Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2019 / Cilt: 27 - Sayı: 4

Risk factors affecting post-traumatic acute respiratory distress syndrome development in thoracic trauma patients

Torasik travma hastalarında post-travmatik akut solunum sıkıntısı sendromu gelişimini etkileyen risk faktörleri

Pages
540–549
Publication Date
2022-09-02
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We defined a cutoff value for new injuryseverity score to predict post-traumatic acute respiratory distress syndrome

📌 3 Key Takeaways

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Objective & Hypothesis:Background: This study aims to investigate the risk factors affectingpost-traumatic acute respiratory distress syndrome development in thoracictrauma patients.Methods: This two-centered, retrospective study included 3,080 thoracictrauma patients (2,562 males, 518 females; mean age 33.9±19.4 years;range, 2 months to 91 years) treated between January 2005 and January2019.
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Key Findings & Data:Demographic characteristics, mechanisms of injury, traumaticinjuries, injury severity score and new injury severity score results,treatments, comorbidities, complications, morbidity and mortality rates,and durations of hospital stay were collected.
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Conclusion & Impact:We defined a cutoff value for new injuryseverity score to predict post-traumatic acute respiratory distress syndrome
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: This study aims to investigate the risk factors affectingpost-traumatic acute respiratory distress syndrome development in thoracictrauma patients.Methods: This two-centered, retrospective study included 3,080 thoracictrauma patients (2,562 males, 518 females; mean age 33.9±19.4 years;range, 2 months to 91 years) treated between January 2005 and January2019. Demographic characteristics, mechanisms of injury, traumaticinjuries, injury severity score and new injury severity score results,treatments, comorbidities, complications, morbidity and mortality rates,and durations of hospital stay were collected. Data were used to predictthe risk factors for development of post-traumatic acute respiratory distresssyndrome by univariate and multivariate statistical analysis.Results: Acute respiratory distress syndrome was detected in 81 patients.In multivariate logistic regression analysis; age, pulmonary contusion,intracranial hemorrhage, rib fracture (unilateral and four-five pieces),femur and tibia fracture, diabetes mellitus, chronic obstructive pulmonarydisease, blood transfusion (≥3 units), high white blood cell count atadmission, sepsis, and hepatic injury were detected as independent riskfactors (p<0.05). Optimal cutoff points (sensitivity/specificity ratios) foracute respiratory distress syndrome development risk were ≥16 (79%/68%)for injury severity score, ≥27 (90%/68.7%) for new injury severity score,and ≥16,000 (75.3%/71.6%) for admission white blood cell count. Newinjury severity score was superior than injury severity score to predict thedevelopment of acute respiratory distress syndrome.Conclusion: Acute respiratory distress syndrome causes significantmortality and morbidity in trauma patients. In addition to the well-knownrisk factors, diabetes mellitus and chronic obstructive pulmonary diseasewere independent risk factors. We defined a cutoff value for new injuryseverity score to predict post-traumatic acute respiratory distress syndrome

Özet

Amaç: Bu çalışmada torasik travma hastalarında post-travmatik akut solunum sıkıntısı sendromu gelişimini etkileyen risk faktörleri araştırıldı. Çalışma planı: Bu iki merkezli, retrospektif çalışmaya Ocak 2005-Ocak 2019 tarihleri arasında tedavi edilen 3,080 torasik travma hastası (2,562 erkek, 518 kadın; ort. yaş 33.9±19.4 yıl; dağılım, 2 ay-91 yıl) dahil edildi. Demografik özellikler, yaralanma mekanizmaları, travmatik yaralanmalar, yaralanma şiddeti skoru ve yeni yaralanma şiddeti skoru sonuçları, tedaviler, eşlik eden hastalıklar, komplikasyonlar, morbidite ve mortalite oranları ve hastane yatış süreleri toplandı. Veriler tek değişkenli ve çok değişkenli istatistiksel analiz yoluyla post-travmatik akut solunum sıkıntısı sendromu gelişimi için risk faktörlerini öngörmek üzere kullanıldı. Bulgular: Akut solunum sıkıntısı sendromu 81 hastada saptandı. Çok değişkenli lojistik regresyon analizinde yaş, pulmoner kontüzyon, kafa içi kanama, kaburga kırığı (tek taraflı ve dört-beş parça), femur ve tibia kırığı, diabetes mellitus, kronik obstrüktif akciğer hastalığı, kan transfüzyonu (≥3 ünite), başvuru anı yüksek beyaz küre sayımı, sepsis ve karaciğer yaralanması bağımsız risk faktörleri olarak saptandı (p<0.05). Akut solunum sıkıntısı sendromu gelişimi riski için optimal kestirim noktaları (duyarlılık/özgüllük oranları) yaralanma şiddeti skoru için ≥16 (%79/%68), yeni yaralanma şiddeti skoru için ≥27 (%90/%68.7) ve başvuru anı beyaz küre sayımı için ≥16000 (%75.3/%71.6) idi. Akut solunum sıkıntısı sendromu gelişimini öngörmede yeni yaralanma şiddeti skoru, yaralanma şiddeti skorundan daha üstün idi. Sonuç: Akut solunum sıkıntısı sendromu travma hastalarında ciddi mortalite ve morbiditeye neden olur. İyi bilinen risk faktörlerine ek olarak, diabetes mellitus ve kronik obstrüktif akciğer hastalığı bağımsız risk faktörleri idi. Post-travmatik akut solunum sıkıntısı sendromunu öngörmede yeni yaralanma şiddeti skoru için kestirim değeri tanımlandı

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Cite This Article

SARAÇ, E. Ö., AVCI, A., ONAT, S., ÖZÇELİK, C., EREN, T. Ş., ÜLKÜ, R. (2022). Risk factors affecting post-traumatic acute respiratory distress syndrome development in thoracic trauma patients. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 27 - Sayı: 4, 540–549. https://ajindex.com/articles/423796

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