The results obtained from this study showed that G. mellonella can be used as a model organism in the evaluation of the physiological effects of K. oxytoca infection on the host.
📌 3 Key Takeaways
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Objective & Hypothesis:In this study, the physiological and biochemical response of model insect Galleria mellonella due to Klebsiella oxytoca infection was investigated.
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Key Findings & Data:Changes in metabolic enzyme activities such as aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), amylase (AMYL) and gamma glutamyl transferase (GGT) occurred due to K. oxytoca infection.
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Conclusion & Impact:The results obtained from this study showed that G. mellonella can be used as a model organism in the evaluation of the physiological effects of K. oxytoca infection on the host.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
In this study, the physiological and biochemical response of model insect Galleria mellonella due to Klebsiella oxytoca infection was investigated. Changes in metabolic enzyme activities such as aspartate transferase (AST), alanine transferase (ALT), alkaline phosphatase (ALP), amylase (AMYL) and gamma glutamyl transferase (GGT) occurred due to K. oxytoca infection. In addition, amounts of non-enzymatic antioxidant such as uric acid (UA), bilirubin (BIL) and albumin (ALB) were altered in G. mellonella hemolymph due to infection. The results obtained from this study showed that G. mellonella can be used as a model organism in the evaluation of the physiological effects of K. oxytoca infection on the host.
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Cite This Article
SUGEÇTİ, S., ÇELİK, C., BÜYÜKGÜZEL, E., BÜYÜKGÜZEL, K. (2021). Physiological and Biochemical Effects of Klebsiella oxytoca Infection on Model Organism Galleria mellonella L.. Journal of the Entomological Research Society, Cilt: 23 - Sayı: 3, 279–286. https://ajindex.com/articles/418592
Alp, E. & Coskun, M. (2018). Effects of the organophosphate insecticide fenthion on the antioxidant defense system and lipid peroxidation of Galleria mellonella L. Fresenius Environmental Bulletin 27, 8280-8285.
Altuntaş, H. & Duman, E. (2017). Toxicological effects of the entomopathogenic Purpureocillium lilacinus on the model organism, Galleria mellonella. Biological Diversity and Conservation, 10(1), 153-159.
Andrejko, M., Zdybicka-Barabas, A., & Cytryńska, M. (2014). Diverse effects of Galleria mellonella infection with entomopathogenic and clinical strains of Pseudomonas aeruginosa. Journal of Invertebrate Pathology, 115, 14-25.
Bassetti, M., Giacobbe D.R., Giamarellou, H., Viscoli, C., Daikos, G.L., Dimopoulos, G., & Karaiskos, I. (2018). Management of KPC-producing Klebsiella pneumoniae infections. Clinical Microbiology and Infection, 24, 133-144.
Bronskill, J. (1961). A cage to simplify the rearing of the greater wax moth, Galleria mellonella (Pyralidae), Journal of the Lepidopterists’ Society, 15, 102-104.
Çelik, C., Büyükgüzel, K., & Büyükgüzel, E. (2019). The effects of oxyclozanide on survival, development and total protein of Galleria mellonella L. (Lepidoptera: Pyralidae), Journal of the Entomological Research Society, 21, 95-108.
Çelik, E. & Sak, O. (2020). Effects of kinetin on biological parameters and hemocytes of Achroia grisella (Lepidoptera: Pyralidae). Archives of Biological Sciences, 72, 181-192.
Dubovskii, I. M., Olifirenko, O. A., & Glupov, V. V. (2005). Level and activities of antioxidants in intestine of larvae Galleria mellonella L. (Lepidoptera, Pyralidae) at peroral infestation by bacteria Bacillus thuringiensis ssp. galleriae. Journal of Evolutionary Biochemistry and Physiology, 41, 20-25.
Dubovskii, I.M., Grizanova, E.V., Chertkova, E.A., Slepneva, I.A., Komarov, D.A., Vorontsova, Y.L., & Glupov, V.V. (2010). Generation of reactive oxygen species and activity of antioxidants in hemolymph of the moth larvae Galleria mellonella (L.) (Lepidoptera: Piralidae) at development of the process of encapsulation. Journal of Evolutionary Biochemistry and Physiology, 46, 35-43.
Etebari, K., Bizhannia, A.R., Sorati, R., & Matindoost, L. (2007). Biochemical changes in haemolymph of silkworm larvae due to pyriproxyfen residue. Pesticide Biochemistry and Physiology, 88, 14-19.
Farahani, S., Bandani, A.R., Alizadeh, H., Goldansaz, S.H., & Whyard, S. (2020). Differential expression of heat shock proteins and antioxidant enzymes in response to