Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2017 / Cilt: 25 - Sayı: 4

Inhaled nitric oxide induced methemoglobinemia on extracorporeal circulatory support: Black versus red

Ekstrakorporeal dolaşım desteğinde inhale nitrik oksidin indüklediği methemoglobinemi: Siyah kırmızıya karşı

Pages
644–646
Publication Date
2022-09-02
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Methemoglobinemia was successfully treated by exchange blood transfusion.

📌 3 Key Takeaways

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Objective & Hypothesis:Administration of inhaled nitric oxide after left ventricular assist device implantation decreases pulmonary vascular resistance and right ventricular afterload.
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Key Findings & Data:The methemoglobin levels up to 19.9% were accompanied by hypoxemia and fatal arrhythmias.
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Conclusion & Impact:Methemoglobinemia was successfully treated by exchange blood transfusion.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Administration of inhaled nitric oxide after left ventricular assist device implantation decreases pulmonary vascular resistance and right ventricular afterload. However, inhaled nitric oxide is not innocent and serious adverse effects may occur. In this article, we report a case of severe methemoglobinemia caused by inhaled nitric oxide administration after left ventricular assist device implantation. We stabilized the patient’s hemodynamic status with veno-arterial-venous extracorporeal membrane oxygenation support and inhaled nitric oxide treatment. Nevertheless, severe methemoglobinemia was detected with discolorization of the tubing lines of the extracorporeal membrane oxygenation circuit in association with hypoxia. The methemoglobin levels up to 19.9% were accompanied by hypoxemia and fatal arrhythmias. Methemoglobinemia was successfully treated by exchange blood transfusion.

Özet

Sol ventrikül destek cihazı yerleştirilmesi sonrası inhale nitrik oksit kullanılması pulmoner vasküler direnci ve sağ ventrikül ardyükünü azaltır. Ancak, inhale nitrik oksit masum değildir ve ciddi yan etkiler ortaya çıkabilir. Bu yazıda, sol ventrikül destek cihazı yerleştirilmesi sonrası inhale nitrik oksit uygulamasının neden olduğu ciddi bir methemoglobinemi olgusu bildirildi. Hastanın hemodinamik durumu veno-arteriyel-venöz ekstrakorporeal membran oksijenasyonu desteği ve inhale nitrik oksit tedavisi ile stabilize edildi. Yine de ekstrakorporeal membran oksijenasyonu boru hatlarında renk değişikliğinin hipoksiye eşlik ettiği ciddi methemoglobinemi belirlendi. Yüzde 19.9’a yükselen methemoglobin düzeylerine hipoksemi ve fatal aritmi eşlik etti. Methemoglobinemi kan transfüzyonu değişimi ile başarılı bir şekilde tedavi edildi.

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Cite This Article

ÖZÇINAR, E., AKAR, A. R., ERYILMAZ, S., GÜMÜŞ, F. (2022). Inhaled nitric oxide induced methemoglobinemia on extracorporeal circulatory support: Black versus red. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 25 - Sayı: 4, 644–646. https://ajindex.com/articles/423941

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References (5)

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