Journals / Turkish Neurosurgery / 2013 / Cilt: 23 - Sayı: 1

Akciğer malignitelerinde inatçı ağrılar için Bt - rehberliğinde perkütan kordotomi

Ct-guided percutaneous cordotomy for intractable pain in what is more than a disease: Lung malignancies

Pages
81–87
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We suggest that cordotomy should be preferred as soon as possible in patients who fail to respond to the classic analgesic therapy.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: Lung cancer is the leading cause of cancer-related mortality worldwide.
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Key Findings & Data:MaterIal and Methods: Between 1987 and 2012, 224 patients with intractable pain were treated with computerized tomography (CT)- guided cordotomy.
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Conclusion & Impact:We suggest that cordotomy should be preferred as soon as possible in patients who fail to respond to the classic analgesic therapy.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

AIM: Lung cancer is the leading cause of cancer-related mortality worldwide. Pain is a common problem in these patients, yet inadequate or dissatisfactory management is prevalent. MaterIal and Methods: Between 1987 and 2012, 224 patients with intractable pain were treated with computerized tomography (CT)- guided cordotomy. Among them, 210 had intractable pain due to malignancies. The majority of the cases were diagnosed as pulmonary malignancies (108 patients). Sixty-seven were pulmonary carcinoma, 26 mesothelioma and 15 Pancoast tumors. Results: After cordotomy, 98.13% of cancer patients reported initial pain relief. Minimum and maximum preoperative scores of the Karnofsky Performance Scale were 20 and 70, versus postoperative scores of 40 and 90 (p<0.001). The median preoperative VAS score was 8 (6-9). On the first postoperative day, the score dropped sharply to 0 (0-8) (p<0.001). In this selected series of 108 percutaneous cordotomy procedures, as well as in the total series of 224 patients, there was no mortality or major morbidity. ConclusIon: CT-guided percutaneous cordotomy is an effective procedure that should be used in the treatment of cancer-related pain problems. We suggest that cordotomy should be preferred as soon as possible in patients who fail to respond to the classic analgesic therapy.

Özet

AMAÇ: Akciğer kanseri dünyada kansere bağlı ölüm nedenlerinin başında gelmektedir. Ağrı, bu hastalarda yaygın bir problem olmasına rağmen yetersiz veya tatmin etmeyen ağrı yönetimi yaygındır. YÖNTEM ve GEREÇLER: 1987-2012 yılları arasında, inatçı ağrısı olan 224 hasta bilgisayarlı tomografi (BT) rehberliğinde perkütan kordotomi yöntemiyle tedavi edildi. Bunların arasında, 210’unun inatçı ağrısı maligniteye bağlı idi. Vakaların büyük çoğunluğu pulmoner malignite (108 hasta), 67’si pulmoner karsinoma, 26’sı mezotelyoma ve 15’i Pancoast tümörü tanısı almışlardı. BULGULAR: Kordotomi uygulaması sonrasında kanser hastalarının % 98,13’ü ağrılarının başlangıçta geçtiğini bildirdiler. Karnofsky Performans Skalası skorlarının preoperatif minimum ve maksimum değerleri 20-70 iken, postoperatif değerler 40-90 idi (p<0,001). Preoperatif VAS skoru ortanca değeri 8 (6-9) idi. Postoperatif ilk günde bu skor bariz olarak 0 (0-8)’a düşmüştür (p<0,001). Toplam 224’lük seride olduğu gibi, seçilen 108 hastanın olduğu perkütan kordotomi serisinde de mortalite veya major morbidite yoktur. SONUÇ: BT rehberliğinde perkütan kordotomi etkili bir yöntem olup kansere bağlı inatçı ağrıların tedavisinde kullanılması gereklidir. Önerimiz, kordotominin, klasik analjezik terapilere yanıt vermeyen hastalarda zaman kaybedilmeden tercih edilmesi ve kullanılması yönündedir.

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Cite This Article

KANPOLAT, Y., ÖZDEMİR, M., Al-BEYATI, E. S. M. (2013). Akciğer malignitelerinde inatçı ağrılar için Bt - rehberliğinde perkütan kordotomi. Turkish Neurosurgery, Cilt: 23 - Sayı: 1, 81–87. https://ajindex.com/articles/417743

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References (1)

  1. American Cancer Society: Cancer Facts and Figures 2010. Atlanta: American Cancer Society, 2010 2. Bishay A, Raoof S, Esan A, Sung A, Wali S, Lee LY, George L, Saleh A, Baumann M: Update on pleural diseases--2007. Ann Thorac Med 2: 128-42, 2007 3. Brennan F, Cousins M: International Association for the Study of Pain. Pain relief as a human right. Pain Clin Updates 12(5): 1-4, 2004 4. Carr D, Goudas L, Lawrence D, Pirl W, Lau J, DeVine D, Kupelnick B, Miller K: Management of Cancer Symptoms: Pain, Depression, and Fatigue. Rockville, MD: Agency for Healthcare Research and Quality. Evidence Report/ Technology Assessment 61: 2-32, 2002 5. Cheng KK, Lee DT: Effects of pain, fatigue, insomnia, and mood disturbance on functional status and quality of life of elderly patients with cancer. Crit Rev Oncol Hematol 78: 127-137, 2011 6. Cleeland CS, Gonin R, Hatfield AK, Edmonson JH, Blum RH, Stewart JA, Pandya KJ: Pain and its treatment in outpatients with metastatic cancer. N Engl J Med 330: 592-596, 1994 7. Cleeland CS: Undertreatment of cancer pain in elderly patients. JAMA 279: 1914-1915, 1998 8. Cooley ME: Symptoms in adults with lung cancer: A systematic research review. J Pain Symptom Manage 19: 137-153, 2000 9. Eriksen J, Sjøgren P, Bruera E, Ekholm O, Rasmussen NK: Critical issues on opioids in chronic non-cancer pain. An epidemiological study. Pain 125: 172-179, 2006 10. Fallowfield L, Radcliffe D, Jenkins V, Saul J: Psychiatric morbidity and its recognition by doctors in patients with cancer. Br J Cancer 84: 1011-1015, 2001 11. Ferrell BR, Grant M, Ritchey KJ, Ropchan R, Rivera LM: The pain resource nurse training program: A unique approach to pain management. J Pain Symptom Manage 8: 549-556, 1993 12. Gordon DB, Dahl JL, Miaskowski C, McCarberg B, Todd KH, Paice JA, Lipman AG, Bookbinder M, Sanders SH, Turk DC, Carr DB: American Pain Society recommendations for improving the quality of acute and cancer pain management: American Pain Society Quality of Care Task Force. Arch Intern Med 165: 1574-1580, 2005 13. Gybels JM: Indications for the use of neurosurgical techniques in pain control. In: Bond MR, Charlton JE, Wolf J (eds), Proceedings of the Sixth World Congress on Pain. Amsterdam: Elsevier, 1995: 475 14. Hyndman OR, Van Epps C: Possibility of differential section of the spinothalamic tract; a clinical and histologic study. Arch Surg 38: 1036-1053, 1939 15. Jemal A, Bray F, Melissa M, Jacques F, Elizabeth W, David F: Global cancer statistics. CA Cance