Journals / Online Türk Sağlık Bilimleri Dergisi / 2022 / Cilt: 7 - Sayı: 1

Diagnostic and Prognostic Value of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratios on Acute Pancreatitis Patients

Akut Pankreatit Hastalarında Nötrofil/Lenfosit ve Trombosit/Lenfosit Oranlarının Tanısal ve Prognostik Değeri

Pages
80–85
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We found NLR as a parameter that can be used, applied, and accessed easily.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, we aim at demonstrating whether we can use neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratios (PLR) as a parameter in monitoring the disease severity of Pancreatitis Patients.
📊
Key Findings & Data:Materials and Methods: A total of 200 patients diagnosed with acute pancreatitis, hospitalized and monitored in gastroenterology service, whose files had retrospectively been studied, were included in the study.
💡
Conclusion & Impact:We found NLR as a parameter that can be used, applied, and accessed easily.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Akut pankreatit · Nötrofil/Lenfosit Oranı · Platelet/Lenfosit Oranı

Abstract

Objective: In this study, we aim at demonstrating whether we can use neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratios (PLR) as a parameter in monitoring the disease severity of Pancreatitis Patients. Materials and Methods: A total of 200 patients diagnosed with acute pancreatitis, hospitalized and monitored in gastroenterology service, whose files had retrospectively been studied, were included in the study. The severity and prognosis of acute pancreatitis were evaluated with the Atlanta classification. Results: The average of NLR was 9.84±9.60 in the patient group but 2.00±0.86 in the control group. The NLR level was found higher in the patient group. The cut-off value was found as 2.85 (Sensitivity: 86% and specificity: 81%). Although no significant change was found in terms of the average of NLR concerning the disease severity, the decrease in the average of NLR among the groups was found significant in 48 hours. Conclusion: We have found that only the change in NLR level in the first 48th-hour could be associated with the disease severity. We found NLR as a parameter that can be used, applied, and accessed easily.

Özet

Amaç: Bu çalışmada, pankreatit hastalarının hastalık şiddetinin izlenmesinde nötrofil-lenfosit oranı (NLO) ve trombosit-lenfosit oranlarının (TLO) bir parametre olarak kullanılıp kullanılamayacağını göstermeyi amaçladık. Materyal ve Metot: Akut pankreatit tanısı ile gastroenteroloji servisinde yatan ve takip edilen, dosyaları retrospektif olarak incelenen toplam 200 hasta çalışmaya dahil edildi. Akut pankreatitin şiddeti ve prognozu Atlanta sınıflaması ile değerlendirildi.Bulgular: NLO ortalaması hasta grubunda 9,84±9,60, kontrol grubunda ise 2,00±0,86 idi. Hasta grubunda NLO düzeyi yüksek saptandı ve cut-off değeri 2,85 olarak bulundu (Duyarlılık: %86 ve özgüllük: %81). Hastalık şiddetine göre NLO ortalamasında anlamlı bir değişiklik bulunmamakla birlikte, gruplar arasında NLO ortalamasındaki düşüş 48 saatte anlamlı bulundu. Sonuç: Sadece ilk 48 saatteki NLO düzeyindeki değişikliğin hastalık şiddeti ile ilişkili olabileceğini bulduk. NLO'nun kullanılabilecek, uygulanabilecek ve kolay ulaşılabilecek bir parametre olduğunu gördük.

🔖

Cite This Article

ERGENÇ, H., ERGENE, Z., EMİNLER, A. T., CİNEMRE, H. (2022). Diagnostic and Prognostic Value of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratios on Acute Pancreatitis Patients. Online Türk Sağlık Bilimleri Dergisi, Cilt: 7 - Sayı: 1, 80–85. https://ajindex.com/articles/417555

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (4)

  1. Akdur G, Bardakci O, Akdur O, Beyazit Y. Diagnostic utility of hematological indices in predicting adverse outcomes and severity of acute pancreatitis based on BISAP and modified Glasgow score. Turkish Journal of Trauma and Emergency Surgery. 2021. doi:10.14744/tjtes.2020.26348 Elbeyli A, Kurtul BE, Ozcan SC, Ozarslan Ozcan D. The diagnostic value of systemic immune-inflammation index in diabetic macular oedema. Clinical and Experimental Optometry. 2021. doi:10.1080/08164622.2021.1994337 Fang L, Yan F-H, Liu C, et al. Systemic inflammatory biomarkers, especially fibrinogen to albumin ratio, predict prognosis in patients with pancreatic cancer. Cancer Research And Treatment: Official Journal of Korean Cancer Association. 2021;53(1):131-139. doi:10.4143/crt.2020.330 Alagappan M, Pollom EL, von Eyben R, et al. Albumin and neutrophil-lymphocyte ratio (NLR) predict survival in patients with pancreatic adenocarcinoma treated with SBRT. American Journal Of Clinical Oncology. 2018;41(3):242-247.
  2. Djordjevic D, Rondovic G, Surbatovic M, et al. Neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume-to-platelet count ratio as biomarkers in critically ill and injured patients: which ratio to choose to predict outcome and nature of bacteremia? Mediators Of Inflammation. 2018. doi:10.1155/2018/3758068. Gao Y, Wang WJ, Zhi Q, et al. Neutrophil/lymphocyte ratio is a more sensitive systemic inflammatory response biomarker than platelet/lymphocyte ratio in the prognosis evaluation of unresectable pancreatic cancer. Oncotarget. 2017;8(51):88835-88844. doi:10.18632/oncotarget.21340 Garg PK, Singh VP. Organ failure due to systemic injury in acute pancreatitis. Gastroenterology. 2019;156(7):2008-2023.
  3. Zhang C, Liu H, Wang H, et al. The Predictive Value of Potential Hematological Biomarkers in Acute Coronary Syndrome. Clinical Laboratory. 2019;65(10). doi:10.7754/clin.lab.2019.181232 Hira¹ S, Tamam C. Diagnostic value of hematological parameters in patients with osteoarthritis. Cukurova Medical Journal. 2017;42(1):120-125.
  4. Yang Y, Yan S, Tian H, Bao Y. Macrophage inhibitory cytokine-1 versus carbohydrate antigen 19–9 as a biomarker for diagnosis of pancreatic cancer: A PRISMA-compliant meta-analysis of diagnostic accuracy studies. Medicine. 2018;97(9). doi:10.1097/MD.0000000000009994 James TW, Crockett SD. Management of acute pancreatitis in the first 72 hours. Current Opinion In Gastroenterology. 2018;34(5):330-335. d