Journals / Türkiye Acil Tıp Dergisi / 2013 / Cilt: 13 - Sayı: 2

Investigation of mad honey poisoning in patients with bradycardia detected

Bradikardi tespit edilen hastalarda deli bal zehirlenmesinin sorgulanması

Pages
93–95
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this our article we presented to the emergency department with complaints of weakness, nausea, vomiting and presyncope and electrocardiographic findings in patients with bradycardia wanted to emphasize to keep in mind in mad honey poisoning.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:North-facing slopes of the mountains, especially the Black Sea Region in Turkey, showing the natural distribution, popularly known as “mad honey” Grayanotoxine, has toxic effects on Na channels, the Ericaceae family of honey in the flower nectar and pollen is a natural product.
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Key Findings & Data:Our Emergency Department during the month of Octo ber of 2010, sweating, weakness, nausea, vomiting, and bradycardia,electrocardiographic findings in patients presenting with symptoms of presyncope identified as Mad honey poisoning was found in 5 cases.
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Conclusion & Impact:In this our article we presented to the emergency department with complaints of weakness, nausea, vomiting and presyncope and electrocardiographic findings in patients with bradycardia wanted to emphasize to keep in mind in mad honey poisoning.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

North-facing slopes of the mountains, especially the Black Sea Region in Turkey, showing the natural distribution, popularly known as “mad honey” Grayanotoxine, has toxic effects on Na channels, the Ericaceae family of honey in the flower nectar and pollen is a natural product. Mad honey poisoning cases often appeal with syncope, bradycardia, sweating, weakness, nausea, vomiting like symptoms. In more serious cases, AV block and cardiac rhythm disorders serious enough to be asistoliye. Our Emergency Department during the month of Octo ber of 2010, sweating, weakness, nausea, vomiting, and bradycardia,electrocardiographic findings in patients presenting with symptoms of presyncope identified as Mad honey poisoning was found in 5 cases. In this our article we presented to the emergency department with complaints of weakness, nausea, vomiting and presyncope and electrocardiographic findings in patients with bradycardia wanted to emphasize to keep in mind in mad honey poisoning.

Özet

Türkiye’de özellikle Karadeniz Bölgesindeki dağların kuzeye bakan yamaçlarında doğal yayılış gösteren, halk arasında daha çok “Deli bal” olarak bilinen grayanotoksin, Na kanalları üzerinde toksik etki gösteren, Ericaceae familyası bitkilerinin çiçek nektarı ve polenlerinden üretilen ballarda bulunan doğal bir üründür. Deli bal zehirlenmesinde olgular çoğunlukla senkop, bradikardi, terleme, halsizlik, bulantı ve kusma semptomları ile başvurmaktadır. Daha ciddi olgularda AV blok ve asistoliye kadar ciddi kardiyak ritm bozuklukları olabilir. Acil servisimize 2010 yılı Ekim ayı boyunca, terleme, halsizlik, bulantı, kusma ve presenkop şikayetleri ile başvuran hastalar içinde EKG bulgusu bradikardi olarak tespit edilen 5 olgunun deli bal zehirlenmesine bağlı olduğu saptanmıştır. Bu yazıda halsizlik, bulantı, kusma ve presenkop şikayetleri ile acil servise başvuran ve EKG bulgusu bradikardi olan hastalarda ‘’Deli bal zehirlenmesi’’nin de akılda tutulmasını vurgulamak istedik.

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Cite This Article

ATİK, D., ŞELİMAN, B. (2013). Investigation of mad honey poisoning in patients with bradycardia detected. Türkiye Acil Tıp Dergisi, Cilt: 13 - Sayı: 2, 93–95. https://ajindex.com/articles/413978

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References (15)

  1. Leach DG. Ancient curse of the Rhododendron. Am Horticul- turist. 1972;51:20-29
  2. Stevens PF. Rhododendron L. In: Davis PF, editor. Flora of Tur- key and the East Aegean Islands. Edinburgh: Edinburgh Uni- versity Press; 1978. p. 90-4
  3. Gunduz A, Turedi S, Uzun H, Topbas M. Mad honey poisoning. Am J Emerg Med 2006;24:595-8
  4. Onat FY, Yegen BC, Lawrence R, Oktay A, Oktay S. Mad honey poisoning in man and rat. Rev Environ Health 1991;9:3-9
  5. Brown BS, Akera T, Brody TM. Mechanism of grayanotoxin III- induced afterpotentials in feline cardiac Purkinje fibers. Eur J Pharmacol 1981;75:271-81
  6. Yilmaz O, Eser M, Sahiner A, Altintop L, Yesildag O. Hypoten- sion, bradycardia and syncope caused by honey poisoning. Resuscitation 2006;68:405-8
  7. Seyama I, Yamaoka K, Yakehiro M, Yoshioka Y, Morihara K. Is the site of action of grayanotoxin the sodium channel gating of squid axon? Jpn J Physiol 1985;35:401-10
  8. Sütlüpinar N, Mat A, Satganoğlu Y. Poisoning by toxic honey in Turkey. Arch Toxicol 1993;67:148-50
  9. Biberoğlu S, Biberoğlu K, Komsuoğlu B. Mad honey. JAMA 1988;259:1943
  10. Aşçıoğlu M, Özesmi Ç, Doğan P, Özturk F. Effects of acute Grayanotoxin-I administration on hepatic and renal functions in rats. Turk J Med Sci 2000;30:23-7
  11. Cetin NG, Marcıl E, Kıldıran M, Ogüt S. Hepatotoxicity with mad honey Turk J Emerg Med 2009;9:84-6
  12. Ozhan H, Akdemir R, Yazici M, Gündüz H, Duran S, Uyan C. Cardiac emergencies caused by honey ingestion: a single centre experience. Emerg Med J 2004;21:742-4
  13. Gunduz A, Durmus I, Turedi S, Nuhoglu I, Ozturk S. Mad honey poisoning-related asystole. Emerg Med J 2007;24:592-3
  14. Gunduz A, Turedi S, Russell RM, Ayaz FA. Clinical review of grayanotoxin/mad honey poisoning past and present. Clin Toxicol (Phila) 2008;46:437-42
  15. Choi YS, Jang IS. A case of severe bradyarrhythmia after in- gestionof Rhododendron bradycarpum. Korean Circulation J 2002;32:268-7014.