Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2016 / Cilt: 24 - Sayı: 4

Akut koroner sendromlu hastalarda atan kalpte komplet revaskülarizasyon deneyimimiz

Our experience with complete revascularization on beating heart in patients with acute coronary syndrome

Pages
666–671
Publication Date
2022-09-02
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The mean time to discharge was 8.4±3.8 (range, 3 to 27) days in the remaining patients.Conclusion: Our study results suggest that complete revascularization on a beating heart can be safely applied in the first-line setting in experienced centers for the surgical management of acute coronary syndrome, as it reduces systemic inflammatory response which may, otherwise, result from cardiopulmonary bypass, prevents global ischemia, and enables rapid reperfusion.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: In this study, we present our results with complete revascularization in patients with acute coronary syndrome undergoing coronary artery bypass grafting on beating heart.Methods: Between January 2014 and December 2014, a total of 48 patients (37 males; 11 females; mean age 62±10 years; range, 41 to 82 years) who underwent complete revascularization on beating heart with a diagnosis of acute coronary syndrome were retrospectively analyzed.
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Key Findings & Data:Postoperative intensive care unit parameters, 30-day mortality rate, and altered left ventricle systolic function were recorded.Results: The mean number of bypass graft anastomoses were 2.7±1.2 (range, 1 to 5) during a mean time of 49.2±2 (range, 10 to 122) min.
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Conclusion & Impact:The mean time to discharge was 8.4±3.8 (range, 3 to 27) days in the remaining patients.Conclusion: Our study results suggest that complete revascularization on a beating heart can be safely applied in the first-line setting in experienced centers for the surgical management of acute coronary syndrome, as it reduces systemic inflammatory response which may, otherwise, result from cardiopulmonary bypass, prevents global ischemia, and enables rapid reperfusion.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: In this study, we present our results with complete revascularization in patients with acute coronary syndrome undergoing coronary artery bypass grafting on beating heart.Methods: Between January 2014 and December 2014, a total of 48 patients (37 males; 11 females; mean age 62±10 years; range, 41 to 82 years) who underwent complete revascularization on beating heart with a diagnosis of acute coronary syndrome were retrospectively analyzed. Initial procedure consisted of the left internal thoracic artery-left anterior descending artery grafting in all patients. Following the revascularization of the left anterior descending artery, remaining anastomoses were performed. Postoperative intensive care unit parameters, 30-day mortality rate, and altered left ventricle systolic function were recorded.Results: The mean number of bypass graft anastomoses were 2.7±1.2 (range, 1 to 5) during a mean time of 49.2±2 (range, 10 to 122) min. The mean time from the onset of angina symptoms to surgery was 32.3±40 (range, 1 to 216) hours. One-third of the patients did not require any inotropic support postoperatively, while three patients required intraaortic balloon pump support. Two patients requiring intensive inotropic support and IABP during the immediate postoperative period died on postoperative Days 1 and 3, respectively. Another patient died due to complications associated with prolonged intensive care unit stay on postoperative Day 27. The mean time to discharge was 8.4±3.8 (range, 3 to 27) days in the remaining patients.Conclusion: Our study results suggest that complete revascularization on a beating heart can be safely applied in the first-line setting in experienced centers for the surgical management of acute coronary syndrome, as it reduces systemic inflammatory response which may, otherwise, result from cardiopulmonary bypass, prevents global ischemia, and enables rapid reperfusion.

Özet

Amaç: Bu çalışmada atan kalpte koroner arter baypas greftleme yapılan akut koroner sendromlu hastalarda komplet revaskülarizasyon sonuçlarımız bildirildi.Ça lış ma pla nı: Ocak 2014 - Aralık 2014 tarihleri arasında akut koroner sendrom tanısı ile atan kalpte komplet revaskülarizasyon uygulanan toplam 48 hasta (37 erkek, 11 kadın; ort. yaş: 62±10 yıl; dağılım, 41-82 yıl) retrospektif olarak incelendi. Başlangıç işlemi, tüm hastalarda sol internal torasik arter ve sol ön inen arter greftlemesi idi. Sol ön inen arterin revaskülarizasyonunu takiben, geriye kalan anastomozlar yapıldı. Ameliyat sonrası yoğun bakım parametreleri, 30 günlük mortalite oranları ve sol ventrikül sistolik fonksiyonundaki değişiklik kaydedildi.Bul gu lar: Ortalama baypas greft anastomoz sayısı, ortalama 49.2±2 dk. süresince 2.7 idi. Anjina semptomlarının başlamasından cerrahiye kadar geçen süre 32.3±40 saat idi. Hastaların üçte birinde ameliyat sonrası dönemde inotropik destek ihtiyacı olmazken, üç hastada intraaortik balon pompası desteği gerekti. Ameliyattan hemen sonraki dönemde yoğun inotropik destek ve intraaortik balon pompası gerekli olan iki hasta ameliyat sonrası sırasıyla 1. ve 3. günlerde kaybedildi. Bir diğer hasta da yoğun bakım ünitesinde uzun süreli kalışa bağlı komplikasyonlar nedeniyle ameliyat sonrası 27. günde kaybedildi. Diğer hastalarda taburculuğa kadar geçen ortalama süre, 8.4±3.8 gün idi.So nuç: Çalışma bulgularımız, aksi takdirde kardiyopulmoner baypas ile elde edilen sistemik inflamatuvar yanıtı azalttığı, global iskemiyi önlediği ve hızlı reperfüzyon sağladığı için, atan kalpte komplet revaskülarizasyonun akut koroner sendromun cerrahi tedavisinde deneyimli merkezlerde birinci basamakta güvenli bir şekilde uygulanabileceğini göstermektedir.

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Cite This Article

KAYA, E., IŞIK, Ö., FOTBOLCU, H., YAKUT, C. (2022). Akut koroner sendromlu hastalarda atan kalpte komplet revaskülarizasyon deneyimimiz. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 24 - Sayı: 4, 666–671. https://ajindex.com/articles/424064

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