Journals / Türk Göğüs Kalp Damar Cerrahisi Dergisi / 2021 / Cilt: 29 - Sayı: 2

Anesthetic management in lung transplantation: Our single-center experience

Akciğer naklinde anestezi yönetimi: Tek merkez deneyimimiz

Pages
191–200
Publication Date
2022-09-02
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A close communication should be maintained between the surgeons, perfusion technicians, and anesthesiologists to ensure an optimal multidisciplinary approach and to achieve successful outcomes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: In this study, we aimed to discuss our anesthesia management strategies, experiences, and outcomes in patients undergoing lung transplantation.
📊
Key Findings & Data:Methods: Between December 2016 and December 2018, a total of 53 patients (43 males, 10 females; mean age: 46.1±13 years; range, 14 to 64 years) undergoing lung transplantation in our center were included.
💡
Conclusion & Impact:A close communication should be maintained between the surgeons, perfusion technicians, and anesthesiologists to ensure an optimal multidisciplinary approach and to achieve successful outcomes.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Background: In this study, we aimed to discuss our anesthesia management strategies, experiences, and outcomes in patients undergoing lung transplantation. Methods: Between December 2016 and December 2018, a total of 53 patients (43 males, 10 females; mean age: 46.1±13 years; range, 14 to 64 years) undergoing lung transplantation in our center were included. The anesthesia technique, patients’ characteristics, and perioperative clinical and follow-up data were recorded. The stage of lung disease was assessed using the New York Heart Association functional classification. Results: Two patients underwent single lung transplantation, while 51 patients underwent double lung transplantation. Idiopathic pulmonary fibrosis was the most common indication in 41.5% of the patients. All patients had end-stage lung disease (Class IV) and 79% were oxygen-dependent. The extracorporeal membrane oxygenation support was given to 32 patients. Conclusion: The anesthetic management of lung transplantation is challenging, either due to the deterioration of the recipient’s physical performance and the complexity of the surgical techniques used. In general, a kind of mechanical support may be needed and extracorporeal membrane oxygenation is the first choice in the majority of patients. A close communication should be maintained between the surgeons, perfusion technicians, and anesthesiologists to ensure an optimal multidisciplinary approach and to achieve successful outcomes.

Özet

yönetim stratejilerimiz, deneyimlerimiz ve sonuçlarımız tartışıldı. Çalışma planı: Aralık 2016 - Aralık 2018 tarihleri arasında, merkezimizde akciğer nakli yapılan toplam 53 hasta (43 erkek, 10 kadın; ort. yaş: 46.1±13 yıl; dağılım, 14-64 yıl) çalışmaya alındı. Kullanılan anestezi tekniği, hastaların özellikleri ve perioperatif klinik ve takip verileri kaydedildi. Akciğer hastalığının evresi, New York Kalp Derneği fonksiyonel sınıflamasına göre değerlendirildi. Bulgular: İki hastaya tek taraflı akciğer nakli ve 51 hastaya çift taraflı akciğer nakli yapıldı. İdiyopatik pulmoner fibroz, hastaların %41.5’inde en sık endikasyon idi. Hastaların tümünde son dönem akciğer hastalığı (Sınıf IV) mevcut idi ve %79’u oksijene bağımlı idi. Otuz iki hastaya ekstrakorporeal membran oksijenasyon desteği verildi. Sonuç: Akciğer naklinde anestezi yöntemi, gerek alıcının fiziksel performansının kötüleşmesi, gerekse kullanılan cerrahi tekniklerin karmaşık yapısı nedeniyle zordur. Genel olarak, bir çeşit mekanik destek gerekebilir ve hastaların birçoğunda ekstrakorporeal membran oksijenasyonu ilk tercihtir. İdeal bir multidisipliner yaklaşım sağlamak ve başarılı sonuçlar elde etmek için cerrahlar, perfüzyonistler ve anesteziyolojistlerin arasında iyi bir iletişim kurulmalıdır.

🔖

Cite This Article

ERKILINÇ, A., GÜRCÜ, M. E., BAYSAL, P. K. (2022). Anesthetic management in lung transplantation: Our single-center experience. Türk Göğüs Kalp Damar Cerrahisi Dergisi, Cilt: 29 - Sayı: 2, 191–200. https://ajindex.com/articles/423590

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Myles PS, Weeks AM, Buckland MR, Silvers A, Bujor M, Langley M. Anesthesia for bilateral sequential lung transplantation: Experience of 64 cases. J Cardiothorac Vasc Anesth 1997;11:177-83
  2. Slinger P. Anaesthetic management for lung transplantation. Tx Med 2012;24:27-34
  3. Hardy JD, Webb WR, Dalton ML Jr, Walker GR Jr. LUNG Homotransplantation in man. JAMA 1963;186:1065-74
  4. Trulock EP, Christie JD, Edwards LB, Boucek MM, Aurora P, Taylor DO, et al. Registry of the International Society for Heart and Lung Transplantation: Twenty-fourth official adult lung and heart-lung transplantation report-2007. J Heart Lung Transplant 2007;26:782-95
  5. Liu N, Chazot T, Trillat B, Michel-Cherqui M, Marandon JY, Law-Koune JD, et al. Closed-loop control of consciousness during lung transplantation: An observational study. J Cardiothorac Vasc Anesth 2008;22:611-5
  6. Tomasi R, Betz D, Schlager S, Kammerer T, Hoechter DJ, Weig T, et al. Intraoperative anesthetic management of lung transplantation: Center-specific practices and geographic and centers size differences. J Cardiothorac Vasc Anesth 2018;32:62-9
  7. Miranda A, Zink R, McSweeney M. Anesthesia for lung transplantation. Semin Cardiothorac Vasc Anesth 2005;9:205-12
  8. Alvarez-Ayuso L, Calero P, Granado F, Jorge E, Herrero C, Torralba A, et al. Antioxidant effect of gamma-tocopherol supplied by propofol preparations (Diprivan) during ischemia-reperfusion in experimental lung transplantation. Transpl Int 2004;17:71-7
  9. Edward GM, Maged Jr S, Mikhail MN. Non-volatil anestezik ajanlar. Çeviri editörleri: Tulunay M, Cuhruk H. Klinik anesteziyoloji
  10. Baskı. Ankara: Güneş Tıp Kitapevleri; 2008. s. 179-205
  11. Chai J, Long B, Liu X, Li Y, Han N, Zhao P, et al. Effects of sevoflurane on tight junction protein expression and PKC-α translocation after pulmonary ischemia-reperfusion injury. Exp Mol Med 2015;47:e167
  12. Casanova J, Garutti I, Simon C, Giraldez A, Martin B, Gonzalez G, et al. The effects of anesthetic preconditioning with sevoflurane in an experimental lung autotransplant model in pigs. Anesth Analg 2011;113:742-8
  13. Russell WJ. A logical approach to the selection and insertion of double-lumen tubes. Curr Opin Anaesthesiol 2008;21:37-40
  14. Brodsky JB, Lemmens HJ. Left double-lumen tubes: Clinical experience with 1,170 patients. J Cardiothorac Vasc Anesth 2003;17:289-98
  15. Della Rocca G, Brondani A, Costa MG. Intraoperative hemodynamic monitoring during organ transplantation: What is new? Curr