Journals / Cukurova Medical Journal / 2021 / Cilt: 46 - Sayı: 3

Evaluation of hysteroscopy findings in infertility patients with IVF-ICSI / ET failure

IVF-ICSI/ET başarısızlığı olan infertil hastalarda histeroskopi bulgularının değerlendirilmesi

Pages
1168–1174
Publication Date
2021-09-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thus, it can contribute positively to the management of patients with IVF failure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: The aim of this study was to determine intrauterine pathologies by hysteroscopy in patients who have undergone IVF-ICSI/ET (in vitro fertilization intracytoplasmic sperm injection / embryo transfer) and have failed, and to classify and evaluate these pathologies.
📊
Key Findings & Data:Materials and Methods: This retrospective study was conducted between 2013 and 2019 at the Reproductive Endocrinology and Infertility Department of Çukurova University Faculty of Medicine, Balcalı Hospital.
💡
Conclusion & Impact:Thus, it can contribute positively to the management of patients with IVF failure.
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:İnfertilite · IVF-ICSI/ET · histereskopi

Abstract

Purpose: The aim of this study was to determine intrauterine pathologies by hysteroscopy in patients who have undergone IVF-ICSI/ET (in vitro fertilization intracytoplasmic sperm injection / embryo transfer) and have failed, and to classify and evaluate these pathologies. Materials and Methods: This retrospective study was conducted between 2013 and 2019 at the Reproductive Endocrinology and Infertility Department of Çukurova University Faculty of Medicine, Balcalı Hospital. In this study, patients with primary or secondary infertility diagnosis who applied to the infertility outpatient clinic, who had previously undergone IVF-ICSI / ET and failed and therefore underwent hysteroscopy were included. Results: The hysteroscopy results of 228 patients included in the study were evaluated. Of these, 42.5% (n = 97) had normal hysteroscopic findings, 57.5% (n = 131) had abnormal hysteroscopic findings. When these abnormal findings were examined, the most common pathology was endometrial polyp 23.1% (n=36). Other findings were; intrauterine synechiae 20.5% (n =32), cervical pathology 18.6% (n =29), cervical stenosis 13.5% (n =21), uterine subseptum 10.9% (n =17), myoma uteri 4.5% (n =7), arcuate uterus 3.2% (n =5), T-shaped uterus 3.2% (n =5), intrauterine infection 1.9% (n =3), and vaginal septum 0.6% (n =1). Conclusion: Additional investigations for the cause should be performed in patients with implantation failure. The positive effect of hysteroscopy on IVF is related to its detection and treatment of lesions in the endometrial cavity. In addition, hysteroscopy can detect intrauterine pathologies missed by other research methods. Thus, it can contribute positively to the management of patients with IVF failure.

Özet

fertilizasyon-intrastoplazmik sperm injeksiyonu/embriyo transferi) yapılmış ve başarısız olunmuş hastalarda histeroskopi ile intrauterin patolojileri saptamak ve bu patolojileri sınıflandırıp değerlendirilmesidir. Gereç ve Yöntem: Bu retrospektif çalışma 2013-2019 yılları arasında Çukurova Üniversitesi Tıp Fakültesi Balcalı Hastanesi Üreme Endokrinolojisi ve İnfertilite Bölümü’nde yapılmıştır. Bu çalışmaya, infertilite polikliniği’ne başvuran primer veya sekonder infertilite tanılı, daha önceden IVF-ICSI/ET yapılıp başarısızlıkla sonuçlanan ve bu nedenle histeroskopi uygulanan hastalar dahil edilmiştir. Bulgular: Çalışmaya alınan 228 hastanın histeroskopi sonuçları değerlendirildi. Bunlardan, %42,5’i (n=97) normal histeroskopik bulgulara, %57,5’i (n=131) anormal histeroskopik bulgulara sahipti. Bu anormal bulgular incelendiğinde, en sık izlenen patoloji endometrial polip %23,1 (n=36) idi. Diğer bulgular; intrauterin sineşi %20,5 (n=32), servikal patoloji %18,6 (n=29), servikal stenoz %13,5 (n=21), uterin subseptum %10,9 (n=17), myoma uteri %4,5 (n=7), arkuat uterus %3,2 (n=5), T-shape uterus %3,2 (n=5), intrauterin enfeksiyon %1,9 (n=3) ve vajinal septum %0,6 (n=1) idi. Sonuç: İmplantasyon başarısızlığı olan hastalarda nedene yönelik ek incelemeler yapılmalıdır. Histeroskopinin IVF üzerine olan pozitif etkisi endometrial kavitedeki lezyonları saptama ve tedavi etmesi ile ilişkilidir. Ayrıca histeroskopi, diğer araştırma yöntemleri tarafından gözden kaçırılan intrauterin patolojileri saptayabilir. Böylece IVF başarısızlığı olan hastaların yönetimine olumlu katkı sağlayabilir.

🔖

Cite This Article

TÜREYİCİ, L., KAHVECİ, B., ÜRÜNSAK, İ. F. (2021). Evaluation of hysteroscopy findings in infertility patients with IVF-ICSI / ET failure. Cukurova Medical Journal, Cilt: 46 - Sayı: 3, 1168–1174. https://ajindex.com/articles/420809

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Workup I, Specialist H. Infertility Workup for the Women’s Health Specialist: ACOG Committee Opinion, Number 781. Obstet Gynecol. 2019;133:377-84
  2. Coughlan C, Ledger W, Wang Q, Liu F, Demirol A, Gurgan T et al. Recurrent implantation failure: definition and management. Reprod Biomed Online. 2014;28:14-38
  3. Bashiri A, Halper KI, Orvieto R. Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions. Reprod Biol Endocrinol. 2018;16:1-18
  4. Orvieto R, Brengauz M, Feldman B. A novel approach to normal responder patient with repeated implantation failures--a case report. Gynecol Endocrinol. 2015;31:435-7
  5. Zeyneloglu HB, Onalan G. Remedies for recurrent implantation failure. Semin Reprod Med. 2014;32:297-305
  6. Gardner DK, Weissman A, Howles CM and Shoham Z. Text-book of Assisted Reproductive Techniques Volume:2 Clinical Perspectives, Fifth edition, Recurren implantation failure. 2018. Part 51:662-73
  7. Mascarenhas MN, Flaxman SR, Boerma T, Vanderpoel S, Stevens GA. National, Regional, and Global Trends in Infertility Prevalence Since 1990: A Systematic Analysis of 277 Health Surveys. PLoS Med. 2012;9:e1001356
  8. Zegers-Hochschild F, Adamson GD, Dyer S, Racowsky C, De Mouzon J, Sokol R, et al. The International Glossary on Infertility and Fertility Care. Fertil Steril. 2017;108:393-406
  9. Speroff L, Glass NH. Clinical Gynecologic Endocrinology and Infertility. 7nd edition. Wolter Kluvwer/Lippincot Williams& Wilkinswer/Lippincot Williams& Wilkins, 2007:84-116
  10. Hoffman B, Schorge JO, Schaffer JI, Halvorson LM, Bradshaw K, Cunningham FG. Williams jinekoloji. Çev. Ed. Yıldırım G. İstanbul: Nobel Tıp Kitabevleri. 2015
  11. Moustafa S, Young SL. Diagnostic and therapeutic options in recurrent implantation failure. F1000Res. 2020;25:F1000 Faculty Rev-208
  12. Ovarian Stimulation TEGGO, Bosch E, Broer S, Griesinger G, Grynberg M, Humaidan P, et al. ESHRE guideline: ovarian stimulation for IVF/ICSI†. Hum Reprod Open. 2020;2020:hoaa009
  13. Moini A, Kiani K, Ghaffari F, Hosseini F. Hysteroscopic findings in patients with a history of two implantation failures following in vitro fertilization. Int J Fertil Steril. 2012;6: 27-30
  14. Kirsop R, Porter R, Torode H, Smith D, Saunders D. The Role of Hysteroscopy in Patients Having Failed IVF/GIFT Transfer Cycles. Aust New Zeal J Obstet Gynaecol. 1991;31:263-4
  15. Valle RF. Hysteroscopy in the evaluation of female infertility. Am J Obstet Gynecol. 1980;137:425-31.