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Journals / Türk Hematoloji Onkoloji Dergisi / 2003 / Cilt: 13 - Sayı: 4

Posterior epidural aralıkta granulositik sarkom: Akut myeloid lösemide relapsın ilk belirtisi

Granulocytic sarcoma of the posterior epidural area: The presenting sign of relapse in acute myeloid leukemia

Zeynep A. YEGİN
Münci YAĞCI
Gülsan SUCAK
Pages
218–221
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We report a case of acute myeloid leukemia (AML)-M2 subtype with t(8,21) who appeared with acute paraplegia and a soft tissue mass in the epidural area between T9-T12 vertebras, while the patient was in complete remission ten months after the initial diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Granulocytic sarcoma is a rare extramedullary tumor of myeloid origin.
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Key Findings & Data:Acute myeloid leukemia with the translocation of the chromosomes between 8 and 21 is one of the situations in which granulocytic sarco-mas are reported to be more common.
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Conclusion & Impact:We report a case of acute myeloid leukemia (AML)-M2 subtype with t(8,21) who appeared with acute paraplegia and a soft tissue mass in the epidural area between T9-T12 vertebras, while the patient was in complete remission ten months after the initial diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erkek · Orta yaşlı · Sarkom

Abstract

Granulocytic sarcoma is a rare extramedullary tumor of myeloid origin. Acute myeloid leukemia with the translocation of the chromosomes between 8 and 21 is one of the situations in which granulocytic sarco-mas are reported to be more common. We report a case of acute myeloid leukemia (AML)-M2 subtype with t(8,21) who appeared with acute paraplegia and a soft tissue mass in the epidural area between T9-T12 vertebras, while the patient was in complete remission ten months after the initial diagnosis.

Özet

Granulositik sarkom myeloid kökenli ekstramedüller nadir bir tümördür. Akut myeloid lösemide t(8,21) bulunduran olgular ile sıklıkla birliktelik gösterir. Bu olgu sunumunda t(8,21) bulunduran ve ilk tanıdan on ay sonra remisyonda izlenirken T9-T12 epidural aralığındaki yumuşak doku kitlesinin akut paraplejiye neden olduğu bir AML-M2 vakası sunulmuştur.

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Cite This Article

YEGİN, Z. A., YAĞCI, M., SUCAK, G. (2003). Posterior epidural aralıkta granulositik sarkom: Akut myeloid lösemide relapsın ilk belirtisi. Türk Hematoloji Onkoloji Dergisi, Cilt: 13 - Sayı: 4, 218–221. https://ajindex.com/articles/417082

References (8)

  1. Menasce LP, Banerjee SS. et. al. Extramedullary Myeloid Tumour is often misdiagnosed: a study of 26 cases. Histopathology 34: 391-398, 1999
  2. Binder C, Tiemann M. et. al. Isolated meningeal chloroma (granulocytic sarcoma)- a case report and review of the literature. Ann Hematol 79: 459-462, 2000
  3. Aizawa T, Kokobun S, Hatori M. et. al. Extradural Granulocytic Sarcoma of the thoracic spine in Acute Myelogenous Leukemia with 8;21 chromosomme translocation. Tohoku J. Exp Med 178: 431-436, 1996
  4. Ang P, Virapongse C. Magnetic Resonance Imaging of spinal intradural Granulocytic Sarco- ma. Magn Reson Imaging 1990; 8: 95-100
  5. Deme S, Deadhare S S, Tucker WS. et. al. Gran- ulocytic Sarcoma of the spine in non-leukemic patients: Report of three cases. Neurosurgery 40: 1283-1287,1997
  6. Imrie KR, Kovacs MJ, Selby D. et. al. Isolated Chloroma: The effect of early antileukemic ther- apy. Ann Int Med 123: 351-353, 1996
  7. Wodzinski MA, Collin R, Winfield DA. et. al. Epidural Granulocytic Sarcoma in AML with t(8,21). Cancer 62: 1299-1300, 1988
  8. Mostavafi H, Lennarson PJ, Traynelis VC. Granulocytic Sarcoma of the spine. Neuro- surgery 46: 78-84, 2000.