Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2018 / Cilt: 52 - Sayı: 4

Enflamatuvar deri hastalıklarında gebelik sonuçları

Pregnancy outcomes in inflammatory skin diseases

Pages
126–130
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

EDH’nin çoğu gebelik döneminde ya stabil seyretti ya da düzeldi.

📌 3 Key Takeaways

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Objective & Hypothesis:Amaç: Enflamasyon advers gebelik sonuçlarına yol açabilir.
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Key Findings & Data:Çalışmamızın amaçları çeşitli enflamatuvar deri hastalıklarının (EDH) gebelik sonuçlarına etkisini ve EDH’nin gebelikteki seyrini değerlendirmektir.
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Conclusion & Impact:EDH’nin çoğu gebelik döneminde ya stabil seyretti ya da düzeldi.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Amaç: Enflamasyon advers gebelik sonuçlarına yol açabilir. Romatoid artrit, enflamatuvar barsak hastalığı, sistemik lupus eritematozus ve psoriazis gibi enflamatuvar hastalıklar preterm doğum ve düşük doğum ağırlığı ile ilişkilendirilmektedir. Çalışmamızın amaçları çeşitli enflamatuvar deri hastalıklarının (EDH) gebelik sonuçlarına etkisini ve EDH’nin gebelikteki seyrini değerlendirmektir. Gereç ve Yöntem: Bu çok merkezli kohort çalışmasında, EDH hikayesi olan 32 gebe, sistemik hastalık tanılı 70 gebe ve 140 sağlıklı gebe şeklinde üç gruba ayrılmış toplam 242 gebe prospektif olarak analiz edildi. Bulgular: Advers gebelik sonucu oranı EDH grubunda %34,4, sistemik hastalıklar grubunda %37,1 ve sağlıklı gebe grubunda %25 olarak tespit edildi (p=0,16). Gestasyonel diabetes mellitus (%12,5) ve gebelik dönemi tiroid disfonksiyonu (%9,4) EDH grubunda en sık görülen advers gebelik sonuçlarıydı. EDH’nin gebelik boyunca seyri hastaların %50’sinde stabil iken, %28,1’inde iyileşme, %21,9’unda ise kötüleşme kaydedildi. Sonuç: EDH ve advers gebelik sonuçları arasında anlamlı bir ilişki gösterilemedi. EDH’nin çoğu gebelik döneminde ya stabil seyretti ya da düzeldi.

Özet

Background and Design: Inflammation can lead to adverse outcomes in pregnancy. Some inflammatory diseases, such as rheumatoidarthritis, inflammatory bowel disease, systemic lupus erythematosus, and psoriasis, are associated with preterm birth and low birth weight.The objectives of our study were to assess the effect of various inflammatory skin diseases (ISDs) on pregnancy outcomes and to evaluate thecourse of ISDs during pregnancy.Materials and Methods: In this multicenter cohort study, a total of 242 pregnant women in three groups including 32 pregnants with ahistory of ISDs, 70 pregnants with a diagnosis of systemic disease and 140 healthy pregnants were prospectively analyzed.Results: The rate of adverse pregnancy outcome was 34.4% in ISDs, 37.1% in systemic diseases and 25% in healthy pregnant groups (p=0.16).Gestational diabetes mellitus (12.5%) and thyroid dysfunction in pregnancy (9.4%) were the most common adverse outcomes of pregnancyseen in ISDs group. The disease course of ISDs was stable in 50%, improved in 28.1% and exacerbated in 21.9% of patients during pregnancy.Conclusion: We could not demonstrate a significant association between ISDs and adverse pregnancy outcomes. Most of the ISDs were eitherstable or improved during pregnancy.

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Cite This Article

ONAN, D. T., YORULMAZ, A., DİKMEN, A. U., YAKUTA, K., GÜLER, İ., ATALAY, C. R., ARTÜZ, R. F., YALÇIN, B. (2018). Enflamatuvar deri hastalıklarında gebelik sonuçları. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 52 - Sayı: 4, 126–130. https://ajindex.com/articles/417144

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