Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2020 / Cilt: 28 - Sayı: 1

Atrial fibrillation after cardiac surgery and preoperative vitamin D levels: A systematic review and meta-analysis

Kalp cerrahisi sonrasında atriyal fibrilasyon ve ameliyat öncesi D vitamini düzeyleri: Sistematik derleme ve meta-analiz

Pages
101–107
Publication Date
2022-09-02
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

After thearticle titles and abstracts were analyzed, six articles involving769 patients which met the inclusion criteria were included.The results indicated that there was a relationship betweenpreoperative vitamin D levels and postoperative atrial fibrillation(SMD: -0.46, 95% CI: -0.79 to -0.12; p<0.007).

📌 3 Key Takeaways

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Objective & Hypothesis:Background: In this meta-analysis, we aimed to investigate thepossible relationship between atrial fibrillation development aftercardiac surgery and preoperative vitamin D levels.Methods: Literature review was carried out in the PubMed,ScienceDirect and Ovid electronic databases without any limitationof time frame.
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Key Findings & Data:The results of the studies wereevaluated based on either random or fixed effect model accordingto the presence of heterogeneity (I2>25%).Results: A total of 1,865 articles were screened.
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Conclusion & Impact:After thearticle titles and abstracts were analyzed, six articles involving769 patients which met the inclusion criteria were included.The results indicated that there was a relationship betweenpreoperative vitamin D levels and postoperative atrial fibrillation(SMD: -0.46, 95% CI: -0.79 to -0.12; p<0.007).
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: In this meta-analysis, we aimed to investigate thepossible relationship between atrial fibrillation development aftercardiac surgery and preoperative vitamin D levels.Methods: Literature review was carried out in the PubMed,ScienceDirect and Ovid electronic databases without any limitationof time frame. Published studies which recorded the preoperativelevels of vitamin D and atrial fibrillation after cardiac surgery inthe English language were included. The results of the studies wereevaluated based on either random or fixed effect model accordingto the presence of heterogeneity (I2>25%).Results: A total of 1,865 articles were screened. After thearticle titles and abstracts were analyzed, six articles involving769 patients which met the inclusion criteria were included.The results indicated that there was a relationship betweenpreoperative vitamin D levels and postoperative atrial fibrillation(SMD: -0.46, 95% CI: -0.79 to -0.12; p<0.007). Heterogeneitywas observed for studies conducted (I2 =76.1%).Conclusion: We concluded that low preoperative vitamin Dlevels were associated with the development of atrial fibrillationafter cardiac surgery. However, there is a need for large-scale,randomized-controlled trials for preventing the heterogeneity ofthe results.

Özet

Amaç: Bu meta-analizde, kalp cerrahisi sonrasında atriyal fibrilasyon gelişimi ve ameliyat öncesi D vitamini düzeyleri arasındaki muhtemel ilişki araştırıldı. Çalışma planı: Tarih sınırlaması olmaksızın PubMed, ScienceDirect ve Ovid elektronik veri tabanlarında literatür taraması yapıldı. Ameliyat öncesi D vitamini düzeylerinin ve ameliyat sonrası atriyal fibrilasyonun kaydedildiği İngilizce dilindeki yayımlanmış çalışmalar dahil edildi. Çalışma sonuçları, heterojenite varlığına göre rastgele etki veya sabit etki modeli ile değerlendirildi (I2>%25). Bulgular: Toplam 1865 makale tarandı. Makale başlıkları ve özetleri incelendikten sonra, dahil edilme kriterlerini karşılayan 769 hastayı kapsayan altı makale alındı. Bulgular, D vitamini düzeyleri ile ameliyat sonrası atriyal fibrilasyon arasında bir ilişki olduğunu gösterdi (SMD: -0.46, %95 CI: -0.79 ila - 0,12; p<0.007). Yürütülen çalışmalarda heterojenite gözlendi (I2 =%76.1). Sonuç: Ameliyat öncesi düşük D vitamini düzeylerinin kalp cerrahisinden sonra atriyal fibrilasyon gelişimi ile ilişkili olduğu sonucuna varıldı. Ancak bulgulardaki heterojeniteyi önlemek için daha geniş ölçekli, randomize kontrollü çalışmalara ihtiyaç vardır.

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Cite This Article

ÖZTÜRK, S., ÖZTÜRK, İ. (2022). Atrial fibrillation after cardiac surgery and preoperative vitamin D levels: A systematic review and meta-analysis. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 28 - Sayı: 1, 101–107. https://ajindex.com/articles/423653

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