Journals / Ağrı / 2019 / Cilt: 31 - Sayı: 2

The short-term effect of PRP on chronic pain in knee osteoarthritis

Diz osteoartritinde PRP’nin kronik ağrı üzerine kısa dönem etkinliği

Journal
Ağrı
Pages
63–69
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Asignificant improvement was observed in the mean resting and activity VAS scores at day 0 and week 12 (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The administration of platelet-rich plasma (PRP), which increases the release of growth factors targeting cartilageregeneration, is used in an effort to relieve pain in knee osteoarthritis (OA).
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Key Findings & Data:This study measured the short-term efficacy of PRPon chronic pain in patients with OA of the knee.Methods: Patients with chronic knee pain and grade 2-4 knee OA based on the Kellgren-Lawrence (K-L) classification were enrolledin the study.
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Conclusion & Impact:Asignificant improvement was observed in the mean resting and activity VAS scores at day 0 and week 12 (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: The administration of platelet-rich plasma (PRP), which increases the release of growth factors targeting cartilageregeneration, is used in an effort to relieve pain in knee osteoarthritis (OA). This study measured the short-term efficacy of PRPon chronic pain in patients with OA of the knee.Methods: Patients with chronic knee pain and grade 2-4 knee OA based on the Kellgren-Lawrence (K-L) classification were enrolledin the study. A total of 60 knee joints of 42 patients who completed 3 doses of intraarticular PRP injections administeredat intervals of 3 weeks were analyzed. The patients’ pain was evaluated using a resting and activity visual analog scale (VAS)on day 0, and at week 3, 6, and 12.Results: Of the 42 patients, 37 were female. The mean age and body mass index was 60.52±10.41 years and 28.5±9.71 kg/m2. A total of 18 patients had bilateral knee involvement, and 39 of the 60 knee joints were classified as K-L grade 3-4 OA. Asignificant improvement was observed in the mean resting and activity VAS scores at day 0 and week 12 (p

Özet

Amaç: Diz osteoartritinde (OA) kıkırdak rejenerasyonu sağlamaya yönelik büyüme faktörlerinin salınımını artıran platelet rich plasma (PRP) uygulamaları ile diz ağrılarında iyileşme sağlanmaya çalışılmaktadır. Biz de bu nedenle diz OA’da PRP’nin kronik ağrı üzerine kısa dönem etkinliğini ölçmeyi amaçladık. Gereç ve Yöntem: Kellgren – Lawrence (K-L) sınıflamasına göre grade 2-4 arası diz OA olan kronik diz ağrılı 69 hasta çalışmaya alındı. 3 hafta aralıklarla uygulanan 3 doz intraartiküler PRP enjeksiyonunu tamamlayan 42 hastanın 60 diz eklemi ile çalışma tamamlandı. Hastaların ağrıları 0. gün, 3., 6., ve 12. haftalarda istirahat ve aktivite visual analog scala (VAS) ile değerlendirildi. Bulgular: 37’si kadın 42 hastanın ortalama yaşı ve vücut kitle indeksi sırasıyla (ort±standart sapma (SS)) 60.52±10.41 ve 28.5±9.71 idi. Toplam 18 hasta bilateral diz olup, 60 diz ekleminin 39’u ise K-L grade 3-4 osteoartritti. Hastaların 0. gün ve 12. hafta ortalama istirahat ve aktivite VAS skorlarında; (sırasıyla (ort±SS), 5.13±2.70, 7.68±1.83 ve 2.60±2.05, 3.75±2.12, p

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Cite This Article

SUCUOĞLU, H., ÜSTÜNSOY, S. (2022). The short-term effect of PRP on chronic pain in knee osteoarthritis. Ağrı, Cilt: 31 - Sayı: 2, 63–69. https://ajindex.com/articles/421777

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