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Journals / Düzce Tıp Fakültesi Dergisi / 2014 / Cilt: 16 - Sayı: 3

A Case of Dapsone Overdose Induced Methemoglobinemia

YÜKSEK DOZ DAPSON ALIMINA BAĞLI METHEMOGLOBİNEMİ OLGUSU

İsa BAŞPINAR
Mehmet Akif KARAMERCAN
Figen COŞKUN
Yavuz KATIRCI
Pages
40–41
Publication Date
2014-12-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here in wepresent a case of methemoglobinemia due to intentional ingestion of 4 gr dapson

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Dapsone is a drug with potent anti-inflammatory and anti-parasitic activities, which waspreviously used almost exclusively for the treatment of leprosy.
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Key Findings & Data:Dapson rarely induce oxidationof haemoglobin which overwhelms the activity of intrinsic red cell methaemoglobin reductaseresulting in significant methaemoglobinaemia.
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Conclusion & Impact:Here in wepresent a case of methemoglobinemia due to intentional ingestion of 4 gr dapson
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Dapson · methemoglobinemi · acil tıp

Abstract

Dapsone is a drug with potent anti-inflammatory and anti-parasitic activities, which waspreviously used almost exclusively for the treatment of leprosy. Dapson rarely induce oxidationof haemoglobin which overwhelms the activity of intrinsic red cell methaemoglobin reductaseresulting in significant methaemoglobinaemia. Methylene blue and hemodialysis are consideredas treatment options of metheamoglobinemia together with supportive treatment. Here in wepresent a case of methemoglobinemia due to intentional ingestion of 4 gr dapson

Özet

Dapson potent antiinflamatuar ve antiparazitik etkileri olan Lepra tedavisi için kullanılan birilaçtır. Nadiren eritrosit içerisinde yer alan hemoglobin redüktaz enzimini inhibe ederek,hemoglobinin oksidasyonunu azaltır. Tedavide metilen mavisi ve hemodiyaliz ve destektedavileri uygulanır. Bu calismamizda, kasıtlı olarak 4 gr Dapson alımına bağlı olusan birmethemoglobinemi tablosunu sunmayı amaçladık

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Cite This Article

BAŞPINAR, İ., KARAMERCAN, M. A., COŞKUN, F., KATIRCI, Y. (2014). A Case of Dapsone Overdose Induced Methemoglobinemia. Düzce Tıp Fakültesi Dergisi, Cilt: 16 - Sayı: 3, 40–41. https://ajindex.com/articles/420554

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References (5)

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