Journals / Turkish Neurosurgery / 2013 / Cilt: 23 - Sayı: 6

Elektromanyetik dalgaların Sıçan Beyin dokusu Üzerine Etkileri: deneysel Çalışma

The Effect of Electromagnetic Radiation on the Rat Brain: An Experimental Study

Pages
707–715
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This deterioration can cause to disease including loss of these areas function and cancer development.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: The aim of this study is to determine the structural changes of electromagnetic waves in the frontal cortex, brain stem and cerebellum.
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Key Findings & Data:MATERIAL and METHODS: 24 Wistar Albino adult male rats were randomly divided into four groups: group I consisted of control rats, and groups II-IV comprised electromagnetically irradiated (EMR) with 900, 1800 and 2450 MHz.
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Conclusion & Impact:This deterioration can cause to disease including loss of these areas function and cancer development.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: The aim of this study is to determine the structural changes of electromagnetic waves in the frontal cortex, brain stem and cerebellum. MATERIAL and METHODS: 24 Wistar Albino adult male rats were randomly divided into four groups: group I consisted of control rats, and groups II-IV comprised electromagnetically irradiated (EMR) with 900, 1800 and 2450 MHz. The heads of the rats were exposed to 900, 1800 and 2450 MHz microwaves irradiation for 1h per day for 2 months. results: While the histopathological changes in the frontal cortex and brain stem were normal in the control group, there were severe degenerative changes, shrunken cytoplasm and extensively dark pyknotic nuclei in the EMR groups. Biochemical analysis demonstrated that the Total Antioxidative Capacity level was significantly decreased in the EMR groups and also Total Oxidative Capacity and Oxidative Stress Index levels were significantly increased in the frontal cortex, brain stem and cerebellum. IL-1β level was significantly increased in the EMR groups in the brain stem. CONCLUSION: EMR causes to structural changes in the frontal cortex, brain stem and cerebellum and impair the oxidative stress and inflammatory cytokine system. This deterioration can cause to disease including loss of these areas function and cancer development.

Özet

AMAÇ: Bu çalışmanın amacı, frontal korteks, beyin sapı ve serebellumda elektromanyetik dalgaların yapısal değişikliklerini araştırmaktır. YÖNTEM ve GEREÇLER: 24 Wistar Albino sıçan rastgele 4 gruba bölündü: grup 1 kontrol grubu ve grup 2-4 900, 1800 ve 2450 MHz elektromanyetik radyasyona maruz kaldı. Sıçanların kafaları 900, 1800 ve 2450 MHz mikrodalgalara 2 ay boyunca her gün 1 saat maruz bırakıldı. BULGULAR: Kontrol grubunda histopatolojik değişiklikler, beyin sapında ve frontal kortekste normal bulunurken elektromanyetik radyasyon uygulanan gruplarda ciddi dejeneratif değişiklikler, küçülmüş sitoplazma ve geniş koyu piknotik nükleus mevcuttu. Biyokimyasal analizde total antioksidatif kapasite seviyesi elektromanyetik grupta anlamlı olarak azalmış bulunurken, total oksidatif kapasite ve oksidatif stres indeksi seviyeleri frontal korteks, beyin sapı ve serebellumda anlamlı olarak artmış bulundu. Elektromanyetik grupta beyin sapında IL-1β seviyesi anlamlı olarak artmıştı. SONUÇ: Elektromanyetik radyasyon beyin sapında, serebellumda ve frontal kortekste yapısal değişikliklere neden olmakta ve oksidatif stres ve inflamatuvar sitokin sistemini bozmaktadır. Bu bozulma kanser oluşumuna ve bu bölgelerin fonksiyon kaybını içeren hastalıklara neden olabilir.

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Cite This Article

ESER, O., SONGÜR, A., AKTAŞ, C., KARAVELİOĞLU, E., ÇAĞLAR, V., AYLAK, F., ÖZGÜNER, F., KANTER, M. (2013). Elektromanyetik dalgaların Sıçan Beyin dokusu Üzerine Etkileri: deneysel Çalışma. Turkish Neurosurgery, Cilt: 23 - Sayı: 6, 707–715. https://ajindex.com/articles/417849

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