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Journals / Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi (Online) / 2021 / Cilt: 4 - Sayı: 3

Adjuvants Used In Animal Vaccines-Their Formulations and Modes of Action: An Overview

Bilal AHMAD BHAT
Sheikh AADIL
Pages
492–506
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition, we will also learn about the challenges and opportunities in the development of animal vaccine adjuvants.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Vaccination has proven to be the most effective method for the prevention and control of infectious diseases in the animals and birds.
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Key Findings & Data:The success of vaccination depends on many factors but one of the important factor is the selection of most suitable and efficient adjuvant.
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Conclusion & Impact:In addition, we will also learn about the challenges and opportunities in the development of animal vaccine adjuvants.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Vaccination has proven to be the most effective method for the prevention and control of infectious diseases in the animals and birds. The success of vaccination depends on many factors but one of the important factor is the selection of most suitable and efficient adjuvant. An adjuvant is an ingredient of the vaccine which is used to improve the immune response in the animal’s body to vaccines. The inclusion of adjuvant to the vaccine preparation results in the abrupt stimulation of the immune system, production of the stronger immune response, activation of the specific type of immunity and increasing the half life of vaccine antigen. Previously, the role of adjuvants were poorly understood but with the increasing knowledge of the mechanism of action of adjuvants and the immune system, new adjuvants are being formulated that are safe and most effective against existing and emerging animal diseases. In this review, we will discuss about the current available adjuvants for animal vaccines with focus on their mechanism of action. In addition, we will also learn about the challenges and opportunities in the development of animal vaccine adjuvants.

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Cite This Article

BHAT, B. A., AADIL, S. (2021). Adjuvants Used In Animal Vaccines-Their Formulations and Modes of Action: An Overview. Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi (Online), Cilt: 4 - Sayı: 3, 492–506. https://ajindex.com/articles/414296

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References (13)

  1. Allen TM., Cullis PR. Liposomal drug delivery systems: From concept to clinical applications. Advanced Drug Delivery Reviews 2013; 65: 36-48.
  2. Bento D., Staats HF., Gonçalves T., Borges O. Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity. European Journal of Pharmaceutics and Biopharmaceutics 2015; 93: 149-164.
  3. Bozzuto G., Molinari A. Liposomes as nanomedical devices. International Journal of Nanomedicine 2015; 10: 975-999.
  4. Brownlie R., Allan B. Avian toll-like receptors. Cell and Tissue Research 2011; 343: 121-130.
  5. Brunner R., Jensen-Jarolim E., Pali-Schöll I. The ABC of clinical and experimental adjuvants-a brief overview. Immunology Letters 2010; 128: 29-35.
  6. Coffman RL., Sher A., Seder RA. Vaccine adjuvants: putting innate immunity to work. Immunity 2010; 33: 492-503.
  7. Cokcaliskan C., Turkoglu T., Sareyyupoglu B., Uzunlu E., Babak A., Özbilge BB., Gülyaz V. QS-21 enhances the early antibody response to oil adjuvant foot and-mouth disease vaccine in cattle. Clinical and Experimental Vaccine Research 2016; 5(2):138-147.
  8. Cordeiro AS., Alonso MJ., de la Fuente M. Nanoengineering of vaccines using natural polysaccharides. Biotechnology Advances 2015; 33: 1279-1293.
  9. Cunha IALD., Zulpo DL., Bogado ALG., Barros LDD.,Taroda A., Igarashi M., Navarro IT. Humoral and cellular immune responses in pigs immunized intranasally with crude rhoptry proteins of Toxoplasma gondii plus Quil-A. Veterinary Parasitology 2012; 186(3-4): 216-221.
  10. Dandashli EA., Zhao Q., Yitta S., Morefield GL., White JL. Hem SL. Effect of thermal treatment during the preparation of aluminum hydroxide adjuvant on the protein adsorption capacity during aging. Pharmacuetical Development and Technology 2002; 7(4): 401-406.
  11. Dar A., Lai K., Dent D., Potter A., Gerdts V., Babiuk LA., Mutwiri GK. Administration of poly (di(sodium carboxylatoethylphenoxy))phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs. Veterinary Immunology and Immunopathology 2012; 146(3-4): 289-295. Dell’Era L., Corona F., Daleno C., Scala A., Principi N., Esposito S. Immunogenicity, safety and tolerability of MF59-adjuvanted seasonal influenza vaccine in children with juvenile idiopathic arthritis. Vaccine 2012; 30: 936-940.
  12. Dowling JK, Dellacasagrande J. Toll-like receptors: ligands, cell-based models and readouts for receptor action. Methods in Molecular Biology 2016; 1390: 3-27.
  13. Freund J., Casals J., Hosmer EP. Sensitiz