalence and risk factors for development of delirium in surgical and trauma intensive care unit patients. J Trauma 2008;65:34-41.
  6. Ohki T, Matsushima E, Shibuya M, Sunamori M. An evaluation strategy for the early detection of postoperative delirium. Psychiatry Clin Neurosci 2006;60:277-82.
  7. Ely EW, Margolin R, Francis J, May L, Truman B, Dittus R, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med 2001;29:1370-9.
  8. Bucerius J, Gummert JF, Borger MA, Walther T, Doll N, Onnasch JF, et al. Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients. Ann Thorac Surg 2003;75:472-8.
  9. Eizadi-Mood N, Aghadavoudi O, Najarzadegan MR, Fard MM. Prevalence of delirium in opium users after coronary artery bypass graft surgery. Int J Prev Med 2014;5:900-6.
  10. Mu DL, Wang DX, Li LH, Shan GJ, Li J, Yu QJ, et al. High serum cortisol level is associated with increased risk of delirium after coronary artery bypass graft surgery: a prospective cohort study. Crit Care 2010;14:238. Eriksson M, Samuelsson E, Gustafson Y, Aberg T, Engström KG. Delirium after coronary bypass surgery evaluated by the organic brain syndrome protocol. Scand Cardiovasc J 2002;36:250-5.
  11. Zhang WY, Wu WL, Gu JJ, Sun Y, Ye XF, Qiu WJ, et al. Risk factors for postoperative delirium in patients after coronary artery bypass grafting: A prospective cohort study. J Crit Care 2015;30:606-12.
  12. Akıncı SB, Şahin A. Delirium in the intensive care unit. J Intensive Care 2005;5:26-35. American Psychiatric Association. Diagnostic and statistics manual of mental disorders. Arlington: American Psychiatric Publishing 2000. p. 135-80.