Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2020 / Cilt: 28 - Sayı: 3

Lung transplantation for graft-versus-host disease after allogeneic stem cell transplantation: A report of two cases

Allojenik kök hücre transferi nakli greft-versus-host hastalığında akciğer nakli: İki olgu sunumu

Pages
543–546
Publication Date
2022-09-02
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Herein,we report two rare cases who underwent lung transplantationafter allogeneic stem cell transplantation.

📌 3 Key Takeaways

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Objective & Hypothesis:Allogeneic peripheral stem cell transplantation is an effectivetreatment of malignant and non-malignant hematologicaldiseases.
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Key Findings & Data:However, it is associated with several complications,such as graft-versus-host disease, and also various complicationsinvolving different organ systems.
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Conclusion & Impact:Herein,we report two rare cases who underwent lung transplantationafter allogeneic stem cell transplantation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Allogeneic peripheral stem cell transplantation is an effectivetreatment of malignant and non-malignant hematologicaldiseases. However, it is associated with several complications,such as graft-versus-host disease, and also various complicationsinvolving different organ systems. Late-onset non-infectiouslung complication is one of them. This pathology may also affectthe different anatomical regions in the lung as parenchymas,bronchi, or vessels and may manifest with different clinicalpresentations. Lung transplantation can be an effective treatmentin patients with pulmonary complications after allogeneic stemcell transplantation and also in patients who do not respond totreatment adequately and with a limited life expectancy. Herein,we report two rare cases who underwent lung transplantationafter allogeneic stem cell transplantation.

Özet

Malign olan ve olmayan hematolojik hastalıkların tedavisinde allojenik periferik kök hücre nakli etkili bir tedavidir. Ancak, greft-versus-host hastalığı gibi bazı komplikasyonlar ve çeşitli organ sistemlerini etkileyen komplikasyonlar ile ilişkilidir. Geç başlangıçlı non-enfeksiyöz akciğer komplikasyonu bunlardan biridir. Bu patoloji, akciğerlerin parankimler, bronşlar ve damarlar gibi anatomik bölgelerini de etkileyebilmekte ve farklı klinik tablolar ile kendini gösterebilmektedir. Akciğer nakli, allojenik kök hücre nakli sonrası pulmoner komplikasyon gelişen hastalarda ve aynı zamanda tedaviye yeterli düzeyde yanıt vermeyen ve yaşam beklentisi sınırlı olan hastalarda etkili bir tedavi yöntemi olabilir. Bu yazıda, allojenik kök hücre nakli sonrası akciğer nakli yapılan iki nadir olgu sunuldu.

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Cite This Article

VAYVADA, M., ERKILIÇ, A., ÖZTÜRK, E. B., TAŞÇI, A. E. (2022). Lung transplantation for graft-versus-host disease after allogeneic stem cell transplantation: A report of two cases. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 28 - Sayı: 3, 543–546. https://ajindex.com/articles/423708

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