Journals / Turkish Thoracic Journal / 2020 / Cilt: 21 - Sayı: 3

Evaluation of Subclinical Atherosclerosis with Carotid Intima-Media and Epicardial Fat Thickness in Patients with Sarcoidosis

Pages
174–179
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

These results indicate thatthe risk of subclinical atherosclerosis might be increased in these patients.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVES: Since many similar mechanisms may play a role in the pathophysiology of sarcoidosis and atherosclerosis, the risk of subclinical atherosclerosis may be increased in patients with sarcoidosis.
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Key Findings & Data:The aim of this study was to evaluate known markers of subclinicalatherosclerosis, namely epicardial fat thickness (EFT) and carotid intima-media thickness (CIMT) in patients with sarcoidosis.MATERIALS AND METHODS: This cross-sectional study included a total of 183 subjects, including 94 patients with sarcoidosis (patientgroup) and a control group of 89 healthy individuals.
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Conclusion & Impact:These results indicate thatthe risk of subclinical atherosclerosis might be increased in these patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

OBJECTIVES: Since many similar mechanisms may play a role in the pathophysiology of sarcoidosis and atherosclerosis, the risk of subclinical atherosclerosis may be increased in patients with sarcoidosis. The aim of this study was to evaluate known markers of subclinicalatherosclerosis, namely epicardial fat thickness (EFT) and carotid intima-media thickness (CIMT) in patients with sarcoidosis.MATERIALS AND METHODS: This cross-sectional study included a total of 183 subjects, including 94 patients with sarcoidosis (patientgroup) and a control group of 89 healthy individuals. Measurements of EFT and CIMT were taken from all subjects and recorded. Thegroups were compared, and differences were analyzed statistically.RESULTS: EFT was higher in patients than in control subjects (6.42±1.12 mm vs 7.13±1.41 mm, p<0.001). CIMT was higher in patientsthan in control subjects (0.51±0.02 mm vs 0.52±0.02 mm, p=0.003).CONCLUSION: EFT and CIMT were found to be higher in patients with sarcoidosis than in healthy people. These results indicate thatthe risk of subclinical atherosclerosis might be increased in these patients.

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Cite This Article

YILMAZ, H. E. B., YILMAZ, M., EROL, T., ŞEN, N., ÜNSAL, Z. E., KARA, S., HABEŞOĞLU, M. A., AKÇAY, Ş. (2020). Evaluation of Subclinical Atherosclerosis with Carotid Intima-Media and Epicardial Fat Thickness in Patients with Sarcoidosis. Turkish Thoracic Journal, Cilt: 21 - Sayı: 3, 174–179. https://ajindex.com/articles/417967

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References (12)

  1. Ramachandraiah V, Aronow W, Chandy D. Pulmonary sarcoidosis: an update. Postgrad Med 2017
  2. [Crossref] 2. Nowiński A, Puścińska E, Goljan A et al. The influence of comorbidities on mortality in sarcoidosis: a observational prospective cohort study. Clin Respir J 2018
  3. [Crossref] 3. Ungprasert P, Crowson CS, Matteson EL. Smoking, obesity and risk of sarcoidosis: A population-based nested case-control study. Respir Med 2016
  4. [Crossref] 4. Benjamin EJ, Blaha MJ, Chiuve SE, et al. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2017 update: A report from the American Heart Association. Circulation. 2017
  5. e146- e603. [Crossref] 5. Piepoli MF, Hoes AW, Agewall S, et al. Authors/Task Force Members. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts)Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 2016
  6. [Crossref] 6. Synetos A, Papaioannou S, Tousoulis D. Atherosclerosis and inflammation. Clinical aspects of a modern tale. Hellenic J Cardiol 2017
  7. [Crossref] 7. Kattoor AJ, Pothineni NVK, Palagiri D, et al. Oxidative stress in Atherosclerosis. Curr Atheroscler Rep 2017
  8. [Crossref] 8. Nerlekar N, Brown AJ, Muthalaly RG, et al. Association of Epicardial Adipose Tissue and High-Risk Plaque Characteristics: A Systematic Review and Meta-Analysis. J Am Heart Assoc 2017
  9. 6pii:e006379. [Crossref] 9. Carpenter M, Sinclair H, Kunadian V. Carotid intima media thickness and its utility as a predictor of cardiovascular disease: a review of evidence. Cardiol Rev 2016
  10. [Crossref] 10. Naqvi TZ, Lee MS. Carotid intima-media thickness and plaque in cardiovascular risk assessment. JACC Cardiovasc Imaging 2014
  11. [Crossref] 11. Altin C, Sade LE, Gezmis E, et al. Assessment of epicardial adipose tissue and carotid/femoral intima media thickness in insulin resistance. J Cardiol 2017
  12. [Crossref] 12. American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias, This joint statement of the American Thoracic Society