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Journals / İstanbul Journal of Pharmacy / 2019 / Cilt: 49 - Sayı: 2

Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant

Serpil UGRAŞ
Sultan ÜLGER
Pınar GÖÇ RASGELE
Pages
45–52
Publication Date
2019-08-01
DOI
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Istanbul J Pharm 49 (2): 45-52.

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Objective & Hypothesis:DOI: 10.26650/IstanbulJPharm.2019.18001The aim of this study is to evaluate the antimicrobial, antioxidant, and antigenotoxic activity of extracts obtained from Diplotaenia cachrydifolia Boiss, which is traditionally used for food and medical treatment by the local people of Hakkâri Province (Turkey).
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Key Findings & Data:The DPPH IC50 values of the extracts were 2.5234 µg/mL, 6.0075 µg/mL, and 29.1974 µg/mL for ethanol, acetone, and hexane, respectively.
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Conclusion & Impact:Istanbul J Pharm 49 (2): 45-52.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Biological activity · genotoxicity · Diplotaenia cachrydifolia

Abstract

DOI: 10.26650/IstanbulJPharm.2019.18001The aim of this study is to evaluate the antimicrobial, antioxidant, and antigenotoxic activity of extracts obtained from Diplotaenia cachrydifolia Boiss, which is traditionally used for food and medical treatment by the local people of Hakkâri Province (Turkey). As a result of this study, the extracts of D. cachrydifolia exhibited a broad antimicrobial spectrum and high antimicrobial activity. It was also observed that the extracts had a high antioxidant activity. The DPPH IC50 values of the extracts were 2.5234 µg/mL, 6.0075 µg/mL, and 29.1974 µg/mL for ethanol, acetone, and hexane, respectively. The highest phenol content was found to be 55.36±0.035 μg/mL for ethanol. Furthermore, the ethanol extract was found to have a protective effect against mitomycin C-induced genotoxicity. D. cachrydifolia has a high biological activity; therefore, it is anticipated that future pharmacological studies will shed more light on this plant. Cite this article as: Uğraş S, Ülger S, Göç Rasgele P (2019). Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant. Istanbul J Pharm 49 (2): 45-52.

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Cite This Article

UGRAŞ, S., ÜLGER, S., RASGELE, P. G. (2019). Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant. İstanbul Journal of Pharmacy, Cilt: 49 - Sayı: 2, 45–52. https://ajindex.com/articles/41751

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